Counter Chemotactic Flow in Quasi-One-Dimensional Path

Quasi-one-dimensional bidirectional particle flow including the effect of chemotaxis is investigated through a modification of the John-Schadschneider-Chowdhury-Nishinari model. Specifically, we permit multiple lanes to be shared by both directionally traveling particles. The relation between particle density and flux is studied for several evaporation rates of pheromone, and the following results are obtained: i) in the low-particle-density range, the flux is enlarged by pheromone if the pheromone evaporation rate is sufficiently low, ii) in the high particle-density range, the flux is largest at a reasonably high evaporation rate and, iii) if the evaporation rate is at the level intermediate between the above two cases, the flux is kept small in the entire range of particle densities. The mechanism of these behaviors is investigated by observing the spatial-temporal evolution of particles and the average cluster size in the system.Comment: 4 pages, 9 figure

Lattice Forward-Secure Identity Based Encryption Scheme

Abstract Protecting secret keys is crucial for cryptography. There are some relatively insecure devices (smart cards, mobile phones etc.) which have threat of key exposure. The goal of the forward security is to protect security of past uses of key even if the current secret key is exposed. In this paper we propose lattice based forward-secure identity based encryption scheme based on LWE assumption in random oracle model. We also propose lattice based forward-secure identity based encryption scheme in the standard model

Negative &#948;<SUP>13</SUP>C excursion and anoxia at the Permo-Triassic boundary in the Tethys Sea

The Permian-Triassic (P-T) sections in Spiti valley, Himalaya represent sedimentary deposits of a shallow sea and show a sharp negative transition of &#948; 13C in total organic matter, kerogen fraction and carbonate phase. This excursion occurs across the upper part of the Permian shale culminating in a ferruginous band, which marks the peak of anoxicity after a period of generally low-oxygenated condition in the basin, as inferred on the basis of trace element analysis. Presence of carbon isotopic shift along with anoxia is similar to that observed in many P-T sections over the globe and suggests that Permo-Triassic transitional records of the Neo-Tethys are preserved in the ferruginous band of the Spiti valley sections

From the cell membrane to the nucleus: unearthing transport mechanisms for Dynein

Mutations in the motor protein cytoplasmic dynein have been found to cause Charcot-Marie-Tooth disease, spinal muscular atrophy, and severe intellectual disabilities in humans. In mouse models, neurodegeneration is observed. We sought to develop a novel model which could incorporate the effects of mutations on distance travelled and velocity. A mechanical model for the dynein mediated transport of endosomes is derived from first principles and solved numerically. The effects of variations in model parameter values are analysed to find those that have a significant impact on velocity and distance travelled. The model successfully describes the processivity of dynein and matches qualitatively the velocity profiles observed in experiments

Electron-Spin Excitation Coupling in an Electron Doped Copper Oxide Superconductor

High-temperature (high-Tc) superconductivity in the copper oxides arises from electron or hole doping of their antiferromagnetic (AF) insulating parent compounds. The evolution of the AF phase with doping and its spatial coexistence with superconductivity are governed by the nature of charge and spin correlations and provide clues to the mechanism of high-Tc superconductivity. Here we use a combined neutron scattering and scanning tunneling spectroscopy (STS) to study the Tc evolution of electron-doped superconducting Pr0.88LaCe0.12CuO4-delta obtained through the oxygen annealing process. We find that spin excitations detected by neutron scattering have two distinct modes that evolve with Tc in a remarkably similar fashion to the electron tunneling modes in STS. These results demonstrate that antiferromagnetism and superconductivity compete locally and coexist spatially on nanometer length scales, and the dominant electron-boson coupling at low energies originates from the electron-spin excitations.Comment: 30 pages, 12 figures, supplementary information include

Ethnobotany in the Nepal Himalaya

<p>Abstract</p> <p>Background</p> <p>Indigenous knowledge has become recognized worldwide not only because of its intrinsic value but also because it has a potential instrumental value to science and conservation. In Nepal, the indigenous knowledge of useful and medicinal plants has roots in the remote past.</p> <p>Methods</p> <p>The present study reviews the indigenous knowledge and use of plant resources of the Nepal Himalayas along the altitudinal and longitudinal gradient. A total of 264 studies focusing on ethnobotany, ethnomedicine and diversity of medicinal and aromatic plants, carried out between 1979 and 2006 were consulted for the present analysis. In order to cross check and verify the data, seven districts of west Nepal were visited in four field campaigns.</p> <p>Results</p> <p>In contrast to an average of 21–28% ethnobotanically/ethnomedicinally important plants reported for Nepal, the present study found that up to about 55% of the flora of the study region had medicinal value. This indicates a vast amount of undocumented knowledge about important plant species that needs to be explored and documented. The richness of medicinal plants decreased with increasing altitude but the percentage of plants used as medicine steadily increased with increasing altitude. This was due to preferences given to herbal remedies in high altitude areas and a combination of having no alternative choices, poverty and trust in the effectiveness of folklore herbal remedies.</p> <p>Conclusion</p> <p>Indigenous knowledge systems are culturally valued and scientifically important. Strengthening the wise use and conservation of indigenous knowledge of useful plants may benefit and improve the living standard of poor people.</p

Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.

Gas1 and Boc/Cdon act as co-receptors in the vertebrate Hedgehog signalling pathway, but the nature of their interaction with the primary Ptch1/2 receptors remains unclear. Here we demonstrate, using primordial germ cell migration in mouse as a developmental model, that specific hetero-complexes of Ptch2/Gas1 and Ptch1/Boc mediate the process of Smo de-repression with different kinetics, through distinct modes of Hedgehog ligand reception. Moreover, Ptch2-mediated Hedgehog signalling induces the phosphorylation of Creb and Src proteins in parallel to Gli induction, identifying a previously unknown Ptch2-specific signal pathway. We propose that although Ptch1 and Ptch2 functionally overlap in the sequestration of Smo, the spatiotemporal expression of Boc and Gas1 may determine the outcome of Hedgehog signalling through compartmentalisation and modulation of Smo-downstream signalling. Our study identifies the existence of a divergent Hedgehog signal pathway mediated by Ptch2 and provides a mechanism for differential interpretation of Hedgehog signalling in the germ cell niche

Total, regional and unilateral body composition of professional English first-class cricket fast bowlers

There have been few reports of advanced body composition profiles of elite fast bowlers in the sport of cricket. Therefore, the aim of the current study was to determine total, regional and unilateral body composition characteristics of elite English first-class cricket fast bowlers in comparison with matched controls, using dual-energy X-ray absorptiometry (DXA). Twelve male fast bowlers and 12 age-matched, non-athletic controls received one total-body DXA scan. Anthropometric data were obtained as well as left and right regional (arms, legs and trunk) fat mass, lean mass and bone mineral content. Fast bowlers were significantly taller and heavier than controls (P<0.05). Relative to body mass, fast bowlers possessed greater lean mass in the trunk (80.9±3.7 vs. 76.7±5.9%; P=0.047) and bone mineral content in the trunk (2.9±0.3 vs. 2.6±0.3%; P=0.049) and legs (5.4±0.5 vs. 4.6±0.6%; P=0.003). In the arm region, fast bowlers demonstrated significantly greater unilateral differences in bone mineral content (10.6±6.6 vs. 4.5±3.9%; P=0.012). This study provides specific body composition values for elite-level fast bowlers and highlights the potential for muscle and bone imbalances that may be useful for conditioning professionals. Our findings also suggest beneficial adaptations in body composition and bone mass in fast bowlers compared with their non-athletic counterparts