An Experimental 11.5 T Nb3Sn LHC Type of Dipole Magnet

As part of the magnet development program for the LHC an experimental 1 m long 11.5 T single aperture Nb3Sn dipole magnet has been designed and is now under construction. The design is focused on full utilisation of the high current density in the powder tube Nb3Sn. A new field optimisation has led to a different winding layout and cable sizes as compared to the reference LHC design. Another important feature of the design is the implementation of a shrink fit ring collar system. An extensive study of the critical current of the Nb3Sn cables as a function of the transverse stress on the cables shows a permanent degradation by the cabling process of about 20%, still leaving a safety margin at the operation field of 11.5 T of 15%. A revised glass/mica glass insulation system is applied which improves the thermal conductivity of the windings as well as the impregnation process considerably. This paper describes various design and production details of the magnet system as well as component test

Predictable and robust performance of a Bi-2223 superconducting coil for compact isochronous cyclotrons

The development of ever smaller medical particle accelerators is motivated by a desire to make proton therapy accessible to more patients. Reducing the footprint of particle accelerators and subsequently proton therapy facilities allows for cheaper and broader usage of proton therapy. By employing superconducting technologies for field shaping, the size of particle accelerators can be reduced further below what is possible with saturated iron. This article discusses experiments on a first-of-its-kind double pancake (DP), and an assembly of six DP coils, designed to be used as a so-called ‘flutter coil’ for a compact isochronous cyclotron for proton therapy, fabricated from high-temperature superconducting (HTS) Bi 2 − x Pbx Sr2Ca2Cu3Oy (Bi-2223) tape. The coils were mounted under pre-stress within a stainless-steel structure to maintain mechanical stability during the experiments. The critical current as a function of the temperature of both coils was measured in a conduction-cooled setup. A model describing the coils, based on tape data, was created and revealed that the measurements were in excellent agreement with the predictions. Additional experiments were performed to study the quench and thermal runaway behaviour of the HTS coils, determining whether such coils can be protected against fault scenarios, using realistic quench-detection levels and discharge extraction-rates. These experiments demonstrate that the coils are very robust and can be well protected against quenches and thermal-runaway events using common quench-protection measures with realistic parameters.</p

Optimisation of ITER Nb3Sn CICCs for coupling loss, transverse electromagnetic load and axial thermal contraction

The ITER cable-in-conduit conductors (CICCs) are built up from sub-cable bundles, wound in different stages, which are twisted to counter coupling loss caused by time-changing external magnet fields. The selection of the twist pitch lengths has major implications for the performance of the cable in the case of strain sensitive superconductors, i.e. Nb3Sn, as the electromagnetic and thermal contraction loads are large but also for the heat load from the AC coupling loss. Reduction of the transverse load and warm-up cool-down degradation can be reached by applying longer twist pitches in a particular sequence for the sub-stages, offering a large cable transverse stiffness, adequate axial flexibility and maximum allowed lateral strand support. Analysis of short sample (TF conductor) data reveals that increasing the twist pitch can lead to a gain of the effective axial compressive strain of more than 0.3 % with practically no degradation from bending. For reduction of the coupling loss, specific choices of the cabling twist sequence are needed with the aim to minimize the area of linked strands and bundles that are coupled and form loops with the applied changing magnetic field, instead of simply avoiding longer pitches. In addition we recommend increasing the wrap coverage of the CS conductor from 50 % to at least 70 %. The models predict significant improvement against strain sensitivity and substantial decrease of the AC coupling loss in Nb3Sn CICCs, but also for NbTi CICCs minimization of the coupling loss can be achieved. Although the success of long pitches to transverse load degradation was already demonstrated, the prediction of the combination with low coupling loss needs to be validated by a short sample test.Comment: to be published in Supercond Sci Techno

Measurement and Numerical Evaluation of AC Losses in a ReBCO Roebel Cable at 4.5 K

EuCARD-2 aims to research ReBCO superconducting magnets for future accelerator applications. The properties of ReBCO conductors are very different from low-temperature superconductors. To investigate dynamic field quality, stability, and normal zone propagation, an electrical network model for coated conductor cables was developed. To validate the model, two identical samples were prepared at CERN, after which measurements were taken at the University of Twente and Southampton University. The model predicts that for a Roebel cable, in a changing magnetic field applied in the perpendicular direction, hysteresis loss is much larger than coupling loss. In the case of a changing magnetic field applied parallel to the cable, coupling loss is dominant. In the first case, the experiment is in good agreement with the model. In the second case, the data can only be compared qualitatively because the calibration for the inductive measurement is not available

Research at Varian on applied superconductivity for proton therapy

Proton therapy is a rapidly increasing modality to treat cancerous tumors, but large-scale implementation, and therefore widespread availability for patients, is hindered by the size and upfront investment for treatment facilities. Superconducting technology can enable more compact, and therefore more affordable treatment systems, by increasing the magnetic field in the magnets for the proton accelerator (typically a cyclotron) and in the beam guidance up, over, and into the patient (the gantry). In this article, we discuss research at Varian Medical Systems Particle Therapy GmbH on various superconducting technologies for potential application in future, more compact cyclotrons and gantries. We discuss which technologies are feasible, and to what extent. We demonstrate why certain conductor choices are made, and show the development of novel new conductor and magnet technologies that will be required to enable the next generation of cryogen-free, conduction-cooled compact treatment systems. We conclude that superconductivity is certainly required for the next generation of proton treatment systems, but also that the amount of compactness that can eventually be achieved is not solely determined by the magnetic field strength that is generated in the magnets

AC Loss Reduction in Round HTS Cables Achieved by Low-Cost Filamentization of Tape Conductors

Knowledge of the ac loss generated in a superconducting cable during variation of magnetic field is essential when considering its use in pulsed magnets. In round high-temperature superconducting (HTS) cables made from coated conductor (CC) tapes, the hysteresis loss is proportional to the tape width. Then an effective measure for reducing the loss is the division of the superconducting layer into parallel filaments. We investigated the ac loss in short models of round cables, containing in different arrangements two layers of 10 standard helically laid tapes. At magnetic field amplitudes surpassing 0.1 T the loss did not depend on the cable architecture, in agreement with simple analytical prediction. Substantial reduction of magnetization loss was obtained in the cable models from novel coated conductor (CC) tapes with a low-cost filamentized REBCO layer produced in an industrial process utilizing a special 3D patterned metal substrate. Further research should address the improvement of critical current and optimization of metallic layers, allowing a migration of current between filaments without substantial increase of coupling loss.</p

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

Dendritic cells are the professional antigen-presenting cells of the immune system. To induce an effective immune response, these cells should not only express high levels of MHC and costimulatory molecules but also migrate into the lymph nodes to interact with naïve T cells. Here, we demonstrate that in vitro-generated mature, but not immature dendritic cells, efficiently migrate into the T-cell areas of lymph nodes of melanoma patients. This difference is confirmed by in vitro studies, in which immature dendritic cells are strongly adherent, whereas mature dendritic cells remain highly motile. Our present findings demonstrate that the ability of dendritic cells to mount a proper immune response correlates with their ability to migrate both in vitro and in viv