Fuzzy simulation of forest road surface parameters

The problem of construction of forest roads with the use of local low-strength substandard materials and industrial waste is considered. To solve the problem, the primary task is to develop a method for estimating the parameters of road surfaces taking into account the conditions of uncertainties in the data. This technique allows us to reasonably clarify some of the regulatory parameters and improve the technology of construction of forest roads, which was the goal of the work. To formalize the task, experimental studies were performed and on the basis of these results, the statement of the task of fuzzy derivation of the function for estimating the bearing capacity of the coating was performed. The synthesis of the output function is performed by means of Matlab. © 2019 IOP Publishing Ltd. All rights reserved

Efficiency improvement of forest machinery exploitation

The purpose of this work was to develop a model of the interaction process between the wheeled forwarder and the soil of the cutting area, which allows evaluating the influence of soil conditions, the parameters of the wheeled forwarder, as well as load and number of cycles of its application, on the indicators of resistance and adhesion of the forwarder to the traction surface. Modeling results for 3-and 4-Axle forest machines with different load levels showed that for different soil categories, types of bodies, and tire sizes. The results of the approximation analysis enabled the derive of calculation formulas for estimating the propulsive coefficient and rut depth after the first passage depending on the values of load-bearing capacity, body load coefficient, wheel width, and soil deformation module. The proposed model can be used at laying down the skidding roads and its optimization not only in economic terms but also with respect to the environment as intensive harvesting operations lead to extensive soil destructions. The practical application of the results is expressed in increased performance capacities of wood skidding operations and minimization of costs for restoring the productivity of forest area. © 2020 Polish Society of Technical Diagnostics. All rights reserved

Predicting the Passability of Wheeled Tractors

Assessment of the tractor's passability plays an essential role in determining its capability to move under certain conditions. However, the operation of forest machinery may lead to soil deformation and degradation of its mechanical properties. Consequently, this study aims to develop a mathematical model for the tractor's crosscountry capability assessment and its impact on the soil. A predictive model was created as part of the study, which depends on the soil and the forwarder parameters. Some high-correlation dependencies of deformation modulus and cone index, specific tractive force, internal friction angle, and shear modulus on these parameters were established. The developed model can be used to analyze changes in rut depth and soil compaction factors after multiple tractor passages. Soil moisture content and temperature can influence the deformation rate, as drier and warmer soils tend to deform much faster. Furthermore, the proposed model can analyze the impact of forestry and agricultural machinery on soils. © 2022, Mathematical Modelling of Engineering Problems. All Rights Reserved

NEW ASPECTS OF THE USE OF PROTEIN TISSUE-SPECIFIC MARKERS IN THE ESTIMATION OF SEVERITY OF COMMUNITY-ACQUIRED PNEUMONIA

The purpose of the study was to assess the associations of proteins of pulmonary surfactants A (SP-A) and D (SP-D) with the severity of community-acquired pneumonia. Material and methods. A survey of 188 patients diagnosed with community-acquired pneumonia (CAP). The average age of the examined patients was 54.3 ± 16.5 years (M ± SD). In 102 patients (54.3 %) severe CAP was verified. All patients underwent clinical, functional, diagnostic and laboratory studies. Results and discussion. It was determined that SP-A and SP-D content was significantly higher in patients with severe CAP compared to patients with a mild course of this disease. The direct association of severe CAP with an elevated SP-AP level, directly associated with an increase in the concentration of C-reactive protein in the blood and erythrocyte sedimentation rate, have been confirmed in early studies. Using partial correlation analysis, it was established that the severe course of CAP is directly related to SP-A (r = 0.221; p = 0.003) and SP-D content (r = 0.262; p < 0.001) regardless of age, smoking, and body weight. Thus, direct associations of SP-A and SP-D with a severe course of CAP reflect the high pathogenetic significance of these protective factors in infectious lung damage

ИССЛЕДОВАНИЕ УРОВНЯ ЖИРНЫХ КИСЛОТ МЕМБРАН ЭРИТРОЦИТОВ И СЫВОРОТКИ КРОВИ У ПАЦИЕНТОВ С КОЛОРЕКТАЛЬНЫМ РАКОМ Г. НОВОСИБИРСКА

The objective is to measure the level of fatty acids in erythrocyte membranes and serum of patients with colorectal cancer.Materials and methods. The study group included 100 patients with diagnosed colorectal cancer (57 men and 43 women). The control group included 24 reasonably healthy people (14 men and 10 women) matched for age and sex, without malignant cancers or manifested pathology of the internal organs.Results. Decreased levels of saturated, monounsaturated fatty acids and increased levels of polyunsaturated fatty acids (PUFAs) in erythrocyte membranes and serum (p <0.0001–0.05) were observed. The levels of omega-3 PUFAs in colorectal cancer exceeded the levels in healthy individuals both in erythrocyte membranes and in serum; for omega-6 PUFAs only a trend was observed. At the same time, the ratio of omega-6/omega-3 PUFAs in colorectal cancer was lower than in control (p <0.0001–0.002). The state of erythrocyte membranes more significantly and for more parameters characterized differences between the groups than serum. The most discriminating parameters between patients with colorectal cancer and healthy individuals both in erythrocyte membranes and serum were the levels of C20:2;11,14 (eicosadienoic), C20:3;8,11,14 (dihomo-γ-linolenic), C20:4;5,8,11,14 (eicosatetraenoic, arachidonic), C22:5;7,10,13,16,19 (docosapentaenoic), and C22:6;4,7,10,13,16,19 (docosahexaenoic) PUFAs.Цель исследования – изучить уровень жирных кислот мембран эритроцитов и сыворотки крови у пациентов с колоректальным раком.Материалы и методы. В основную группу вошли 100 пациентов с диагностированным колоректальным раком (57 мужчин и 43 женщины). Контрольная группа включала 24 практически здоровых человека (14 мужчин и 10 женщин), не имеющих злокачественных новообразований, без манифестирующей патологии внутренних органов. Группы были сопоставимы по возрасту и полу.Результаты. Выявлены сниженные уровни насыщенных, мононенасыщенных жирных кислот и повышенные – полиненасыщенных жирных кислот (ПНЖК) в мембранах эритроцитов и сыворотке крови (p <0,0001–0,05). Уровни омега-3 ПНЖК при колоректальном раке превышали таковые у здоровых лиц как в мембранах эритроцитов, так и в сыворотке крови, для омега-6 ПНЖК выявлена лишь тенденция к повышению. При этом соотношение омега-6/омега-3 ПНЖК при колоректальном раке ниже, чем в контроле (p <0,0001–0,002). Состояние мембран эритроцитов более достоверно и по большему числу показателей, чем сыворотка крови, отражает имеющиеся различия между группами. Наиболее дискриминирующими показателями между пациентами с колоректальным раком и здоровыми лицами как в мембранах эритроцитов, так и в сыворотке крови, оказались уровни C20:2;11,14 (докодиеновой), C20:3;8,11,14 (дигомо-γ-линоленовой), C20:4;5,8,11,14 (эйкозатетраеновой, арахидоновой), C22:5; 7,10,13,16,19 (докозапентаеновой) и C22:6;4,7,10,13,16,19 (докозагексаеновой) ПНЖК

Physical activity of pregnant women as an object of a favorable course of pregnancy

The paper analyzed the effect of physical activity on the course of pregnancy. This study was conducted using the methods of questioning and analysis of medical records of pregnant women. The data we obtained confirm the importance of the fact that regular physical activity before and during pregnancy reduces the risk of developing gestational diabetes mellitus, gestational arterial hypertension and prevents the impairment of uteroplacental blood flow.В работе был проведен анализ влияния физической активности на течение беременности. Данное исследование было проведено с помощью методов анкетирования и анализа обменных карт беременных. Полученные нами данные подтверждают важность того факта, что регулярная физическая активность до и во время беременности снижает риск развития гестационного сахарного диабета, гестационной артериальной гипертензии и предотвращают нарушение маточно - плацентарного кровотока

Imported cases of tropical malaria Tyumen

This paper presents a review of the literature and conducted a retrospective analysis of the medical records of patients undergoing treatment at the Tyumen Regional Infectious Clinical Hospital. Malaria is a life-threatening infectious disease, the causative agents of which are malarial plasmodia. Infection of people occurs as a result of the bite of infected female mosquitoes of the genus Anopheles. In Russia, malaria is of an import nature; it is imported from endemic areas to the territory of the south of the Tyumen Region by employees of UTair. Thus, for the last eight years, only 33 cases of malaria have been registered in the south of the region and the city, of which: three-day 15% (n-4); oval malaria 1 % (n -1); tropical 84% (n-28). At the same time, all cases of tropical malaria in the south of the Tyumen region and the city are imported from the African continent, most often from the Congo and Sudan.В данной работе представлен обзор литературы и проведен ретроспективный анализ медицинской документации больных находящихся на лечении в ГБУЗ ТО Тюменская областная инфекционная клиническая больница'. Малярия - опасное для жизни инфекционное заболевание, возбудителями которого являются малярийные плазмодии. Заражение людей происходит в результате укуса инфицированных самок комаров рода Anopheles. В РФ малярия носит завозной характер, на территорию юга Тюменской области из эндемичных районов завозится сотрудниками компании «ЮТэйр». Так, за последние восемь лет на территории юга области и города зарегистрировано всего 33 случая малярии, из них: трехдневной 15% (n-4); овале малярия 1% (n-1); тропической 84% (n-28). При этом, все случаи тропической малярии на территорию юга Тюменской области и города завозятся с африканского континента, наиболее часто с Конго и Судана

Asymptomatic rotavirus infection: epidemiological significance, age and seasonal features

Rotavirus infection is the main cause of acute gastroenteritis in young children. The epidemiology of the disease is due to the high contagiousness, antigenic diversity of the pathogen and the activity of contact-household transmission of rotaviruses. The study was conducted on the basis of the Infectious Diseases Department of GBUZ TH OB # 3 in Tobolsk among 480 patients aged from 2 weeks to 90 years who applied for an intestinal dysbacteriosis examination. The wide spread of aspptom atic forms of RVI among the population of Tobolsk was revealed, the characteristics of infection by age groups were given. Aspptom atic forms make up the bulk of all cases of rotavirus infection, serve as a reservoir of the viral gene pool, source of new variants of the virus and play a major role in the immune selection of epidemic strains and the development of the epidemic process.Ротавирусная инфекция является основной причиной острых гастроэнтеритов у детей раннего возраста. Эпидемиология заболевания обусловлена высокой контагиозностью, антигенным разнообразием возбудителя и активностью контактно-бытовой передай ротавирусов. Исследование проводилось на базе Инфекционного отделения ГБУЗ ТО ОБ № 3 в г. Тобольске среди 480 пациентов в возрасте от 2 недель до 90 лет, обратившихся для обследования на дисбактериоз кишечника. Выявлено широкое распространение бессимптомных форм РВИ среди населения г. Тобольск, дана характеристика зараженности по возрастным группам. Бессимптомные формы составляют основную часть всех случаев ротавирусной инфекции, служат резервуаром вирусного генофонда, источником новых вариантов вируса и играют главную роль в иммунной селекции эпидемических штаммов и развитии эпидемического процесса

Clinical case of polyglandular autoimmune syndrome of type I of a child. Difficulty diagnostics

Clinical observation of polyglandular autoimmune syndrome (PAS) type I in a 10-year-old child is presented. A feature of this case was the lack of adequate drug therapy in view of the fact that the child’s mother canceled it herself. This, in turn, made it difficult to implement adequate patient management tactics. Due to the progression of the disease, the child’s condition worsened, the quality of life significantly decreased. The article discusses questions about the complexity of diagnosis and the management of patients with type I PAS.Представлено клиническое наблюдение полигландулярного аутоиммунного синдрома (ПАС) I типа у ребенка 10 лет. Особенностью данного случая явилось отсутствие адекватной медикаментозной терапии в виду того, что мать ребенка ее отменяла самостоятельно. Это, в свою очередь, затрудняло осуществление адекватной тактики ведения пациента. Ввиду прогрессирования болезни состояние ребенка ухудшалось, значительно снижалось качество жизни. В статье обсуждаются вопросы о сложности диагностики и тактике ведения пациентов с ПАС I типа