Reaction-Diffusion System in a Vesicle with Semi-Permeable Membrane

We study the Schloegl model in a vesicle with semi-permeable membrane. The diffusion constant takes a smaller value in the membrane region, which prevents the outflow of self-catalytic product. A nonequilibrium state is stably maintained inside of the vesicle. Nutrients are absorbed and waste materials are exhausted through the membrane by diffusion. It is interpreted as a model of primitive metabolism in a cell.Comment: 8 pages, 6 figure

One-pot synthesis, crystallization and deracemization of isoindolinones from achiral reactants

The synthesis, crystallization, and complete solid-state deracemization of isoindolinones was realized in one pot simply by grinding achiral reaction components in a suitable solvent with an achiral catalyst. Previously, this concept was applied to a reversible reaction, but herein we showed that it could also be used in combination with reactions in which product formation is irreversible. A controlled final configuration of the product was obtained by using small amounts of chiral additives or seed crystals of the product

On the Government’s Protection of Citizens’ Right to Know

本文讨论的是政府对于公民知情权的保护。文章主要分为三个部分：政府保护公民知情权的必要性、政府如何来保护公民的知情权以及我国政府保护公民知情权的现状和完善建议。文章由前言、第一章、第二章、第三章和结语组成。第一章论述政府保护公民知情权的必要性。本章分为两部分：政府为什么要保护公民的知情权和为什么是由政府来承担公民知情权的保护义务。信息失灵是信息社会信息不充分和信息占有不公平的现象。信息失灵的存在是不可避免的，同时信息失灵影响到了信息社会的各个方面，造成了信息社会信息资源利用的无效率和信息社会的不公平和不便利。这在一定程度上催生了公民对于知情权利的渴求，所以政府保护公民知情权也是政府解决信息社会信...The article discusses the government’s protection on citizen’s right to know. It contains three parts: the necessities for the government to protect citizens’ right to know, how to protect the right to know, the present situation and the perfection of our government’s protection mechanisms. It consists of the preface、chapter1、chapter2、chaper3 and the conclusion. Chapter 1 describes the nec...学位：法律硕士院系专业：法学院法律系_法律硕士(JM)学号：20040817

Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome: Alterations in composition and diversity of the intestinal microbiota in D-IBS

The intestinal microbiota has been implicated in the pathophysiology of Irritable Bowel Syndrome (IBS). Due to the variable resolutions of techniques used to characterize the intestinal microbiota, and the heterogeneity of IBS, the defined alterations of the IBS intestinal microbiota are inconsistent. We analyzed the composition of the intestinal microbiota in a defined subgroup of IBS patients (diarrhea-predominant IBS, D-IBS) using a technique that provides the deepest characterization available for complex microbial communities

Requests On E-Mail: a Cross-Cultural Comparison

This study investigates differences in request e-mails written in English by Chinese English learners and native American English speakers The results show that while Chinese English learners treat e-mail communications like either formal letters or telephone conversations, native American English speakers regard e-mail communications as closer to written memos It was also found that although the native American English speakers structure their e-mail request messages in a rather direct sequence, the linguistic forms they employ to express their requests are more indirect In contrast, the Chinese English learners structure their request messages in an indirect sequence, but the linguistic forms they use to realize their requests are more direct Given this contrast, it is not surprising that some of the request samples written by Chinese English learners were judged as very impolite by the native English speaking evaluators in this study The findings of this study thus demonstrate the importance of studying requests within the overall discourse in which they occur. Studying only the linguistic forms used in phrasing the request itself, as in the studies conducted by Blum-Kulka et al (1989), cannot provide us with a full picture of the cultural differences inherent in making requestsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69055/2/10.1177_003368829802900206.pd

Comparison of established and emerging biodosimetry assays

Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric chromosome assay (DCA) and cytokinesis-block micronucleus assay (CBMN) in comparison to the emerging γ-H2AX foci and gene expression assays for triage mode biodosimetry and radiation injury assessment. Coded blood samples exposed to 10 X-ray doses (240 kVp, 1 Gy/min) of up to 6.4 Gy were sent to participants for dose estimation. Report times were documented for each laboratory and assay. The mean absolute difference (MAD) of estimated doses relative to the true doses was calculated. We also merged doses into binary dose categories of clinical relevance and examined accuracy, sensitivity and specificity of the assays. Dose estimates were reported by the first laboratories within 0.3-0.4 days of receipt of samples for the γ-H2AX and gene expression assays compared to 2.4 and 4 days for the DCA and CBMN assays, respectively. Irrespective of the assay we found a 2.5-4-fold variation of interlaboratory accuracy per assay and lowest MAD values for the DCA assay (0.16 Gy) followed by CBMN (0.34 Gy), gene expression (0.34 Gy) and γ-H2AX (0.45 Gy) foci assay. Binary categories of dose estimates could be discriminated with equal efficiency for all assays, but at doses ≥1.5 Gy a 10% decrease in efficiency was observed for the foci assay, which was still comparable to the CBMN assay. In conclusion, the DCA has been confirmed as the gold standard biodosimetry method, but in situations where speed and throughput are more important than ultimate accuracy, the emerging rapid molecular assays have the potential to become useful triage tools