Interoperability Challenges in the Cybersecurity Information Sharing Ecosystem

Threat intelligence helps businesses and organisations make the right decisions in their fight against cyber threats, and strategically design their digital defences for an optimised and up-to-date security situation. Combined with advanced security analysis, threat intelligence helps reduce the time between the detection of an attack and its containment. This is achieved by continuously providing information, accompanied by data, on existing and emerging cyber threats and vulnerabilities affecting corporate networks. This paper addresses challenges that organisations are bound to face when they decide to invest in effective and interoperable cybersecurity information sharing and categorises them in a layered model. Based on this, it provides an evaluation of existing sources that share cybersecurity information. The aim of this research is to help organisations improve their cyber threat information exchange capabilities, to enhance their security posture and be more prepared against emerging threats

Disruption of the pollen-expressed FERONIA homologs ANXUR1 and ANXUR2 triggers pollen tube discharge

The precise delivery of male to female gametes during reproduction in eukaryotes requires complex signal exchanges and a flawless communication between male and female tissues. In angiosperms, molecular mechanisms have recently been revealed that are crucial for the dialog between male (pollen tube) and female gametophytes required for successful sperm delivery. When pollen tubes reach the female gametophyte, they arrest growth, burst and discharge their sperm cells. These processes are under the control of the female gametophyte via the receptor-like serine-threonine kinase (RLK) FERONIA (FER). However, the male signaling components that control the sperm delivery remain elusive. Here, we show that ANXUR1 and ANXUR2 (ANX1, ANX2), which encode the closest homologs of the FER-RLK in Arabidopsis, are preferentially expressed in pollen. Moreover, ANX1-YFP and ANX2-YFP fusion proteins display polar localization to the plasma membrane at the tip of the pollen tube. Finally, genetic analyses demonstrate that ANX1 and ANX2 function redundantly to control the timing of pollen tube discharge as anx1 anx2 double-mutant pollen tubes cease their growth and burst in vitro and fail to reach the female gametophytes in vivo. We propose that ANX-RLKs constitutively inhibit pollen tube rupture and sperm discharge at the tip of growing pollen tubes to sustain their growth within maternal tissues until they reach the female gametophytes. Upon arrival, the female FER-dependent signaling cascade is activated to mediate pollen tube reception and fertilization, while male ANX-dependent signaling is deactivated, enabling the pollen tube to rupture and deliver its sperm cells to effect fertilization