70 research outputs found
Untersuchung der Vasotocin- und Galanin-Expression nach osmotischer Stimulation im HĂŒhnergehirn
[no abstract
Capitale In Pedilavio Balneum Pro Septem Capitalibus Vitiis, in totidem Sanguinis Theandrici Effusionibus Ă Christo Patiente instructum
Parallel Quantum-Point-Contacts as High-Frequency-Mixers
We present the results of high-frequency mixing experiments performed upon
parallel quantum point-contacts defined in the two-dimensional electron gas of
an Al_{x}Ga_{1-x}As/GaAs-heterostructure. The parallel geometry, fabricated
using a novel double-resist technology, enables the point-contact device to be
impedance matched over a wide frequency range and, in addition, increases the
power levels of the mixing signal while simultaneously reducing the parasitic
source-drain capacitance. Here, we consider two parallel quantum point-contact
devices with 155 and 110 point-contacts respectively; both devices operated
successfully at liquid helium and liquid nitrogen temperatures with a minimal
conversion loss of 13 dB.Comment: 4 figures, RevTeX, to be published in the 16 June 1997 issue of
Applied Physic Letter
Treatment of Bone Marrow Edema of the Foot and Ankle With the Prostacyclin Analog Iloprost
Background: Bone marrow edema (BME) of the foot and ankle is challenging to treat. One approach is intravenous Iloprost treatment, which is a vasoactive prostacyclin analog. The aim of this study was to evaluate the early and intermediate outcome of intravenous Iloprost therapy on BME of the foot and ankle and to analyze the influence of its etiology and Association Research Circulation Osseous (ARCO) stage on the outcome. Methods: This was a retrospective study with prospective follow-up. All patients treated by intravenous Iloprost for BME of the foot and ankle (ARCO I-III) at a single orthopedic reference center were included. Demographics, medical history, and MRIs were assessed prior to treatment (t0). MRIs were used to assess the BMEs' etiology (idiopathic/ ischemic/ metabolic, mechanical/ degenerative, traumatic) and severity (ARCO). Complications as well as changes in pain, treatment, and MRI were evaluated after 3 months (t1). The following patient-rated outcome measures (PROMs) were assessed prospectively (t2): 12Item Short Form Health Survey (SF-12), Visual Analog Scale Foot and Ankle (VAS FA), and the Foot Function Index (FFI) (also at t0). The descriptive outcomes and the influence of the etiology and ARCO on the outcome parameters were evaluated. Out of 70 eligible patients, 42 patients (60%;47 +/- 15 years;30% female) with a mean follow-up of 28 +/- 19 months were included. Results: Twelve patients reported minor complications during Iloprost therapy. At t1, pain decreased significantly in 56%, and the amount of BME decreased in 83% of patients. Both parameters correlated moderately (r = -0.463, P =.015). The PROMs at t2 revealed moderate results. The overall FFI improved from 59 +/- 21 to 30 +/- 22 (P <.001), the overall VAS FA was 68 +/- 20, the SF-12 Physical Component Summary 42 +/- 12 and Mental Component Summary 50 +/- 9. Subgroup analysis revealed no significant influence of the etiology or ARCO stage on any outcome measure. Conclusion: Iloprost therapy for BME of the foot and ankle resulted in a 60% pain and 80% edema decrease after 3 months. After 2 years, patient-rated outcome measures showed residual impairment. Neither the etiology nor ARCO stage significantly influenced the outcome
Functional Medium-Term Results After Autologous Matrix-Induced Chondrogenesis for Osteochondral Lesions of the Talus: A 5-Year Prospective Cohort Study
Autologous matrix-induced chondrogenesis (AMIC) has gained popularity in the treatment of osteochondral lesions of the talus. Previous studies have presented promising short-term results for AMIC talar osteochondral lesion repair, a 1-step technique using a collagen type I/III bilayer matrix. The aim of the present study was to investigate the mid-term effects. The 5-year results of a prospective cohort study are presented. All patients underwent an open AMIC procedure for a talar osteochondral lesion. Data analysis included general demographic data, preoperative magnetic resonance imaging findings, intraoperative details, and German version of the Foot Function Index (FFI-D) scores preoperatively and at 1 and 5 years after surgery. The primary outcome variable was the longitudinal effect of the procedure, and the influence of various variables on the outcome was tested. Of 47 consecutive patients, 21 (45%) were included. Of the 21 patients, 8 were female (38%) and 13 were male (62%), with a mean age of 37 +/- 15 (range 15 to 62) years and a body mass index of 26 +/- 5 (range 20 to 38) kg/m(2). The defect size was 1.4 0.9 (range 0.2 to 4.0) cm(2). The FFI-D decreased significantly from preoperatively to 1 year postoperatively (56 +/- 18 versus 33 +/- 25;p =.003), with a further, nonsignificant decrease between the 1- and 5-year follow-up examination (33 +/- 25 versus 24 +/- 21;p = .457). Similar results were found for the FFI-D subscales of function and pain. The body mass index and lesion size showed a positive correlation with the preoperative FFI-D overall and subscale scores. These results showed a significant improvement in pain and function after the AMIC procedure, with a significant return to sports by the 5-year follow-up point. The greatest improvement overall was seen within the first year;however, further clinical satisfaction among the patients was noticeable after 5 years. (C) 2017 by the American College of Foot and Ankle Surgeons
Rekonstruktion umschriebener Knorpeldefekte des Talus mittels Miniarthrotomie und Kollagenmatrix
Die Entwicklung des mĂ€nnlichen Genitaltrakts und testikulĂ€rer Funktionen in AbhĂ€ngigkeit vom SchilddrĂŒsenhormonspiegel der Maus
Skolkuratorn i arbete : "Man gör vÀl det bÀsta man kan efter de förutsÀttningar man har"
Abstract Sverige ligger i topp bland EU-lÀnderna nÀr det gÀller ungdomar med psykosomatiska besvÀr. Detta medför frÄgan om vilka stödinsatser som finns tillgÀngliga för eleverna i den svenska skolan, samt hur skolkuratorerna arbetar med frÄgor som psykisk ohÀlsa och stressrelaterade problem. Skolkuratorns fokus Àr instÀllt pÄ ett socialt arbete med individ, grupp och organisation, och förutsÀttningarna för skolkuratorns arbetsuppgifter Àr beroende av skollagen, som reglerar skolans verksamhet. Syftet med denna studie Àr att söka kunskap och förstÄelse för hur skolkuratorer arbetar med högstadieelevers psykiska hÀlsa i skolorganisationen. Vi har Àven som mÄlsÀttning att finna lösningsförslag pÄ den problematik som studien finner inom det specificerade omrÄdet. I den nya skollagen, som börjar gÀlla frÄn och med 1 juli, 2011, stÄr det att det ska finnas "tillgÄng" till en elevhÀlsa för eleverna, vilket Àven innefattar bland annat skolkuratorer. Innebörden i ordet tillgÄng Àr dÀremot inte specificerat. Studien visar att det kan uppstÄ krockar mellan skolkuratorn och lÀrare dÄ spelplanen inom skolan Àr pedagogernas arena. Detta kan ofta betyda att det Àr deras synsÀtt som Àr rÄdande i vad som Àr de bÀsta ÄtgÀrderna för eleven. Problemlösningsprocessen i skolkuratorns arbete pekar pÄ att samverkan mellan socialtjÀnsten Àr problematisk. Det handlar ofta om svÄrigheter kring att bestÀmma möten, att veta vem eller vilka som Àr inkopplade i Àrenden som rör elever. De tematiserade omrÄden dÀr vi fokuserat vÄr studie Àr arbetsmetoder, organisation och samverkan. Vi anvÀnder oss av en kvalitativ metod dÄ vi intervjuat fem skolkuratorer i Stockholm. Bearbetning och analys har skett enligt organisationsteori och vi har tolkat samspel mellan individer och grupper utifrÄn i första hand rollteorin. Studien har kommit fram till att skolkuratorernas arbete i mÄnga sammanhang Àr understÀlld skolorganisationens styre och att de sjÀlva mÄste utveckla och definiera sitt uppdrag utifrÄn detta. Denna studie har funnit att skolkuratorns otydliga organisatoriska position och stÀllning bör omorganiseras och tydliggöras. Skola och kommun bör ta ett större ansvar i att definiera skolkuratorns formella uppdrag och praktiska arbetsuppgifter. Studien avslutas med lösningsförslag och ÄtgÀrder som kan öka förutsÀttningarna för att barn och unga som har behov av det behov fÄr del av det stöd som lagen sÀger att de har rÀtt till.
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