Emotion expressivity in the Dutch:Validation of the Dutch translation of the Berkeley Expressivity Questionnaire

When examining emotions and emotion regulation, we discriminate between emotion experience and emotion expressivity. Research shows that the two are modestly related. The Berkeley Expressivity Questionnaire (BEQ) was designed to assess positive and negative expressivity, as well as the intensity of the expressive behavior. The current article reports on 2 studies that examined the reliability and validity of the Dutch translation of the BEQ. In Study 1, we performed a confirmatory factor analysis of the BEQ items in two samples that differed in age (young adults and adults), correlated the facet and total scores with measures of behavioral control, affective response tendencies, and emotion regulation strategies, and examined sex differences. Results confirmed the three-factor structure and further showed that factors were correlated, and two items loaded on all factors. Internal consistency was good, and test–retest reliability was excellent. As expected, emotion expression was larger in women. Convergent and divergent validity were confirmed. Behavioral control measures were inversely related to emotion expression. Although neuroticism and depression were associated with negative expressivity, extraversion, openness, and agreeableness were associated with positive expressivity. Emotion regulation strategies generally showed association patterns in the expected directions. In Study 2, we report on the predictive value of the BEQ facet scores for the emotional response to acute social evaluative stress. Results showed that only expression intensity was significantly associated with a larger emotional stress response. In conclusion, the Dutch version of Berkeley Expressivity Questionnaire is a reliable and valid instrument to be used in the Dutch settin

Self-care and pathophysiological function in patients with chronic heart failure

Background Self-care is assumed to benefit physiological function associated with prognosis in patients with chronic HF, but studies examining these relations are lacking. This study aims to prospectively examine the association of self-reported HF self-care with HF-associated pathophysiological markers, including renal, hematological, and immune function. Method Patients with chronic HF (n = 460, 66.2 ± 9.6 years, 75% men) completed questionnaires and provided blood samples at baseline and 12-month follow-up. Linear mixed models examined random intercept and fixed between- and within-subjects effects of global self-care and the individual self-care behaviors on log-transformed TNF-α, IL-6, and IL-10, the glomerular filtration rate of creatinine (GFRcreat), and hemoglobin (Hb), controlling for sociodemographic and clinical covariates. Results Self-care was independently associated with lower GFRcreat levels (β = − .14, P = .023) and improvement in self-care with a reduction in GFRcreat (β = − .03, P = .042). Individual self-care behaviors were differentially associated with renal, inflammatory, and hematological markers. Regular exercise was associated with level differences in IL-6 (P < .001), and improvement in exercise was associated with increasing GFRcreat (P = .002) and increasing Hb (P = .010). Fluid restriction was associated with lower overall GFRcreat (P = .006), and improvement in fluid restriction was associated with decreasing GFRcreat (P = .014). Low-sodium intake was associated with lower levels of Hb (P = .027), lower TNF-alpha (P = .011), and lower IL-10 (P = .029). Higher levels of medication adherence were associated with reduced pro-inflammatory activation (P < .007). Conclusion Our findings suggest that better global self-care was associated with poorer renal function. Performing self-care behaviors such as regular exercise and medication adherence was associated with improved physiological functioning, while restriction of fluid and sodium, and the associated daily weight monitoring were associated with adverse levels of pathophysiological biomarkers

A systematic review comparing two popular methods to assess a Type D personality effect

Introduction:  Type D personality, operationalized as high scores on negative affectivity (NA) and social inhibition (SI), has been associated with various medical and psychosocial outcomes. The recent failure to replicate several earlier findings could result from the various methods used to assess the Type D effect. Despite recommendations to analyze the continuous NA and SI scores, a popular approach groups people as having Type D personality or not. This method does not adequately detect a Type D effect as it is also sensitive to main effects of NA or SI only, suggesting the literature contains false positive Type D effects. Here, we systematically assess the extent of this problem. Method:  We conducted a systematic review including 44 published studies assessing a Type D effect with both a continuous and dichotomous operationalization. Results:  The dichotomous method showed poor agreement with the continuous Type D effect. Of the 89 significant dichotomous method effects, 37 (41.6%) were Type D effects according to the continuous method. The remaining 52 (58.4%) are therefore likely not Type D effects based on the continuous method, as 42 (47.2%) were main effects of NA or SI only. Conclusion:  Half of the published Type D effect according to the dichotomous method may be false positives, with only NA or SI driving the outcome

Optimized Energy Management of a Solar and Wind Equipped Student Residence with an Innovative Hybrid Energy Storage System

Grid-connected Energy Storage Systems (ESS) are vital for transforming the current energy sector. Lithium-Ion Battery (LIB) technology is presently the most popular form of ESS, especially because of its fast response capability, efficiency, and reducing market prices, but is not always preferred for long-term storage, due to its relatively shorter lifetime. A Redox Flow Battery (RFB) on the other hand has a higher lifetime and better long-term storage capability, but has a higher upfront cost and reduced round trip efficiency. A Hybrid ESS (HESS) consisting of LIB and RFB offers the advantages of both technologies, thus making the ESS more economical and flexible to use while also improving the cycle lifetime of individual ESS. Such a grid-connected HESS is planned and installed for a student residence at Bruchsal having 126 apartments for 150 students and equipped with 220 kWp photovoltaics and 10.5 kWp wind-power. Real-time high-resolution data of the residence’s electrical load and energy generation are collected and used to optimally control the HESS. Additionally, the RFB is also used as heat storage, which supports partial heating requirements of the residence. In the present work, an Energy Management System (EMS) is deployed which not only controls this conglomerate but also optimizes its operations in real-time. The HESS is optimized two folds where it is operated with a fixed priority based strategy to improve the operational efficiency. Secondly using solar and load predictions, optimal charging schedules of the individual ESS are estimated. Based on the schedules the ESS are charged at its optimal charging points thus increasing charging efficiency and at the same time it avoids the ESS from staying at high SOC ranges for long time thus reducing ageing. Results based on real life operations based on the proposed methods are provided in this work

Assessing the temporal stability of psychological constructs:An illustration of Type D personality, anxiety and depression

Various methods exist to assess the temporal stability of psychological constructs. In this paper we discuss common methods based on a review of the personality traits negative affectivity and social inhibition. Most methods ignore the non-normal distributions and measurement error in the questionnaire item scores. We illustrate how to handle these issues using three longitudinal latent variable models. We further highlight the importance of testing the often overlooked assumption of longitudinal measurement invariance. Lastly, we apply several longitudinal measurement invariance models, univariate and multivariate latent growth curves models, and latent trait-state occasions models to data from 2625 cancer survivors, to assess the temporal stability of negative affectivity, social inhibition, depression, anxiety, across a period of four years

Changes in perceived stress and lifestyle behaviors in response to the COVID-19 pandemic in The Netherlands:An online longitudinal survey study

The COVID-19 pandemic has substantial implications for physical and mental wellbeing. This study investigated changes, over time, in lifestyle behaviors and perceived stress during the initial phase of the pandemic and associations with COVID-19 symptoms, in the Dutch general population. An online longitudinal survey study was performed with pre-lockdown measurements in February, and subsequently in April and June 2020 (n = 259, mean age 59 ± 14 years, 59% women). Self-report questionnaires were used to assess weight, diet quality, physical activity, alcohol intake, and smoking. Perceived stress was measured using the validated perceived stress scale (PSS-10). The presence of COVID-19 symptoms (yes/no) was defined as fever, or >3 of the following symptoms: weakness/tiredness, muscle ache, dry cough, loss of smell/taste, and breathing difficulties. Data were analyzed using linear mixed models, adjusted for age, sex, educational level, marital status and (change in) employment status. Minimal increases over time were observed in alcohol intake (0.6 ± 0.7 to 0.7 ± 1.1 glasses/day, p = 0.001) and smoking (9.5 ± 8.7 to 10.9 ± 9.4 cigarettes/day among 10% smokers, p = 0.03), but other lifestyle behaviors remained stable. In April 2020, 15% reported COVID-19-related symptoms, and in June 2020, this was 10%. The presence of COVID-19 symptoms was associated with increased perceived stress (p interaction = 0.003) and increased alcohol consumption (p interaction = 0.03) over time. In conclusion, in this prospective study, COVID-19 symptoms were associated with increases in perceived stress and alcohol consumption. Future research on biopsychosocial determinants and underlying mechanisms of lifestyle changes, as a response to the COVID-19 pandemic, is needed

Multi-modal responses to the Virtual Reality Trier Social Stress Test: A comparison with standard interpersonal and control conditions

The Trier Social Stress Test (TSST) is a reliable social-evaluative stressor. To overcome limitations of the in vivo TSST, a standardized virtual reality TSST (VR-TSST) was developed. The present study compares the emotional (anxiety) and physiological (heart period and variability) response to a VR-TSST with an in vivo TSST and a control condition. Participants took part in either an in vivo TSST (N = 106, 64% female), VR-TSST (N = 52, 100% female), or a control TSST (N = 20, 40% female). Mixed linear modeling examined response profile differences related to TSST type. While there was an equivalent anxiety response to the in vivo TSST as the VR-TSST, we found a smaller heart period and heart rate variability response in VR-TSST compared to the in vivo TSST, especially in response to the math part of the test. The present findings demonstrate that social evaluative stress can be successfully induced in a VR setting, producing similar emotional and slightly attenuated cardiovascular responses

Dexverapamil to modulate vinblastine resistance in metastatic renal cell carcinoma

Multidrug resistance (MDR) in a variety of human tumours such as renal cell carcinoma (RCC) is thought to be caused by expression of the MDR1 gene and may be reversed by applying modern chemosensitisers such as dexverapamil, which inhibit the MDR1 gene product P-glycoprotein. This preliminary report gives information on a clinical study complying with good clinical practice regulations in patients with advanced RCC. The final evaluation is pending. Vinblastine, if anything the most effective chemotherapeutic agent (5-day continuous regimen), was combined with oral dexverapamil (6 times per day) as a chemosensitiser and dexamethasone to increase dexverapamil tolerance. All patients had histologically proven RCC, which was metastatic and progressive at study entry. The statistical design featured a pre-study regimen of two cycles of vinblastine alone followed by evaluation. If no response was documented, with all patients thus serving as their own control, dexverapamil and dexamethasone were added for three cycles of combination therapy. Having obtained institutional permission from the ethical review committee, we enrolled patients of whom 25 qualified for the combined-treatment arm; 13 patients finished the study, 5 patients failed to complete all treatment cycles (1 because of treatment-related toxicity, 3 for personal reasons, not related to treatment, 1 for tumour-related reasons) and 7 patients were at too early a stage for evaluation. Altogether, 61% of all patients tolerated a dose of dexverapamil of at least 2400 mg/day with peak serum levels reaching, in some cases, approximately 8 μM (the sum of dexverapamil plus nordexverapamil levels). WHO grade 3 and 4 toxicities were mainly myelosuppression (5/18). The combination of 1.4 mg m-2 day-1 vinblastine plus dexverapamil was generally felt to be safe and well tolerated. One partial response and 7 stable diseases were noted in this heavily pretreated study population. Four-hourly administration of dexverapamil in combination with dexamethasone plus escalation to the individually tolerated doses have permitted increases in serum levels of dexverapamil