426 research outputs found
Cyclosporine treatment of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report and brief review of the literature
Systemic corticosteroids are often considered the treatment of choice in the management of severe drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, in instances when systemic steroids are contraindicated, when there is an inadequate response to steroids, or when a prolonged course of steroids is not ideal, alternate therapies may be considered. Cyclosporine has been reported as a successful alternative immunosuppressive therapy; however, only a few cases have been reported in the literature. This observational case report presents an instance where cyclosporine was successfully used to treat DRESS syndrome in a patient where systemic steroids were ineffective
Electronic and magnetic structure of epitaxial NiO/FeO(001) heterostructures grown on MgO(001) and Nb-doped SrTiO(001)
We study the underlying chemical, electronic and magnetic properties of a
number of magnetite based thin films. The main focus is placed onto
NiO/FeO(001) bilayers grown on MgO(001) and Nb-SrTiO(001)
substrates. We compare the results with those obtained on pure FeO(001)
thin films. It is found that the magnetite layers are oxidized and Fe
dominates at the surfaces due to maghemite (-FeO) formation,
which decreases with increasing magnetite layer thickness. From a layer
thickness of around 20 nm on the cationic distribution is close to that of
stoichiometric FeO. At the interface between NiO and FeO we
find the Ni to be in a divalent valence state, with unambiguous spectral
features in the Ni 2p core level x-ray photoelectron spectra typical for NiO.
The formation of a significant NiFeO interlayer can be excluded by
means of XMCD. Magneto optical Kerr effect measurements reveal significant
higher coercive fields compared to magnetite thin films grown on MgO(001), and
a 45 rotated magnetic easy axis. We discuss the spin magnetic moments
of the magnetite layers and find that the moment increases with increasing thin
film thickness. At low thickness the NiO/FeO films grown on
Nb-SrTiO exhibits a significantly decreased spin magnetic moments. A
thickness of 20 nm or above leads to spin magnetic moments close to that of
bulk magnetite
Axial light emission and Ar metastable densities in a parallel plate dc micro discharge in steady state and transient regimes
Axial emission profiles in a parallel plate dc micro discharge (feedgas:
argon; discharge gap d=1mm; pressure p=10Torr) were studied by means of time
resolved imaging with a fast ICCD camera. Additionally, volt-ampere (V-A)
characteristics were recorded and Ar* metastable densities were measured by
tunable diode laser absorption spectroscopy (TDLAS). Axial emission profiles in
the steady state regime are similar to corresponding profiles in standard size
discharges (d=1cm, p=1Torr). For some discharge conditions relaxation
oscillations are present when the micro discharge switches periodically between
low current Townsend-like mode and normal glow. At the same time the axial
emission profile shows transient behavior, starting with peak distribution at
the anode, which gradually moves towards the cathode during the normal glow.
The development of argon metastable densities highly correlates with the
oscillating discharge current. Gas temperatures in the low current
Townsend-like mode (T= 320-400K) and the high current glow mode (T=469-526K)
were determined by the broadening of the recorded spectral profiles as a
function of the discharge current.Comment: submitted to Plasma Sources Sci. Techno
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