Управление многоканальными системами по Н² и Н∞ критериям

Розроблена методика синтезу регуляторів багатоканальних систем, що працюють за принципом грубого та точного керування, оптимальних за Н² и Н∞ критеріями. Методика дозволяє синтезувати багатоканальні системи високої точності та низької чутливості до зміни параметрів і структури моделей об’єктів керування та зовнішніх збурень багатоканальних систем. Наведено приклад застосування розробленої методики для синтезу двоканальної системи, що стежить

Комплекс геофизических исследований скважин для построения профиля притока нефти на Киев-Еганском месторождении нефти (Томская область)

Объектом исследования является добывающая скважина Киев-Еганского месторождения нефти. Приводится обзор геолого-геофизической изученности месторождения, анализ результатов геологических и геофизических работ. Представляется выбранный комплекс геофизических методов для определения профиля притока скважины. Определен объем затрат на выполнение комплекса, разработаны мероприятия по охране окружающей среды и безопасности в чрезвычайных ситуациях.The object of research is a exploitation well of the Kiev-Yeganskoye oil field (Tomsk region). A review of the geological and geophysical field exploration, analysis of geological and geophysical work results. The selected set of geophysical methods for determining the inflow profile. The amount of costs for the complex implementation was determined, measures were taken to protect the environment and safety in emergency situations

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+-activated large-conductance K+ channels in endothelial cells

Lysophospholipids are known to serve as intra- and extracellular messengers affecting many physiological processes. Lysophosphatidylinositol (LPI), which is produced in endothelial cells, acts as an endogenous agonist of the orphan receptor, G protein-coupled receptor 55 (GPR55). Stimulation of GPR55 by LPI evokes an intracellular Ca2+ rise in several cell types including endothelial cells. In this study, we investigated additional direct, receptor-independent effects of LPI on endothelial large-conductance Ca2+ and voltage-gated potassium (BKCa) channels. Electrophysiological experiments in the inside-out configuration revealed that LPI directly affects the BKCa channel gating properties. This effect of LPI strictly depended on the presence of Ca2+ and was concentration-dependent, reversible, and dual in nature. The modulating effects of LPI on endothelial BKCa channels correlated with their initial open probability (Po): stimulation at low Po (<0.3) and inhibition at high Po levels (>0.3). In the whole-cell configuration, LPI in the pipette facilitated membrane hyperpolarization in response to low (0.1–2 μM) histamine concentrations. In contrast, LPI counteracted membrane hyperpolarization in response to supramaximal cell stimulation with histamine. These results highlight a novel receptor-independent and direct bidirectional modulation of BKCa channels by LPI on endothelial cells. We conclude that LPI via this mechanism serves as an important modulator of endothelial electrical responses to cell stimulation

Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216

Gesamtkonzept zur Ermittlung der seismischen Vulnerabilität von Bauwerken am Beispiel unterirdischer Rohrleitungen

Earthquakes are one of the natural phenomena which present a high risk for the safety of human lives and man-made structures. Since the early history of mankind catastrophic earthquakes have occurred. Damages of buildings as well as faults at the ground surface are the most spectacular consequences and can be easily observed. In the last century the pipe networks to ensure the supply of the population have been greatly extended. Therefore more underground infrastructure has been damaged due to earthquakes. These damages are generally less spectacular, yet determine the amount of consequential damage of an earthquake (e.g. by the fire water supply) and the possibility to supply the population after an earthquake effectively and sufficiently. Within the present work an overall concept for evaluating the seismic vulnerability of structures exemplified through underground pipelines is developed. With it the following questions are to be answered: - How big is the seismic vulnerability of existing pipelines? The investigations necessary to answer this question shall be carried out on three different levels of accuracy. - How big are the financial consequences that are to be expected? This question is especially important for insurance companies and the budgeting of public authorities. The computations on level I are based on simple empirical relationships between seismic action and damage rate. Although such approaches are often used in practice to determine earthquake scenarios of whole regions the results are reliable only for areas which have been considered for the identification of these empirical relationships. On level II analytical relationships between the seismic action and the mechanical reaction of the pipeline (stresses, strains, etc.) are employed. Even more accurate are on level III the finite element simulations to analyse structures under seismic load. Here the emphasis is on the modelling of the pipeline and the seismic action while the soil is represented in a simplified way. Based on parameter studies the reliability of the different methods is investigated and using sensitivity analyses the relevant input parameters for the damage are identified. Since the required input values for the calculations on all three levels are subject to partly large variations all methods have been extended by the possibility of a probabilistic calculation to take into account these variations. The computations on level II and III are followed in a second step by the determination of the damage rate from the mechanical response of the structure. For this purpose as well as for the following calculation of the financial losses failure indices have been developed within the present work. With them finally the annual insurance premium of a pipeline is calculated based on confidence intervals. Since all types of structures are affected by the seismic hazard it is very important to build up a common platform to link the investigations of different building types, e.g. for the development of regional scenarios. Additionally this ensures the sustainability and long term availability of results from different research areas. Within this work such a central web-based platform has been used for the first time for seismic vulnerability assessments and all methods implemented within this work are accessible via this platform