918 research outputs found
Feasibility of self-structured current accessed bubble devices in spacecraft recording systems
The self-structured, current aperture approach to magnetic bubble memory is described. Key results include: (1) demonstration that self-structured bubbles (a lattice of strongly interacting bubbles) will slip by one another in a storage loop at spacings of 2.5 bubble diameters, (2) the ability of self-structured bubbles to move past international fabrication defects (missing apertures) in the propagation conductors (defeat tolerance), and (3) moving bubbles at mobility limited speeds. Milled barriers in the epitaxial garnet are discussed for containment of the bubble lattice. Experimental work on input/output tracks, storage loops, gates, generators, and magneto-resistive detectors for a prototype device are discussed. Potential final device architectures are described with modeling of power consumption, data rates, and access times. Appendices compare the self-structured bubble memory from the device and system perspectives with other non-volatile memory technologies
TaLoS: secure and transparent TLS termination inside SGX enclaves
We introduce TaLoS1, a drop-in replacement for existing transport layer security (TLS) libraries that protects itself from a malicious environment by running inside an Intel SGX trusted execution environment. By minimising the amount of enclave transitions and reducing the overhead of the remaining enclave transitions, TaLoS imposes an overhead of no more than 31% in our evaluation with the Apache web server and the Squid proxy
Analyticity and criticality results for the eigenvalues of the biharmonic operator
We consider the eigenvalues of the biharmonic operator subject to several
homogeneous boundary conditions (Dirichlet, Neumann, Navier, Steklov). We show
that simple eigenvalues and elementary symmetric functions of multiple
eigenvalues are real analytic, and provide Hadamard-type formulas for the
corresponding shape derivatives. After recalling the known results in shape
optimization, we prove that balls are always critical domains under volume
constraint.Comment: To appear on the proceedings of the conference "Geometric Properties
for Parabolic and Elliptic PDE's - 4th Italian-Japanese Workshop" held in
Palinuro (Italy), May 25-29, 201
Classical versus quantum dynamics of the atomic Josephson junction
We compare the classical (mean-field) dynamics with the quantum dynamics of
atomic Bose-Einstein condensates in double-well potentials. The quantum
dynamics are computed using a simple scheme based upon the Raman-Nath
equations. Two different methods for exciting a non-equilbrium state are
considered: an asymmetry between the wells which is suddenly removed, and a
periodic time oscillating asymmetry. The first method generates wave packets
that lead to collapses and revivals of the expectation values of the
macroscopic variables, and we calculate the time scale for these revivals. The
second method permits the excitation of a single energy eigenstate of the
many-particle system, including Schroedinger cat states. We also discuss a band
theory interpretation of the energy level structure of an asymmetric
double-well, thereby identifying analogies to Bloch oscillations and Bragg
resonances. Both the Bloch and Bragg dynamics are purely quantum and are not
contained in the mean-field treatment.Comment: 31 pages, 14 figure
Lieb-Thirring inequalities for geometrically induced bound states
We prove new inequalities of the Lieb-Thirring type on the eigenvalues of
Schr\"odinger operators in wave guides with local perturbations. The estimates
are optimal in the weak-coupling case. To illustrate their applications, we
consider, in particular, a straight strip and a straight circular tube with
either mixed boundary conditions or boundary deformations.Comment: LaTeX2e, 14 page
Progression to chronic atrial fibrillation after pacing: the Canadian Trial of Physiologic Pacing
AbstractOBJECTIVESThis study examined the effect of physiologic pacing on the development of chronic atrial fibrillation (CAF) in the Canadian Trial Of Physiologic Pacing (CTOPP).BACKGROUNDThe role of physiologic pacing to prevent CAF remains unclear. Small randomized studies have suggested a benefit for patients with sick sinus syndrome. No data from a large randomized trial are available.METHODSThe CTOPP randomized patients undergoing first pacemaker implant to ventricular-based or physiologic pacing (AAI or DDD). Patients who were prospectively found to have persistent atrial fibrillation (AF) lasting greater than or equal to one week were defined as having CAF. Kaplan-Meier plots for the development of CAF were compared by log-rank test. The effect of baseline variables on the benefit of physiologic pacing was evaluated by Cox proportional hazards modeling.RESULTSPhysiologic pacing reduced the development of CAF by 27.1%, from 3.84% per year to 2.8% per year (p = 0.016). Three clinical factors predicted the development of CAF: age ≥74 years (p = 0.057), sinoatrial (SA) node disease (p < 0.001) and prior AF (p < 0.001). Subgroup analysis demonstrated a trend for patients with no history of myocardial infarction or coronary disease (p = 0.09) as well as apparently normal left ventricular function (p = 0.11) to derive greatest benefit.CONCLUSIONSPhysiologic pacing reduces the annual rate of development of chronic AF in patients undergoing first pacemaker implant. Age ≥74 years, SA node disease and prior AF predicted the development of CAF. Patients with structurally normal hearts appear to derive greatest benefits
Risk Factors for CIED Infection After Secondary Procedures
OBJECTIVES This study aimed to identify risk factors for infection after secondary cardiac implantable electronic device (CIED) procedures. BACKGROUND Risk factors for CIED infection are not well defined and techniques to minimize infection lack supportive evidence. WRAP-IT (World-wide Randomized Antibiotic Envelope Infection Prevention trial), a large study that assessed the safety and efficacy of an antibacterial envelope for CIED infection reduction, offers insight into procedural details and infection prevention strategies. METHODS This analysis included 2,803 control patients from the WRAP-IT trial who received standard preoperative antibiotics but not the envelope (44 patients with major infections through all follow-up). A multivariate least absolute shrinkage and selection operator machine learning model, controlling for patient characteristics and procedural variables, was used for risk factor selection and identification. Risk factors consistently retaining predictive value in the model (appeared >10 times) across 100 iterations of imputed data were deemed significant. RESULTS Of the 81 variables screened, 17 were identified as risk factors with 6 being patient/device-related (nonmodifiable) and 11 begin procedure-related (potentially modifiable). Patient/device-related factors included higher number of previous CIED procedures, history of atrial arrhythmia, geography (outside North America and Europe), device type, and lower body mass index. Procedural factors associated with increased risk included longer procedure time, implant location (non-left pectoral subcutaneous), perioperative glycopeptide antibiotic versus nonglycopeptide, anticoagulant, and/or antiplatelet use, and capsulectomy. Factors associated with decreased risk of infection included chlorhexidine skin preparation and antibiotic pocket wash. CONCLUSIONS In WRAP-IT patients, we observed that several procedural risk factors correlated with infection risk. These results can help guide infection prevention strategies to minimize infections associated with secondary CIED procedures. (J Am Coll Cardiol EP 2022;8:101-111) (c) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
PCV23 REDUCTIONS IN CORONARY HEART DISEASE MORTALITY ASSOCIATED WITH CHANGES IN RISK FACTORS AND TREATMENT UPTAKES IN ONTARIO BETWEEN 1994 AND 2005
Neutrino and Antineutrino Inclusive Charged-current Cross Section Measurements with the MINOS Near Detector
The energy dependence of the neutrino-iron and antineutrino-iron inclusive
charged-current cross sections and their ratio have been measured using a
high-statistics sample with the MINOS Near Detector exposed to the NuMI beam
from the Main Injector at Fermilab. Neutrino and antineutrino fluxes were
determined using a low hadronic energy subsample of charged-current events. We
report measurements of neutrino-Fe (antineutrinoFe) cross section in the energy
range 3-50 GeV (5-50 GeV) with precision of 2-8% (3-9%) and their ratio which
is measured with precision 2-8%. The data set spans the region from low energy,
where accurate measurements are sparse, up to the high-energy scaling region
where the cross section is well understood.Comment: accepted by PR
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Measurement of the underground atmospheric muon charge ratio using the MINOS Near Detector
The magnetized MINOS Near Detector, at a depth of 225 mwe, is used to measure the atmospheric muon charge ratio. The ratio of observed positive to negative atmospheric muon rates, using 301 days of data, is measured to be 1.266±0.001(stat)_(-0.014)^(+0.015)(syst). This measurement is consistent with previous results from other shallow underground detectors and is 0.108±0.019(stat+syst) lower than the measurement at the functionally identical MINOS Far Detector at a depth of 2070 mwe. This increase in charge ratio as a function of depth is consistent with an increase in the fraction of muons arising from kaon decay for increasing muon surface energie
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