142 research outputs found
Odrzucenie czy akceptacja? Hollywood w Holandii
Publikacja została sfinansowana ze środków Narodowego Programu Rozwoju Humanistyki w ramach projektu nr 12H 11 0004 8
Prison area, independence valley: American paradoxes in political life and popular culture
Rob Kroes is professor emeritus of American studies at the University of Amsterdam, now also honorary professor at the University of Utrecht. One of Europe\u27s leading American studies scholars, he is the author of numerous books and articles, including Photographic Memories: Private Pictures, Public Images, and American History.
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Hans Bak, Frank Mehring, Mathilde Roza, eds., Politics and Cultures of Liberation: Media, Memory, and Projections of Democracy
Hans Bak, Frank Mehring, Mathilde Roza, eds., Politics and Cultures of Liberation: Media, Memory, and Projections of Democracy Leiden/Boston: Brill, 2018. Pp. 368. ISBN: 9789004292017 Rob Kroes This volume of essays is written from many angles, and shifts focus from narrower to wider ones. Yet, consistently, it centers on exploring the local in histories more commonly set in national or global frames. Trans-nationalism may be all the rage in recent turns that American Studies has taken, here..
American Studies in Europe or : Brother, can you paradigm ?
Il s'agit du texte d'une communication prononcée en ouverture des Doctoriales de l'AFEA à Orléans le 24 mai 2001. Il comporte deux parties, l'une proposant une définition du paradigme des études américaines dans une perspective internationale, l'autre à travers des études d'images publicitaires essayant de montrer comment la culture de masse américaine influe sur les cultures européennes
Clinical characterization of 66 patients with congenital retinal disease due to the deep-intronic c.2991+1655A>G mutation in CEP290
Purpose: To describe the phenotypic spectrum of retinal disease caused by the c.2991+1655A>G mutation in CEP290 and to compare disease severity between homozygous and compound heterozygous patients.
Methods: Medical records were reviewed for best-corrected visual acuity (BCVA), age of onset, fundoscopy descriptions. Foveal outer nuclear layer (ONL) and ellipsoid zone (EZ) presence was assessed using spectral-domain optical coherence tomography (SD-OCT). Differences between compound heterozygous and homozygous patients were analyzed based on visual performance and visual development.
Results: A total of 66 patients were included. The majority of patients had either light perception or no light perception. In the remaining group of 14 patients, median BCVA was 20/195 Snellen (0.99 LogMAR; range 0.12-1.90) for the right eye, and 20/148 Snellen (0.87 LogMAR; range 0.22-1.90) for the left. Homozygous patients tended to be more likely to develop light perception compared to more severely affected compound heterozygous patients (P = 0.080) and are more likely to improve from no light perception to light perception (P = 0.022) before the age of 6 years. OCT data were available in 12 patients, 11 of whom had retained foveal ONL and EZ integrity up to 48 years (median 23 years) of age.
Conclusions: Homozygous patients seem less severely affected compared to their compound-heterozygous peers. Improvement of visual function may occur in the early years of life, suggesting a time window for therapeutic intervention up to the approximate age of 17 years. This period may be extended by an intact foveal ONL and EZ on OCT
Editors’ Introduction
A new birth of freedom. These words spoken by Abraham Lincoln on a Civil War battlefield catch what this volume intends to explore. Repeatedly wars have been seen as offering new beginnings, requiring a new start, promising rejuvenation. At the time of World War I Randolph Bourne advocated American non-intervention, seeing it as America’s chance to cut the umbilical cord with the English mother culture, as a chance for America finally to come into its own as a “transnational culture.” If war ..
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