60 research outputs found

    Reconfigurable nested ring-split ring transmitarray unit cell employing the element rotation method by microfluidics

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    A continuously tunable, circularly polarized X-band microfluidic transmitarray unit cell employing the element rotation method is designed and fabricated. The unit cell comprises a double layer nested ring-split ring structure realized as microfluidic channels embedded in Polydimethylsiloxane (PDMS) using soft lithography techniques. Conductive regions of the rings are formed by injecting a liquid metal (an alloy of Ga, In, and Sn), whereas the split region is air. Movement of the liquid metal together with the split around the ring provides 360° linear phase shift range in the transmitted field through the unit cell. A circularly polarized unit cell is designed to operate at 8.8 GHz, satisfying the necessary phase shifting conditions provided by the element rotation method. Unit cell prototypes are fabricated and the proposed concept is verified by the measurements using waveguide simulator method, within the frequency range of 8-10 GHz. The agreement between the simulation and measurement results is satisfactory, illustrating the viability of the approach to be used in reconfigurable antennas and antenna arrays. © 2015 IEEE

    A microchip optomechanical accelerometer

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    The monitoring of accelerations is essential for a variety of applications ranging from inertial navigation to consumer electronics. The basic operation principle of an accelerometer is to measure the displacement of a flexibly mounted test mass; sensitive displacement measurement can be realized using capacitive, piezo-electric, tunnel-current, or optical methods. While optical readout provides superior displacement resolution and resilience to electromagnetic interference, current optical accelerometers either do not allow for chip-scale integration or require bulky test masses. Here we demonstrate an optomechanical accelerometer that employs ultra-sensitive all-optical displacement read-out using a planar photonic crystal cavity monolithically integrated with a nano-tethered test mass of high mechanical Q-factor. This device architecture allows for full on-chip integration and achieves a broadband acceleration resolution of 10 \mu g/rt-Hz, a bandwidth greater than 20 kHz, and a dynamic range of 50 dB with sub-milliwatt optical power requirements. Moreover, the nano-gram test masses used here allow for optomechanical back-action in the form of cooling or the optical spring effect, setting the stage for a new class of motional sensors.Comment: 16 pages, 9 figure

    General model with experimental validation of electrical resonant frequency tuning of electromagnetic vibration energy harvesters

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    This paper presents a general model and its experimental validation for electrically tunable electromagnetic energy harvesters. Electrical tuning relies on the adjustment of the electrical load so that the maximum output power of the energy harvester occurs at a frequency which is different from the mechanical resonant frequency of the energy harvester. Theoretical analysis shows that for this approach to be feasible the electromagnetic vibration energy harvester’s coupling factor must be maximized so that its resonant frequency can be tuned with the minimum decrease of output power. Two different-sized electromagnetic energy harvesters were built and tested to validate the model. Experimentally, the micro-scale energy harvester has a coupling factor of 0.0035 and an untuned resonant frequency of 70.05 Hz. When excited at 30 mg, it was tuned by 0.23 Hz by changing its capacitive load from 0 to 4000 nF; its effective tuning range is 0.15 Hz for a capacitive load variation from 0 to 1500 nF. The macro-scale energy harvester has a coupling factor of 552.25 and an untuned resonant frequency of 95.1 Hz and 95.5 Hz when excited at 10 mg and 25 mg, respectively. When excited at 10 mg, it was tuned by 3.8 Hz by changing its capacitive load from 0 to 1400 nF; it has an effective tuning range of 3.5 Hz for a capacitive load variation from 0 to 1200 nF. When excited at 25 mg, its resonant frequency was tuned by 4.2 Hz by changing its capacitive load from 0 to 1400 nF; it has an effective tuning range of about 5 Hz. Experimental results were found to agree with the theoretical analysis to within 10%

    Detecting imipenem resistance in Acinetobacter baumannii by automated systems (BD Phoenix, Microscan WalkAway, Vitek 2); high error rates with Microscan WalkAway

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    <p>Abstract</p> <p>Background</p> <p>Increasing reports of carbapenem resistant <it>Acinetobacter baumannii </it>infections are of serious concern. Reliable susceptibility testing results remains a critical issue for the clinical outcome. Automated systems are increasingly used for species identification and susceptibility testing. This study was organized to evaluate the accuracies of three widely used automated susceptibility testing methods for testing the imipenem susceptibilities of <it>A. baumannii </it>isolates, by comparing to the validated test methods.</p> <p>Methods</p> <p>Selected 112 clinical isolates of <it>A. baumanii </it>collected between January 2003 and May 2006 were tested to confirm imipenem susceptibility results. Strains were tested against imipenem by the reference broth microdilution (BMD), disk diffusion (DD), Etest, BD Phoenix, MicroScan WalkAway and Vitek 2 automated systems. Data were analysed by comparing the results from each test method to those produced by the reference BMD test.</p> <p>Results</p> <p>MicroScan performed true identification of all <it>A. baumannii </it>strains while Vitek 2 unidentified one strain, Phoenix unidentified two strains and misidentified two strains. Eighty seven of the strains (78%) were resistant to imipenem by BMD. Etest, Vitek 2 and BD Phoenix produced acceptable error rates when tested against imipenem. Etest showed the best performance with only two minor errors (1.8%). Vitek 2 produced eight minor errors(7.2%). BD Phoenix produced three major errors (2.8%). DD produced two very major errors (1.8%) (slightly higher (0.3%) than the acceptable limit) and three major errors (2.7%). MicroScan showed the worst performance in susceptibility testing with unacceptable error rates; 28 very major (25%) and 50 minor errors (44.6%).</p> <p>Conclusion</p> <p>Reporting errors for <it>A. baumannii </it>against imipenem do exist in susceptibility testing systems. We suggest clinical laboratories using MicroScan system for routine use should consider using a second, independent antimicrobial susceptibility testing method to validate imipenem susceptibility. Etest, whereever available, may be used as an easy method to confirm imipenem susceptibility.</p

    Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

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    Antimicrobial effects of two anaesthetic agents: Dexmedetomidine and midazolam

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    Some anaesthetic agents are known to inhibit microbial growth. The aim of this in vitro study was to investigate possible antimicrobial effects of two frequently used agents in intensive care units, dexmedetomidine and midazolam. Antimicrobial effect was tested on Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa by broth microdilution method. Midazolam showed inhibitor and bactericidal effect on S. aureus at concentrations 256 ”g.ml-1 and 512 ”g.ml-1 respectively and on E. faecalis at concentrations 128 ”g.ml-1 and 256 ”g.ml-1. Dexmedetomidine demonstrated inhibitor effect on S. aureus, E. coli and P. aeruginosa at concentrations 32 ”g.ml-1, 16 ”g.ml-1 and 16 ”g.ml-1 respectively. Midazolam had inhibitor and bactericidal effects on S. aureus and E. faecalis. Dexmedetomidine had only inhibitor effects on S. aureus, E. coli and P. aeruginosa. Further studies are needed to determine the antimicrobial mechanisms and clinical applications
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