246 research outputs found

    Π’he transformation of the higher education in Ukraine in the context of the globalization of the world education market

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    Analyzed the modern features of the global market, defines the key directions of forming an effective educational policy in Ukraine and ways to accelerate the export of educational services.ΠŸΡ€ΠΎΠ°Π½Π°Π»Ρ–Π·ΠΎΠ²Π°Π½ΠΎ сучасні особливості Ρ€ΠΎΠ·Π²ΠΈΡ‚ΠΊΡƒ світового Ρ€ΠΈΠ½ΠΊΡƒ послуг, Π²ΠΈΠ·Π½Π°Ρ‡Π΅Π½ΠΎ ΠΊΠ»ΡŽΡ‡ΠΎΠ²Ρ– напрямки формування Π΅Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡ— ΠΎΡΠ²Ρ–Ρ‚Π½ΡŒΠΎΡ— ΠΏΠΎΠ»Ρ–Ρ‚ΠΈΠΊΠΈ Π² Π£ΠΊΡ€Π°Ρ—Π½Ρ– Ρ‚Π° ΡˆΠ»ΡΡ…ΠΈ Π°ΠΊΡ‚ΠΈΠ²Ρ–Π·Π°Ρ†Ρ–Ρ— Скспорту освітніх послуг.ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ соврСмСнныС особСнности развития ΠΌΠΈΡ€ΠΎΠ²ΠΎΠ³ΠΎ Ρ€Ρ‹Π½ΠΊΠ° услуг, ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΊΠ»ΡŽΡ‡Π΅Π²Ρ‹Π΅ направлСния формирования эффСктивной ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π² Π£ΠΊΡ€Π°ΠΈΠ½Π΅ ΠΈ ΠΏΡƒΡ‚ΠΈ Π°ΠΊΡ‚ΠΈΠ²ΠΈΠ·Π°Ρ†ΠΈΠΈ экспорта ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… услуг

    Mineral-petrochemical wallrock alteration of rocks in Bericul gold-ore deposit (Kuznetsk Alatau)

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    The distribution of mineral associations in near-veined zonal propylite-beresite metasomatic columns of mesothermal Bericul gold-ore deposit was analyzed. However, the polymineral composition in the inner (axial and adjacent with it rear) zones is inconsistent to the existing metasomatic column theoretical model. According to Korzhinskii metasomatic zoning theory, implied monomineral (quartz) and binary-mineral (quartz, sericite) compositions are characteristic of axial and rear zones, respectively. In common with above-mentioned facts, the zoning formation of differential component mobility is influenced by two additional factors: counter diffusion of components from fractured fluids into pores and diffusion mechanism of mass transfer it's from pores fluids into fractured of rock-fluid systems

    Model of Optimal Planning of Development of State Information Systems in the Face of Multicriteria and Uncertainty

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    Information technology has become an integral part of the activities of authorities. One of the main elements of the ecosystem of the digital economy, including the infrastructure of the electronic government of the Russian Federation, are federal and regional state information systems. Only in St. Petersburg, as in the subject of the Russian Federation, 68 GISs operate, a limited budget determines the need for their rational distribution, taking into account the importance, complexity, impact on other systems. This determines the need for planning the distribution of costs of the city budget for their creation, maintenance and modernization. The task of defining such a plan can be considered as a decision making task. The article considers the issue of developing a generalized mathematical model of optimal planning under conditions of multicriteria and uncertainty

    Wave-vector dependent intensity variations of the Kondo peak in photoemission from CePd3_3

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    Strong angle-dependent intensity variations of the Fermi-level feature are observed in 4d - 4f resonant photoemission spectra of CePd3_3(111), that reveal the periodicity of the lattice and largest intensity close to the Gamma points of the surface Brillouin zone. In the framework of a simplified periodic Anderson model the phenomena may quantitatively be described by a wave-vector dependence of the electron hopping matrix elements caused by Fermi-level crossings of non-4f-derived energy bands

    Calculation of Field Characteristics in Periodic Nanostructures from Composite Elements with Activated Plasmon Modes

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    Modeling of the electromagnetic field of the optical frequency in periodic structures composed of parallel conducting nanorods as well as composite spherical nanoparticles with an excitonogenic envelope in hexagonal 2d-lattices - in the quasistatic approximation and the FDTD method. The qualitative agreement of these approaches is shown when calculating field characteristics in lattices of cylindrical elements

    New modern ways of the development of the higher education in Ukraine

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    The state and terms of the investment providing of higher educational establishments have been analyzed. The basic tendencies of the forming of the investment process are certain in the field of higher education. The role of the investments is shown in upgrading of the educational services in the system of the higher education

    CeFePO: f-d hybridization and quenching of superconductivity

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    Being homologue to the new, Fe-based type of high-temperature superconductors, CeFePO exhibits magnetism, Kondo and heavy-fermion phenomena. We experimentally studied the electronic structure of CeFePO by means of angle-resolved photoemission spectroscopy. In particular, contributions of the Ce 4f-derived states and their hybridization to the Fe 3d bands were explored using both symmetry selection rules for excitation and their photoionization cross-section variations as a function of photon energy. It was experimentally found - and later on confirmed by LDA as well as DMFT calculations - that the Ce 4f states hybridize to the Fe 3d states of d_{3z^2-r^2} symmetry near the Fermi level that discloses their participation in the occurring electron-correlation phenomena and provides insight into mechanism of superconductivity in oxopnictides.Comment: 5 pages, 3 figure

    Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy.

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    Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM receptor dystroglycan (Dg). Remarkably, among many cases of diagnosed dystroglycanopathies, only a small fraction can be linked directly to mutations in Dg or its regulatory enzymes, implying the involvement of other, not-yet-characterized, Dg-regulating factors. To advance disease diagnostics and develop new treatment strategies, new approaches to find dystroglycanopathy-related factors should be considered. The Dg complex is highly evolutionarily conserved; therefore, model genetic organisms provide excellent systems to address this challenge. In particular, Drosophila is amenable to experiments not feasible in any other system, allowing original insights about the functional interactors of the Dg complex. METHODS: To identify new players contributing to dystroglycanopathies, we used Drosophila as a genetic muscular dystrophy model. Using mass spectrometry, we searched for muscle-specific Dg interactors. Next, in silico analyses allowed us to determine their association with diseases and pathological conditions in humans. Using immunohistochemical, biochemical, and genetic interaction approaches followed by the detailed analysis of the muscle tissue architecture, we verified Dg interaction with some of the discovered factors. Analyses of mouse muscles and myocytes were used to test if interactions are conserved in vertebrates. RESULTS: The muscle-specific Dg complexome revealed novel components that influence the efficiency of Dg function in the muscles. We identified the closest human homologs for Dg-interacting partners, determined their significant enrichment in disease-associations, and verified some of the newly identified Dg interactions. We found that Dg associates with two components of the mechanosignaling Hippo pathway: the WW domain-containing proteins Kibra and Yorkie. Importantly, this conserved interaction manages adult muscle size and integrity. CONCLUSIONS: The results presented in this study provide a new list of muscle-specific Dg interactors, further analysis of which could aid not only in the diagnosis of muscular dystrophies, but also in the development of new therapeutics. To regulate muscle fitness during aging and disease, Dg associates with Kibra and Yorkie and acts as a transmembrane Hippo signaling receptor that transmits extracellular information to intracellular signaling cascades, regulating muscle gene expression
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