A NOVEL STILL IMAGE MOSAIC ALGORITHM CONSTRUCTION USING FEATURE BASED METHOD

An image mosaic is a method of assembling multiple overlapping images of same scene into a larger one. The output of image mosaic will be the union of two input images. In this paper we have to use three step automatic image mosaic method. The first step is taking two input images and finding out the corners in both the images, second step is finding its matched corner and third step is its blending and we get final output mosaic. The experimental results show the proposed algorithm produces an improvement in mosaic accuracy, efficiency and robustness

Post COVID-19 lung fibrosis and pleural effusion in geriatric patient

An 81-year-old male who has hypertension in the last 15 years coming to our hospital with a chief complaint of severe breathlessness, chest pain with a history of fever spike in the last 20 days. When he underwent real-time reverse transcription-polymerase chain reaction (RT-PCR) test, the test comes positive with SARS COVID-19. Routine test high-resolution computed tomography (HRCT) showed approximately 75% of the left side and 50% of right lung involvement with CO-RAD 6 and HRCT severity score 20. HRCT showed multiple ill-defined patchy ground-glass opacity with consolidation and septal thickening in the bilateral lung field. There is a finding of fibrotic changes with tractional bronchiectasis in bilateral lung field with minimal pleural effusion

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CLOPIDOGREL BISULFATE IN HUMAN PLASMA BY RP-HPLC

Objective: A simple, sensitive, rapid and precise bioanalytical RP-HPLC method was developed for estimation of clopidogrel bisulfate in human plasma. Methods: The work was carried out on Shimadzu LC-2010 CHT HPLC system equipped with Waters C18 (250×4.6 mm, 5μ) column with a mobile phase containing acetonitrile: methanol: water (75:20:05 v/v/v). The flow rate of mobile phase was 1 ml/min and the detection was carried out at 225 nm. The retention time of clopidogrel bisulfate was found to be 4.6 min. Results: The developed bioanalytical method was found to be linear in the concentration range of 30.76-69.23 µg/ml. The simple regression analysis of chromatographic response showed the value of R2= 0.9917. The precision study revealed that the cumulative percentage variation was within acceptable limit and accuracy study showed the value of mean percent recovery between 103.60 to 109.80 %. The clopidogrel was stable in human plasma at different storage conditions. Conclusion: The validation parameters of the method met the acceptance criteria. Sufficient stability of both LQC and HQC was shown to allow for completion of sample analysis in clinical trials. From the results, we can conclude that developed bioanalytical method is simple, rapid, accurate, and precise and can be used for routine analysis of clopidogrel bisulfate. Keywords: Bioanalytical Method, Clopidogrel Bisulfate, RP-HPLC, Validatio

Study of clinical outcome of acromioclavicular joint injury type III-VI treated by EndoButton and threads in adults

Background: Acromioclavicular joint dislocations are common in physically active young adults that too most common in persons who are participating in sports activities. Incidence is more in males who are participating in contact sports like rugby, basketball, hockey. It accounts for 9% of all shoulder injuries. Literature says the incidence is 3-4/1,00,000 population. The aim of the present study was to study the functional outcome of acromioclavicular joint after reconstruction of both acromioclavicular and coracoclavicular ligament using endo button system and to provide pain-free, mobile shoulder.Methods: In the present study, 15 patients were selected of age group 20-60 years. Acromioclavicular joint injuries are classified according to Rockwood classification and the findings from the physical examination and anteroposterior and axillary radiographs. All patients were treated as per status of injury level by either conservatively or operatively with open reduction and reconstruction of both ligament by using endo button thread system and its outcomes were assessed clinically and radiologically.Results: Patients were evaluated using American shoulder and elbow score (ASES) score and Constant shoulder score. Average ASES score was 90 (range 68.3-98.3) and constant score was 88 (range 63-96). According to constant score 7 patients had excellent outcome, 6 patients had good outcome, 2 patients had adequate outcome. All patients reported satisfaction with the treatment. The patients were followed upto 6 months.Conclusions: The technique proved to be effective in treating acute. Acromioclavicular joint dislocations (Rockwood type III-VI) with a high degree of patient satisfaction

Characterization And Optimization Of Recombinant Gm-Csf Protein: Expression And Functional Analysis

Background: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) emerges as a key influencer, wielding its impact over haematopoiesis and immune modulation. It can address an array of intricate physiological and pathological scenarios. Objective: The present study is aimed to characterize and optimize the recombinant GM-CSF protein and to carry out its expression and functional analysis. Methods: GS115 (Pichia pastoris) strain was double digested with restriction enzymes 5’AOX1 and 3’AOX1α and ligated to the pPICZα vector. The positive clones were screened using PCR, mobility shift, Kex2 signal cleavage and restriction digestion. Further, the Pichia strain with pPICZα A was transformed into yeast cells, and its expression was studied using Spectroscopy and SDS-PAGE. In addition, the resulting Protein was purified using reverse-phase column chromatography and functional characterization was performed using a Pichia pastoris HCP kit. Results: The GM-CSF protein was successfully transformed into yeast cells, andtheSDS-PAGE profile confirmed the presence of GM-CSF in the expression system. A purified form of recombinant GM-CSF protein was obtained using HPLC, and the obtained chromatograms of both reference and test samples were comparable. Further, from the functional analysis, about9.67 ppm of the functional hematopoietic cell phosphatase (HCP) was observed in the purified GM-CSF sample. Conclusion: The Recombinant GM-CSF has been successfully prepared and confirmed for their expression and functional characteristics. The developed Protein can regulate production, cell differentiation and granulocytic functions

A NOVEL APPROACH FOR VERIFIABLE SECRET SHARING IN PROACTIVE NETWORK USING RSA

We consider perfect verifiable secret sharing (VSS) in a synchronous network of n processors (players) where a designated player called the dealer wishes to distribute a secret s among the players in a way that none of them obtain any information, but any t + 1 players obtain full information about the secret. The round complexity of a VSS protocol is defined as the number of rounds performed in the sharing phase. Gennaro, Ishai, Kushilevitz and Rabin showed that three rounds are necessary and sufficient when n > 3t. Sufficiency, however, was only demonstrated by means of an inefficient (i.e., exponential-time) protocol and the construction of inefficient three-round protocol were left as an open problem. In this paper, we present an efficient three-round protocol for VSS. The solution is based on a three-round solution of so-called weak verifiable secret sharing (WSS), for which we also prove that three rounds are a lower bound. Furthermore, we also demonstrate that one round is sufficient for WSS when n > 4t, and that VSS can be achieved in 1 + " amortized rounds (for any " > 0) when n > 3t

Cystic tuberculosis of the scapula in a young boy: a case report and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>Tuberculosis of the flat bones is rare and only a small percentage involves the scapular bone.</p> <p>Case presentation</p> <p>We report a rare case of tuberculosis of the scapula in a 14-year-old. Diagnostic clues include lytic areas with low density seen in the body of the scapula involving a glenoid margin associated with typical clinical features. Treatment should include a regimen of four antitubercular drugs along with surgical debridement if required.</p> <p>Conclusion</p> <p>Although rare, tuberculosis should be suspected in patients presenting with a chronic sinus in the scapular region, particularly in the developing world.</p

Active Flow Control over a NACA23012 Airfoil using Hybrid Jet

A time-dependent numerical simulation is performed to examine the flow separation control with the action of a hybrid jet (the combination of synthetic and continuous jets) over a NACA23012 airfoil. The unsteady Reynolds-averaged Navier–Stokes (URANS) simulation is performed with Spalart-Allmaras (SA) turbulence model to simulate the flow field around the airfoil to analyse the effect of the hybrid jet. A combined jet is placed at the point of flow separation on the upper surface of the airfoil which is located at the 12% of the chord length from the leading edge of the airfoil for a given flow configuration. Flow simulations are performed at a chord-based Reynolds number of 2.19 × 106 for the hybrid jet oscillating frequency of 0.159 at a blowing ratio of 3.0. The contribution of the continuous jet in the hybrid jet is evident by the flow control. Variation in the continuous jet velocity is studied, which improved the aerodynamic characteristics of the airfoil. The maximum improvement in lift to drag ratio is observed from 11.19 to 22.14 at an angle of attack of 22 degree. The stall angle also shows an enhancement from 18 degree to 20 degree

In Rain or Shine: Understanding and Overcoming Dataset Bias for Improving Robustness Against Weather Corruptions for Autonomous Vehicles

Several popular computer vision (CV) datasets, specifically employed for Object Detection (OD) in autonomous driving tasks exhibit biases due to a range of factors including weather and lighting conditions. These biases may impair a model's generalizability, rendering it ineffective for OD in novel and unseen datasets. Especially, in autonomous driving, it may prove extremely high risk and unsafe for the vehicle and its surroundings. This work focuses on understanding these datasets better by identifying such "good-weather" bias. Methods to mitigate such bias which allows the OD models to perform better and improve the robustness are also demonstrated. A simple yet effective OD framework for studying bias mitigation is proposed. Using this framework, the performance on popular datasets is analyzed and a significant difference in model performance is observed. Additionally, a knowledge transfer technique and a synthetic image corruption technique are proposed to mitigate the identified bias. Finally, using the DAWN dataset, the findings are validated on the OD task, demonstrating the effectiveness of our techniques in mitigating real-world "good-weather" bias. The experiments show that the proposed techniques outperform baseline methods by averaged fourfold improvement.Comment: Under revie

Towards an improved understanding of plasticity, friction and wear mechanisms in precipitate containing AZ91 Mg alloy

This work reports a combined experimental and atomistic simulation study on continuous precipitates (CPs) and discontinuous precipitates (DPs) affecting the scratch induced wear in AZ91 magnesium alloy. Nanoscratching experiments complemented by atomic simulations were performed to understand the directional dependence and origins of plasticity, friction and wear mechanisms as benchmarked to nanocrystalline HCP magnesium. Post scratch deformation analysis was performed using electron back scattering diffraction, scanning electron microscope and molecular dynamics (MD) simulation. The direction of orientation of the precipitates was observed to make a significant influence on the deformation behaviour. For example, regardless of the precipitates type (CP or DP), a ductile-brittle transition becomes pronounced while scratching along the direction (orientation) of precipitates, whilst a fully ductile response was obtained while scratching along the direction normal to the precipitates. However, regardless of the direction of orientation, DPs showed a higher wear resistance and coefficient of friction compared to the CPs. These observations were supported by the quantitative analysis of the planar defects such as coherent twins, extrinsic and intrinsic stacking faults in the deformation zone as well as 1/3〈11¯00〉" role="presentation"> ( and 1/3〈12¯10〉" role="presentation"> dislocations type extracted from the MD analysis.These observations will facilitate an improved design of AZ91 alloys in particular and intermetallic precipitate containing alloys in general