336 research outputs found

    DIFFERENTIAL EFFECT OF NATIONAL VS. REGIONAL CELEBRITIES ON CONSUMER ATTITUDES

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    The present study explores the differential effects of having a National/Regional celebrity in an advertisement/ endorsement. More specifically the study intends to find out whether a National celebrity would have a more favorable impact on consumer attitudes than a Regional celebrity when endorsing the same product. Experimental design was used as the research methodology. A 3 (National Celebrity/Regional Celebrity/No Celebrity) X 2 (High/Low Involvement Product) design was conducted on student sample. The experiment was conducted on a total of 240 respondents with fictitious ads as stimuli. National celebrities were found to create more favorable consumer attitudes than regional celebrities. However, the National celebrity was also found to create a more favorable consumer attitude given the product was low involvement. It was interesting to find that the no celebrity treatment created more favorable consumer attitudes than regional celebrity condition. The study suggested that celebrity endorsements were useful but the nature of the product also has an influence on the success. One limitation was the restriction to print advertisements and another was restriction to celebrity of only one region. A major implication for the manager is that it is always better to use a National celebrity than a regional one. However, for high involvement products, celebrity endorsement need not be the only success factor. The contribution of the study is in an area which is well researched but addressing a research question which has not been investigated before.Celebrity endorsement, Consumer Attitudes, Experimental Design, Regional celebrity.

    D4-Magic Graphs

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    Consider the set X = {1, 2, 3, 4} with 4 elements. A permutation of X is a function from X to itself that is both one one and on to. The permutations of X with the composition of functions as a binary operation is a nonabelian group, called the symmetric group S 4 . Now consider the collection of all permutations corresponding to the ways that two copies of a square with vertices 1, 2, 3 and 4 can be placed one covering the other with vertices on the top of vertices. This collection form a nonabelian subgroup of S 4 , called the dihedral group D 4 . In this paper, we introduce A-magic labelings of graphs, where A is a finite nonabelian group and investigate graphs that are D 4 -magic. This did not attract much attention in the literature

    Augmented Lagrangian Methods as Layered Control Architectures

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    For optimal control problems that involve planning and following a trajectory, two degree of freedom (2DOF) controllers are a ubiquitously used control architecture that decomposes the problem into a trajectory generation layer and a feedback control layer. However, despite the broad use and practical success of this layered control architecture, it remains a design choice that must be imposed a prioria\ priori on the control policy. To address this gap, this paper seeks to initiate a principled study of the design of layered control architectures, with an initial focus on the 2DOF controller. We show that applying the Alternating Direction Method of Multipliers (ADMM) algorithm to solve a strategically rewritten optimal control problem results in solutions that are naturally layered, and composed of a trajectory generation layer and a feedback control layer. Furthermore, these layers are coupled via Lagrange multipliers that ensure dynamic feasibility of the planned trajectory. We instantiate this framework in the context of deterministic and stochastic linear optimal control problems, and show how our approach automatically yields a feedforward/feedback-based control policy that exactly solves the original problem. We then show that the simplicity of the resulting controller structure suggests natural heuristic algorithms for approximately solving nonlinear optimal control problems. We empirically demonstrate improved performance of these layered nonlinear optimal controllers as compared to iLQR, and highlight their flexibility by incorporating both convex and nonconvex constraints

    Formulation and Evaluation of Itraconazole Nanocapsules

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    An objective of a present research has been able to prepare as well as analyze Itraconazole Nanocapsules through using emulsion solvent evaporation method. Itraconazole has been overfilled of ethyl cellulose & hydroxypropyl methylcellulose Nanocapsules and that was able to prepare through emulsion solvent evaporation technique. The outcomes like Fourier transform infrared implied a steady identity like Itraconazole Nanocapsules filled as for ethyl cellulose Nanocapsules and then also absence like drug - excipient interplay. Compatibility research findings like FTIR & differential scanning have been used to start investigating that there's no incompatability inside the composition. A morphometric size of the particles like Itraconazole Nanocapsules has been done through SEM. Nanocapsules has been analyzed such as total composition codes has been f1 to f8. A % yield has been obtained to be 73.22% to 88.91%. Drug content has been 65.9 to 98.4%. A size of the particles like Nanocapsules 80 µm to 22 µm, drug entrapment efficiency has been 54.3% to 91.3 %, a drug loading capabilities has been 97.8% to 56.9%. A swellability studies has been 0.6 sec to 1.6 sec. in vitro dissolution studies like best formulation f8 has been did find of being 61.78%. An In-vitro drug dissolution obtained data has been equipped to numerous mathematical equations such like zero order, 1st order, higuchi matrix & korsmeyer peppas model. Itraconazole Nanocapsules continues to follow model having r2 value has been 0.937, 0.399, 0.899, 0.785 & m value has been 1593, 0.061, 11409, 2.560. The discharge of drug out from Nanocapsules increased up of about 45 mints. Itraconazole loaded as for ethyl cellulose & HPMC Nanocapsules have been able to prepare below optimum condition and it display great discharge characteristic features

    A Hybrid Filter with Impulse Detection for Removal of Random Valued Impulse Noise from Colour Videos

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    This paper presents a three dimensional hybrid filter to remove random valued impulse noise from colour video sequences. The switching median technique is utilized to protect noise free isolated pixels from filtering so as to avoid blurring of frames. The restoration of noisy pixels is done by brightness information obtained from median filtering and chromaticity information is obtained from vector directional filtering. This hybrid filter is applied in three dimensional sliding window where spatial as well as temporal information about neighbourhood is available for restoration of frame under consideration. Only noise free pixels of three dimensional sliding window are used for restoration of frame under consideration. Simulation results show that the proposed three dimensional hybrid filter yields superior performance in comparison to other filtering method

    Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma

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    A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.29-year-old Hispanic woman presented to the clinic with complaints of abdominal pain, nausea, fatigue, and constipation. Laboratory tests indicated the presence of iron deficiency anemia and transaminitis. Imaging evaluation revealed marked hepatomegaly with multiple hepatic metastases and pelvic lymphadenopathy. Biopsy of the hepatic lesions showed adenocarcinoma positive for pan-cytokeratin, CMA5.2, villin, and CDX2. She was positive for tumor markers CA 19-9, CA-125, and CEA. Upon further evaluation, she was found to have colorectal cancer positive for KRAS and BRAF mutations. Unfortunately, her disease progressed rapidly and she expired within 3 months from the time of her first diagnosis. KRAS and BRAF mutations are rare enough to be considered virtually mutually exclusive but coexistent mutations appear to be a distinct molecular and clinical subset with aggressive course of illness, which is in dire need of new treatment strategies. Panitumumab and Cetuximab are approved for patients with wild type KRAS CRC. Vemurafenib is a potent inhibitor of the kinase domain in mutant BRAF and its use in BRAF mutated colon cancer remains to be well established. Our report highlights the need to obtain tissue samples from these patients for analysis and to evaluate the benefit of Vemurafenib in colorectal cancers

    Moyamoya disease: A case report with typical magnetic resonance imaging findings

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    Moyamoya disease is an idiopathic non-progressive, non-atherosclerotic, and non-inflammatory vasculo-occlusive disease commonly affecting the supraclinoid internal carotid artery with resultant secondary changes which may include infarcts, ischemia, and multiple collaterals within the brain. The term Moyamoya disease is usually reserved for the idiopathic and rarely familial condition where etiology is not known, whereas the term Moyamoya syndrome is reserved for those conditions where etiology is known. Here, we present the case report of a Moyamoya disease and magnetic resonance imaging (MRI) findings with the review of the MRI features

    Trichilemmal cysts of scalp: Imaging findings

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    A trichilemmal cyst is a cystic lesion that forms from the hair follicle. They are also known as Wens. They are smooth nodular mobile swellings of the scalp which may be tender or non-tender and may run in families. Usually multiple, they are common in the occipital scalp region but can also occur in chest, abdomen, back, vulva, and pubis. Here, we present the case report of a 45-year-old woman with multiple trichilemmal cysts of the scalp

    ANALYTICAL INVESTIGATING DIE CASTING PROCESS PARAMETERS TO IDENTIFY THE OPTIMIZED LEVELS USING TAGUCHI METHODS FOR DESIGN OF EXPERIMENT (DOE)

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    As population increases with the increasing in demand for producing the plastic products in different and sizes with high precision. A case study on plastic electrical switch box is considered to investigate on producing best quality of products to satisfy the demands from the customers. In this thesis, the focus on the optimization of process parameters (temperature, pressure, time) is carried out for injection moulding machine. Quality of characteristic (shrinkage) of the injection moulding product is made by polycarbonate material is calculated by using minitab software for the data obtained. Comparison of the experimental data and analytical results show that there is no significant difference in artificial neural network, and taguchi method was used confidently. An analytical approach is (cfd) discussed by using ansys software and the model of component design, cooling profile, assembling, runner and gate location is done in 3d modelling software creo
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