Ближайшие клинические и структурные результаты артроскопической реконструкции верхней капсулы у пациентов с артропатией плечевого сустава на фоне массивного разрыва вращательной манжеты

The purpose of the study was to evaluate the nearest clinical, functional and structural (according to MRI) results of arthroscopic reconstruction of the shoulder upper capsule using an acellular dermal collagen matrix and auto-tissue of the ileotibial band in the patients with shoulder arthropathy after a massive rotator cuff tear. Material and Methods. The study included 30 patients with stage I–IV shoulder arthropathy according to K. Hamada classification. All of them were undergone the arthroscopic reconstruction of the upper part of the shoulder capsule in 2017–2018. The orthopedic procedures were performed by the same surgical team using an acellular dermal collagen matrix as a biological material (group 1) and auto-tissue of the iliotibial band (group 2). Results. The proportion of the patients with good — 8 (26.7%), satisfactory — 14 (46.6%) and poor — 8 (26.7%) surgical outcomes was determined according to the ASES functional assessment scales. Transplant ruptures were recorded in one (3.3%) patient in the group with an acellular dermal collagen matrix and in two (6.6%) patients in the group with the iliotibial autograft. Conclusion. Arthroscopic reconstruction of the upper part of the shoulder capsule is a promising method for the surgical treatment of physically active working age patients with shoulder arthropathy after massive rotator cuff tear. The main goals are restoration of the shoulder vertical stability, centered position of the humeral head towards the glenoid, and improvement of the shoulder biomechanics as a whole.Цель исследования — оценить ближайшие клинико-функциональные и структурные (по данным МРТ) результаты артроскопической реконструкции верхней капсулы плечевого сустава с использованием бесклеточного дермального коллагенового матрикса и аутоткани подвздошно-большеберцового тракта у пациентов с артропатией плечевого сустава на фоне массивного разрыва вращательной манжеты. Материал и методы. В исследование были включены 30 пациентов с артропатией плечевого сустава I–IV стадии по классификации K. Hamada на фоне массивного разрыва вращательной манжеты плечевого сустава, которым в период 2017–2018 гг. одной хирургической бригадой была выполнена артроскопическая реконструкция верхней капсулы плечевого сустава с использованием в качестве биологического материала бесклеточного дермального коллагенового матрикса (группа 1) и аутоткани подвздошно-большеберцового тракта (группа 2). Результаты. В соответствии с показателями по шкале функциональной оценки ASES были определены следующие результаты проведенных вмешательств: хорошие — 8 (26,7%), удовлетворительные — 14 (46,6%) и плохие — 8 (26,7%). Разрывы трансплантата были зарегистрированы у одного (3,3%) пациента в группе с бесклеточным дермальным коллагеновым матриксом и у двоих (6,6%) с аутотрансплантатом подвздошно-большеберцового тракта. Заключение. Артроскопическая реконструкция верхней капсулы плечевого сустава является перспективным методом хирургического лечения физически активных пациентов трудоспособного возраста с артропатией плечевого сустава на фоне массивных разрывов вращательной манжеты плечевого сустава, а основной задачей является восстановление вертикальной стабильности плечевого сустава, центрированного положения головки плечевой кости по отношению к суставной впадине лопатки и улучшение биомеханики плеча в целом

Photo and electroluminescence behavior of Tb(ACAC)3phen complex used as emissive layer on organic light emitting diodes

This work shows the luminescence properties of a rare-earth organic complex, the Tb(ACAC)3phen. The results show the 5D4 -> 7F3,4,5,6 transitions with no influence of any ligand emission. The photoluminescence excitation spectrum is tentatively interpreted by the ligands absorption. An OLED was made by thermal evaporation (total thickness of 1200 Å) using TPD and Alq3 as hole and electron transport layers, respectively. The light emission reproduces the photoluminescence spectrum of the terbium complex at room temperature, with CIE (x,y) color coordinates of (0.28, 0.55). No presence of any bands from the ligands was observed. The potential use of this compound in efficient devices is discussed

Influence of crustal fracturing on the thermal springs and earthquake swarms distribution in the north-east part of the Baikal rift system (Russia)

The Baikal rift system faults, having developed in the recent rift formation period, are characterized by hydrothermal and seismic activity. Especially in the northeastern part, the level of fracturing affects the localization of thermal outlets and the distribution of earthquake swarms. The specific features of the hydrothermal outputs and seismicity interposition, depending on the fracture heterogeneity and water saturation of the lithosphere layers, have not been previously evaluated. The results of the statistical analysis of the hydrothermal data, presented herein, show that most of the springs are distributed in areas of increased fault density. Multiple less hot hydrotherms are associated with zones of maximum density in the inter-block space. The spatio-temporal analysis of seismicity showed that migrations of weak and moderate seismic activity propagate from earthquake swarms through these zones. Swarms initiate the deformation front by propagating in the quasiplastic layer of the upper mantle at a speed of tens of kilometers per year, which can increase the aqueous fluid pore pressure in the lower earth’s crust, facilitate the movement of the fluid upwards along the section, and cause a process of successive stress relaxation in zones of high fracturing and concentration of hydrothermal springs. Earthquake swarms occur in areas of about average fracture density, associated with deep faults framing consolidated blocks of the earth’s crust. The hydrotherms with high or average temperature, and with probable deep source chemical composition components are related with such zones

Thermal and Magnetic Field Sensors Based on Injection-coupled Devices

Operation principle and possible applications of a novel type of silicon integrated circuit (IC) device – injection-coupled device (ICD) – are addressed. Examples of possible ICD electrical and physical designs are examined in detail. These are based on the existing CMOS and use bipolar technologies. It is shown that in active mode only one cell of ICD-based sensor chain consumes power. This circumstance enables one to achieve an extraordinarily low power consumption compared to the CMOS ICs. This is because the power consumption of an ICD as a whole is not different of that of a single cell in its IC matrix. These advantages make ICDs highly attractive for a number of important applications, such as, e.g., radiation detectors or magnetic and thermal field detectors. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3625

Effect of crystalline and amorphic phenol on characteristics of peptidases and glycosidases in chironomid larvae

The effects of crystalline and amorphous phenol (0.5 mmol/L) on the characteristics of glycosidases, as well as casein-lytic and hemoglobin-lytic peptidases, which function in the whole body of chironomid larvae Chironomus sp. were studied. Crystalline phenol decreased the activity of glycosidases in comparison to the control in the temperature range 0–50 ºС, amorphous phenol – in the temperature range 0–70 ºС. The temperature optimum of glycosidases in whole body of chironomid larvae in control and experiment corresponds to 50 ºС. The activity of glycosidases in comparison to the control decreased in the pH range 5–11 (to a greater extent in the case of the lower fraction). Amorphous phenol increased the activity of casein-lytic peptidases in comparison to the control in the temperature range of 30–50 ºС, hemoglobin-lytic peptidases – in the temperature range of 0–60 ºС. The degree of the increase of enzyme activity in the temperature optimum zone of casein-lytic and hemoglobin-lytic peptidases was different: the level of enzyme activity in the experiment was higher than in the control by 2.3 and 1.8 times, respectively. The temperature optimum of the studied peptidases of chironomid larvae, regardless of the experimental conditions, corresponds to 40 °C. Crystalline phenol did not actually affect the Q10 values of glycosidases in the temperature range 0–50 °C. Amorphous phenol decreased the Q10 values at a temperature of 40–50 °C. The Q10 values of casein-lytic peptidases increased in most cases, the Q10 values of hemoglobin-lytic peptidases decreased in the presence of amorphous phenol. The process of protein hydrolysis was characterized by a break in the Arrhenius plot at 20 °C. The values of Еact in the range 0–20 °С were lower than in the zone of higher temperatures. The Еact values of the process of casein hydrolysis by peptidases of all tissues of chironomid larvae in the presence of amorphous phenol in both temperature zones increased. The Еact values of the process of hemoglobin hydrolysis by peptidases of all tissues of chironomid larvae in the presence of amorphous phenol in both temperature zones decreased. The Еact values of the process of starch hydrolysis in the presence of crystalline phenol decreased. The amorphous phenol changed the Еact values in different directions. They slightly increased in the presence of the phenol upper fraction, but they decreased in the presence of the phenol lower fraction. The data obtained indicate a significant effect of crystalline and amorphous phenol not only on activity, but also on the characteristics of peptidases and glycosidases that function in the whole body of chironomid larvae

Analysis of the p-i-n-structures Electrophysical Characteristics Influence on the Spectral Characteristics Sensitivity

In this paper the simulation of the silicon p-i-n-photodiodes spectral sensitivity characteristics was carried out. The analysis of the semiconductor material characteristics (the doping level, lifetime, surface recombination velocity), the construction and operation modes on the photosensitive structures characteristics in order to optimize them were investigated

NMR as Used in the Russian and Foreign Pharmacopoeias for Quality Control of Medicinal Products

The ongoing development of the Pharmacopoeia of the Eurasian Economic Union and the current trend for harmonisation of the Russian Pharmacopoeia with the world leading pharmacopoeias suggest the necessity of studying how different pharmacopoeias use nuclear magnetic resonance (NMR) for quality control of medicinal products. The aim of the study was to compare the extent of medicine quality characteristics assessed by NMR in the Russian and foreign pharmacopoeias. The review summarises the experience of various national and world pharmacopoeias in using the NMR method for quality control of medicines and certification of pharmacopoeial reference materials. The comparative analysis covered the following quality parameters: active ingredient identification, determination of the composition of non-stoichiometric compounds, determination of the average polymer chain length in polymers and block copolymers, determination of the absolute content of the active ingredient, identification and quantification of impurities, polymorphism, and crystallinity. It was shown that the United States and Japanese Pharmacopoeias are leading the way in introducing the NMR method into pharmacopoeial analysis. There have been some positive trends in the introduction of the NMR method in the State Pharmacopoeia of the Russian Federation as well. It was concluded that changes are needed in the general chapters “Nuclear Magnetic Resonance Spectroscopy” and “Reference Standards” of the State Pharmacopoeia of the Russian Federation, 14th ed. in order to harmonise the texts with those of the Eurasian Pharmacopoeia and the European Pharmacopoeia and to allow for the possibility of direct identification of a substance by complex analysis of NMR spectral data, without comparing the test sample and the reference standard spectra. The NMR method should be included in the list of absolute methods used for determination of purity of primary chemical reference substances during certification

АРТРОСКОПИЧЕСКИЙ ШОВ БОЛЬШИХ И МАССИВНЫХ РАЗРЫВОВ ВРАЩАТЕЛЬНОЙ МАНЖЕТЫ ПЛЕЧЕВОГО СУСТАВА: КЛИНИЧЕСКИЕ РЕЗУЛЬТАТЫ И ДАННЫЕ МРТ

Purpose of the study – to identify incidence rate of recurrent rotator cuff (RC) tears, to evaluate outcomes of arthroscopic bone-tendon anchor suture, to determine the factors influencing arthroscopic treatment outcomes.Materials and methods. Medical history data, pre-operative x-rays and MRI of shoulder joints of 305 patients (main group) who underwent arthroscopic bone-tendon anchor suture repair of large or massive RC tears during 2010-2016 were included in the study. Follow up period ranged from 1 to 6 years postoperatively with mean value of 25,6±4,5 months. Telephone survey of patients was conducted after the surgery as well as a single examination of patients with evaluation by functional scales – UCLA, ASES, CS, VAS, DN4. Preoperative standard x-rays in AP and axial views were done in all patients. Arthropathy severity was evaluated by K.Hamada classification. Comparison of patient specific data, features of RC lesions and surgical treatment was made by Kruskal-Wallis test.Results. Good outcomes by ASES, CS and UCLA functional scales were obtained in 15 (5%) of patients, satisfactory – in 213 (69.8%), poor – in 77 (25.2%). Postoperative MRI data provided the following sub-distribution of patients: 49 (41.1%) patients with complete repair of RC tendons lesions, 38 (31.9%) patients with partial repair and 33 (27.0%) patients with recurrent tear of reconstructed tendon. Correlation analysis allowed to establish the limits for achieving good outcomes of arthroscopic bone-tendon anchor suturing for significant association with infraspinatus muscle atrophy (not exceeding 40%) and fatty infiltration of supraspinatus muscle (not exceeding 23.5%). В настоящее время отсутствует единый подход к хирургическому лечению пациентов с большими и массивными разрывами ВМПС. Поэтому выбор рациональной лечебной тактики остается открытым.Цель исследования – выявить частоту повторных разрывов ВМПС, оценить результаты артроскопического костно-сухожильного якорного шва, определить факторы, влияющие на исходы артроскопического лечения.Материал и методы. Материалом исследования послужили данные историй болезни, дооперационные рентгенограммы и МРТ плечевых суставов 305 пациентов (основная группа), которым был выполнен артроскопический костно-сухожильный якорный шов большого или массивного разрыва ВМПС в период с 2010 по 2016 г. Сроки наблюдения составили от 1 года до 6 лет после выполненных операций, средний срок – 25,6±4,5 мес. После хирургического вмешательства были проведены опрос пациентов по телефону и однократный осмотр с заполнением функциональных шкал UCLA, ASES, CS, ВАШ, ДН-4. Всем больным проводили дооперационную стандартную рентгенографию плечевого сустава в прямой и аксиальной проекциях. Степень выраженности артропатии плечевого сустава оценивали по классификации K. Hamada. Сравнение данных, характеризующих пациентов, особенности повреждения вращательной манжеты и проводимого хирургического лечения проводили с помощью теста Краскела — Уоллиса.Результаты. По шкалам функциональной оценки ASES, CS и UCLA хорошие результаты были получены у 15 (5%) пациентов, удовлетворительные — у 213 (69,8%), плохие — у 77 (25,2%). В соответствии с результатами послеоперационных МРТ-исследований были выделены следующие подгруппы пациентов: с полным восстановлением поврежденных сухожилий вращательной манжеты — 49 (41,1%), частичным восстановлением – 38 (31,9%) и с повторным разрывом реконструированной сухожильной ткани – 33 (27,0%). Корреляционный анализ позволил установить границы достижения хороших результатов артроскопического костно-сухожильного якорного шва для значимых связей с такими показателями, как мышечная атрофия подостной мышцы (не более 40%) и жировая инфильтрация надостной мышцы (не более 23,5%).

The Spectral Sensitivity Characteristics Simulation of the Silicon p-i-n-structure with High Resistance

In the paper a simulation program for photovoltaic parameters of semiconductor devices and results of their investigation are presented. The results of the program usage based on an example of calculating the influence of the high-resistance "well" thickness in the silicon p-i-n-diode spectral response are discussed. For the accuracy of the program estimation it was compared the theoretical spectral characteristics of a silicon PIN-diode 5 kOhm substrate with the experimental data