Complementary feeding with traditional and baby led weaning (BLW) methods - assessment of selected aspects of infant's diet

Background: Infant nutrition is a topic of constant debate between parents and doctors. The recommendations themselves have been modified several times over the past 6 decades. Baby Led Weaning (BLW) method is gaining more and more popularity in infant nutrition during the period of expanding the infant menu. The main aim of the study was to evaluate selected aspects of dietary expansion in a group of their children, taking into account dietary expansion with the use of the traditional method and the BLW method. Material and method: An exploratory cross-sectional study was conducted in December 2021-January 2022 among a randomly selected sample of 523 mothers of children in infancy aged up to 12 months. Data for the study were collected anonymously using the CAWI method. The information collected from 500 women was considered for the final data analysis taking into account the inclusion and exclusion criteria. Results: 66.6% of the women surveyed (N=333) stated that their child is or was fed breast milk during the first six months. The child's diet was most often expanded with complementary meals after 6 months of age. This answer was indicated by 58.8% of respondents (N=294). 85.6% of the surveyed women (N=428) first introduced or intend to introduce vegetables to their diet. 13% of the respondents (N=65) introduced or planned to introduce vegetables and fruit at the same time. In the studied group of mothers the BLW method was not known or not used by 7 mothers (1.4%), 343 mothers used or intended to use the BLW method (68.6%), whereas 150 women knew the BLW method (30.0%), but did not use it or did not intend to use it during the expansion of their child's diet. Conclusions: The majority of mothers surveyed used the BLW method during the expansion of their children's diet, accepting the principle that it is the child who decides whether and how much to eat, and the parent who decides what and when the child eats

Data regarding particle size distribution, thermal properties and gaseous phase hydration of co-milled solid dispersions composed of tadalafil and Soluplus

A mechanical activation of the solid particles upon high-energy ball milling may considerably change the physicochemical properties of pharmaceutical compounds, including the morphology, particle size distribution, thermal properties, and surface interactions with water vapour upon gaseous phase hydration. Assessment of these changes is crucial for optimizing the manufacturing process of enabling drug products. In this article, we provide a detailed characterization of binary co-milled solid dispersions composed of tadalafil and Soluplus using a laser diffraction method, differential scanning calorimetry (DSC), gravimetric measurements and solid state (1)H- NMR spectroscopy. The data presented in this article is directly related to our previously published research article. They complement information on the impact that both formulation and process variables may have on the properties of these binary powder formulations

Health risks of environmental exposure to microplastics

Plastics are materials widely used in all sectors. The subject of interest in recent years has become so-called microplastics, whose composition and structure are causing new environmental hazards. The presence and accumulation of microplastics in the environment threaten the ecological balance, the water environment, food sustainability and safety, and ultimately human health. Human exposure to microplastics is primarily through the oral route, so the main source of human exposure to microplastics is diet. Despite many studies focusing on microplastic contamination in seafood, fish, and shellfish, estimating total human exposure to microplastics via the oral route is difficult, due to the lack of research on other foods in this area. The risks to human health from inhaling microplastics remain unclear. According to the WHO, there is no reliable evidence of the harmful effects of microplastic on the human body, but the phenomenon requires further research. Likely health effects of human exposure to microplastic include respiratory and gastrointestinal effects, oxidative stress, and cancer. There is a need to raise public awareness about environmental exposure to microplastics and effective waste management

RADIal versus femoral approach for percutaneous coronary interventions in patients with Acute Myocardial Infarction (RADIAMI): A prospective, randomized, single-center clinical trial

Background: The transradial approach for percutaneous coronary intervention (PCI) seems to be superior to transfemoral. The safety and efficacy of transradial approach for PCI in acute myocardial infarction is not well-established. Methods: Hundred patients with acute myocardial infarction qualified to PCI were randomly assigned to transradial (group I; n = 50) and transfemoral (group II; n = 50) approaches. Results: PCI was successful for almost all patients, except one from group II. There were no significant differences between groups in X-ray exposition, volume of contrast and total procedure duration. Small but significant elongation of door to stent time in group I was caused mostly by a longer time between beginning of procedure and arterial sheath introduction. Major bleeding complications occurred in three patients from group I and seven from group II. There were no significant differences observed between the two groups. Time to ambulation in group I was significantly shorter then in group II (22.6 ± 10.3 h vs. 34.7 ± 34.6 h; p = 0.003). Conclusions: The transradial approach for PCI in acute myocardial infarction has the same efficacy as transfemoral. There are no differences in total procedure duration, X-ray exposition or volume of contrast between the two approaches. A longer time from the patient’s admission to the individual stages of the PCI procedure in group I was mostly due to the longer times of the initial stages of the procedure. The use of transradial approach reduces the time to ambulation and allows rehabilitation to begin sooner. In both groups, bleeding complications occurred rarely

Risk factors for reoperation after surgical treatment for degenerative spinal disease in Poland: a nationwide retrospective study of 38,953 hospitalisations

Introduction. Degenerative spinal disease (DSD) is one of the most common musculoskeletal conditions and a leading cause of sickness absence. It also contributes significantly to the global burden of disease. The aim of this study was to assess the frequency of reoperation after surgical treatment of DSDs in Poland, and to identify risk factors for reoperation.Material and methods. A retrospective analysis of hospitalisations for DSD in 2018 that were reported to Poland’s National Health Fund (NHF) was performed. Reoperations reported within 365 days of hospital discharge were identified. Demographic factors and multimorbidities were included in the analysis. A logistic regression model was then performed to assess risk factors for reoperations.Results. In 2018, 38,953 surgical hospitalszations for DSD were reported. A total of 3,942 hospitalised patients (10.12%) required reoperation within 365 days. Patients requiring reoperation were predominantly female (female-to-male ratio 1.34:1) and elderly (mean age of reoperated patients 56.66 years, mean age of other patients 53.24). The percentage reoperated upon correlated with multiple diseases (from 8.81% in the group of patients without comorbidities to 15.31% in the group of patients with three or more comorbidities). The risk of reoperation was most increased by comorbid depression, neurological diseases, obesity, and older age. The risk of reoperation was reduced by instrumented spinal surgery, surgery in a neurosurgical unit, and hospitalisations other than same-day surgery.Conclusions. Reoperations within a year after DSD surgical treatment are common. Identifying risk factors for reoperation, including those related to the presence of comorbidities and the phenomenon of multimorbidity, can be an important tool in reducing reoperation rates

Modelowy projekt prewencji chorób układu krążenia na przykładzie doświadczeń Programu SOPKARD. Część pierwsza

Choroby serca i naczyń są najczęstszą przyczyną zgonów w Polsce. W 2001 roku umieralność z powodu chorób układu krążenia wyniosła 48%, a umieralność przedwczesna z tego samego powodu 2,5-krotnie przekroczyła odpowiednie wskaźniki w „starej” Unii Europejskiej. Najważniejszymi czynnikami odpowiedzialnymi za tak dużą liczbę zgonów są zawały serca i udary mózgu. Znaczna częstość incydentów kardiologicznych i neurologicznych wynika głównie z dużego rozpowszechnienia oraz małej wykrywalności i skuteczności leczenia czynników ryzyka sercowo-naczyniowego. Poprawa obecnej sytuacji epidemiologicznej wymaga rozpoczęcia odpowiednich działań profilaktycznych, zanim rozwiną się zaburzenia lub ich szybkiego rozpoznawania i leczenia.W niniejszej pracy, na przykładzie projektu SOPKARD, przedstawiono schemat optymalnego w polskich warunkach programu przesiewowego, opartego na najnowszych standardach diagnostycznych europejskich towarzystw naukowych. Modelowy projekt można wdrożyć zarówno w małych miejscowościach w postaci jednoośrodkowego centrum prewencji, jak i w dużych miastach, angażując do współpracy wiele ośrodków lub grupy lekarzy rodzinnych