Postural stability of the young athletes of coordination sports with signs of undifferentiated connective tissue dysplasia

Objective: researching of stabilometric parameters of primary school children, doing complex coordination types of sport and having the features of undifferentiated connective tissue dysplasia (UCTD). Materials and methods: 36 children at the age from 7 to 11 years engaged in gymnastics and sports aerobics were examined. All athletes were divided into two groups, taking into account the presence or absence of UCTD signs based on results of a screening algorithm «Outward signs score of systemic involvement of connective tissue in children». Postural function assessment was carried out by the standard method (intermediate foot position) on the «Force plate ST-150». Results: athletes with UCTD were worse than their healthy peers across the majority of stabilometric indicators (

МНОГОФАКТОРНЫЙ АНАЛИЗ ТЕХНОЛОГИЧЕСКИХ ПРОЦЕССОВ МЕХАНООБРАБОТКИ С ИСПОЛЬЗОВАНИЕМ МЕТОДОВ КОМПЬЮТЕРНОГО МОДЕЛИРОВАНИЯ

The paper contains a method of technical and economical analysis of technological processes according to such criteria as cost price, power consumption, consumption of human labour or amount of the material to be removed. Machining the part «Rukav» of 12211221-2407018Б/-01 and 1522-2407018/-01 agricultural machinery models as an example it is shown how due to utilization of new hard alloy coating of a cutting tool it is possible to reach significant economic effect.Представлена методика технико-экономического анализа технологических процессов по критериям себестоимости, энергопотребления, трудозатрат или объема снимаемого металла, и на примере технологического процесса механической обработки детали «Рукав» моделей 1221-2407018Б/-01 и 1522-2407018/-01 сельскохозяйственной техники показано, как за счет использования нового твердосплавного покрытия режущего инструмента достичь значительного экономического эффекта

Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [¹⁸F]FDG: version 1.0

Positron emission tomography (PET) has been widely used in paediatric oncology. 2-Deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is the most commonly used radiopharmaceutical for PET imaging. For oncological brain imaging, different amino acid PET radiopharmaceuticals have been introduced in the last years. The purpose of this document is to provide imaging specialists and clinicians guidelines for indication, acquisition, and interpretation of [18F]FDG and radiolabelled amino acid PET in paediatric patients affected by brain gliomas. There is no high level of evidence for all recommendations suggested in this paper. These recommendations represent instead the consensus opinion of experienced leaders in the field. Further studies are needed to reach evidence-based recommendations for the applications of [18F]FDG and radiolabelled amino acid PET in paediatric neuro-oncology. These recommendations are not intended to be a substitute for national and international legal or regulatory provisions and should be considered in the context of good practice in nuclear medicine. The present guidelines/standards were developed collaboratively by the EANM and SNMMI with the European Society for Paediatric Oncology (SIOPE) Brain Tumour Group and the Response Assessment in Paediatric Neuro-Oncology (RAPNO) working group. They summarize also the views of the Neuroimaging and Oncology and Theranostics Committees of the EANM and reflect recommendations for which the EANM and other societies cannot be held responsible

MULTI-FACTOR ANALYSIS OF TECHNOLOGICAL MECHANICAL MACHINING PROCESSES WHILE USING METHODS OF COMPUTER MODELING

The paper contains a method of technical and economical analysis of technological processes according to such criteria as cost price, power consumption, consumption of human labour or amount of the material to be removed. Machining the part «Rukav» of 12211221-2407018Б/-01 and 1522-2407018/-01 agricultural machinery models as an example it is shown how due to utilization of new hard alloy coating of a cutting tool it is possible to reach significant economic effect

Lean body mass correction of standardized uptake value in simultaneous whole-body positron emission tomography and magnetic resonance imaging

This study explores the possibility of using simultaneous positron emission tomography—magnetic resonance imaging (PET-MRI) to estimate the lean body mass (LBM) in order to obtain a standardized uptake value (SUV) which is less dependent on the patients' adiposity. This approach is compared to (1) the commonly-used method based on a predictive equation for LBM, and (2) to using an LBM derived from PET-CT data. It is hypothesized that an MRI-based correction of SUV provides a robust method due to the high soft-tissue contrast of MRI. A straightforward approach to calculate an MRI-derived LBM is presented. It is based on the fat and water images computed from the two-point Dixon MRI primarily used for attenuation correction in PET-MRI. From these images, a water fraction was obtained for each voxel. Averaging over the whole body yielded the weight-normalized LBM. Performance of the new approach in terms of reducing variations of 18F-Fludeoxyglucose SUVs in brain and liver across 19 subjects was compared with results using predictive methods and PET-CT data to estimate the LBM. The MRI-based method reduced the coefficient of variation of SUVs in the brain by 41  ± 10% which is comparable to the reduction by the PET-CT method (35  ± 10%). The reduction of the predictive LBM method was 29  ± 8%. In the liver, the reduction was less clear, presumably due to other sources of variation. In conclusion, employing the Dixon data in simultaneous PET-MRI for calculation of lean body mass provides a brain SUV which is less dependent on patient adiposity. The reduced dependency is comparable to that obtained by CT and predictive equations. Therefore, it is more comparable across patients. The technique does not impose an overhead in measurement time and is straightforward to implement

Whole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation

Aim!#!In 2015, the revised International Pediatric Non-Hodgkin Lymphoma Staging System was published. It mentions [!##!Materials and methods!#!Ten pediatric patients with histologically proven non-Hodgkin lymphoma underwent whole-body [!##!Results!#!Of the 190 lymph node regions evaluated, four were rated controversial. Consensus was reached by considering metabolic, functional and morphologic information combined. Concordantly, [!##!Conclusion!#!Despite the small number of cases evaluated, whole-body

Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0

Positron emission tomography (PET) has been widely used in paediatric oncology. 2-Deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is the most commonly used radiopharmaceutical for PET imaging. For oncological brain imaging, different amino acid PET radiopharmaceuticals have been introduced in the last years. The purpose of this document is to provide imaging specialists and clinicians guidelines for indication, acquisition, and interpretation of [18F]FDG and radiolabelled amino acid PET in paediatric patients affected by brain gliomas. There is no high level of evidence for all recommendations suggested in this paper. These recommendations represent instead the consensus opinion of experienced leaders in the field. Further studies are needed to reach evidence-based recommendations for the applications of [18F]FDG and radiolabelled amino acid PET in paediatric neuro-oncology. These recommendations are not intended to be a substitute for national and international legal or regulatory provisions and should be considered in the context of good practice in nuclear medicine. The present guidelines/standards were developed collaboratively by the EANM and SNMMI with the European Society for Paediatric Oncology (SIOPE) Brain Tumour Group and the Response Assessment in Paediatric Neuro-Oncology (RAPNO) working group. They summarize also the views of the Neuroimaging and Oncology and Theranostics Committees of the EANM and reflect recommendations for which the EANM and other societies cannot be held responsible.Keywords: DOPA; FDG; FET; Gliomas; MET; PET-CT; Paediatric PET; Paediatric brain imaging; Paediatric oncology

Comparison of Interim PET Response to Second-Line Versus First-Line Treatment in Classic Hodgkin Lymphoma: Contribution to the Development of Response Criteria for Relapsed or Progressive Disease.

In first-line treatment of Hodgkin lymphoma (HL), Deauville scores 1-3 define complete metabolic remission. Interim <sup>18</sup> F-FDG PET is also used for relapse-treatment adaptation; however, PET response criteria are not validated for relapse treatment. Methods: We performed a pairwise comparative analysis of early response to first- and second-line treatments in 127 patients with classic HL who experienced relapse. The patients participated in the prospective, multicenter EuroNet-PHL-C1 study. Residual uptake was measured retrospectively using the qPET method, a validated semiautomatic quantitative extension of the Deauville score. Empiric cumulative distribution functions of the qPET values were used to systematically analyze the response to first- and second-line treatments. Results: Individual patients responded variably to first- and second-line treatments. However, the empiric cumulative distribution functions of the qPET values from all patients were nearly superimposable. Conclusion: The findings support that first- and second-line treatments in HL do not require different response criteria