7,461 research outputs found
Rhapsody in Red, White and Blue: The Co-Evolution of Popular and Art Music in the United States during World War II
World War II was a watershed event in twentieth century American history. All aspects of life, including music, both found roles to play in the war effort and were forever altered by the conflict. Past work on the subject of American music in World War II tends to focus heavily on the nature and impact of popular music during this time period. While this paper will review and build upon this scholarship, art music during the war will also be considered. Using two distinctly different, yet complementary, autobiographies – those of army band musician Frank Mathias and composer Gunther Schuller – the functions and impacts of both popular and art music on the American war effort will be analyzed and compared. Their stories will then be contextualized within the larger narrative of twentieth century American music, showcasing how World War II – through the increased influence of jazz – shaped the evolution of both popular and art music in the United States during the early 1940s
European Jazz: A Comparative Investigation into the Reception and Impact of Jazz in Interwar Paris and the Weimar Republic
Both Paris and the Weimar Republic were fascinated with American jazz in the interwar period. Because of jazz\u27s connection to African American culture, this fascination is linked with the themes of identity and race relations. This work will demonstrate that interwar Parisians were not always receptive of African Americans that played jazz, and that the citizens of the Weimar Republic were more aware of and interested in the African American culture that permeated jazz in the 1920s and 30s
Effects of Orthogonal Rotating Electric Fields on Electrospinning Process
Electrospinning is a nanotechnology process whereby an external electric
field is used to accelerate and stretch a charged polymer jet, so as to produce
fibers with nanoscale diameters. In quest of a further reduction in the cross
section of electrified jets hence of a better control on the morphology of the
resulting electrospun fibers, we explore the effects of an external rotating
electric field orthogonal to the jet direction. Through extensive particle
simulations, it is shown that by a proper tuning of the electric field
amplitude and frequency, a reduction of up to a in the aforementioned
radius can be obtained, thereby opening new perspectives in the design of
future ultra-thin electrospun fibres. Applications can be envisaged in the
fields of nanophotonic components as well as for designing new and improved
filtration materials.Comment: 22 pages, 8 figure
Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis
Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessary for oncogenesis. One key feature of oncogenic transformation is dysregulation of cell cycle control. It is therefore likely that EWS/FLI and other cooperating mutations in Ewing's sarcoma modulate the cell cycle to facilitate tumorigenesis. This paper will summarize current published data associated with deregulation of the cell cycle in Ewing's sarcoma and highlight important questions that remain to be answered
Dean flow-coupled inertial focusing in curved channels
Passive particle focusing based on inertial microfluidics was recently introduced as a high-throughput alternative to active focusing methods that require an external force field to manipulate particles. In inertial microfluidics, dominant inertial forces cause particles to move across streamlines and occupy equilibrium positions along the faces of walls in flows through straight micro channels. In this study, we systematically analyzed the addition of secondary Dean forces by introducing curvature and show how randomly distributed particles entering a simple u-shaped curved channel are focused to a fixed lateral position exiting the curvature. We found the lateral particle focusing position to be fixed and largely independent of radius of curvature and whether particles entering the curvature are pre-focused (at equilibrium) or randomly distributed. Unlike focusing in straight channels, where focusing typically is limited to channel cross-sections in the range of particle size to create single focusing point, we report here particle focusing in a large cross-section area (channel aspect ratio 1: 10). Furthermore, we describe a simple u-shaped curved channel, with single inlet and four outlets, for filtration applications. We demonstrate continuous focusing and filtration of 10 mu m particles (with > 90% filtration efficiency) from a suspension mixture at throughputs several orders of magnitude higher than flow through straight channels (volume flow rate of 4.25ml/min). Finally, as an example of high throughput cell processing application, white blood cells were continuously processed with a filtration efficiency of 78% with maintained high viability. We expect the study will aid in the fundamental understanding of flow through curved channels and open the door for the development of a whole set of bio-analytical applications
Power cycling analysis of enameled aluminium winding wires connections pprepared with the use of SHARK-Al® type connectors
The article presents the research results of current cyclic thermal tests performed on enamelled aluminium wires connections, made with the use of a new type of Shark-Al quick-connectors. In particular, the main purpose of the conducted research was to analyse the effect of cyclic heating on the contact resistance change during the tests which allows to test the stability of the connections in simulated working conditions under current flow. Tests included a total of 300 thermal cycles, of which the first 200 were carried out to the 65 °C temperature measured in the connector at above the ambient temperature, and then additional 100 cycles were performed for the temperature of the connector at 140 °C (tolerance +5 °C). During the tests, the resistance of samples was monitored, which allowed to verify the correctness of performed connections
Influence of surgical resection no plasma Endoglin (CD105) level in non-small cell lung cancer patients
Background and Aim: Endoglin is a proliferation-associated antigen on endothelial cells and essential for angiogenesis. Soluble endoglin (s‑endoglin), formed by proteolytic cleavage of ectodomain of membrane receptor could be an indicator of tumor‑activated endothelium. The aim of present study was to analyze changes of s‑endoglin level in plasma of lung cancer patients following surgical resection and to estimate the correlation of s‑endoglin with other soluble receptors, sTie2 and sVEGF R1. Patients and Methods: The study group consisted of 37 patients with stage I of non-small cell lung cancer. Plasma concentrations of s‑endoglin, sTie2 and sVEGF R1 were evaluated by ELISA, three times: before surgical resection and on postoperative day 7 and 30. Results: The median of s‑endoglin concentration decreased significantly on postoperative day 7 when compared with preoperative level and next increased on 30th day and it was comparable with that before surgery. s-Endoglin correlated with another soluble receptors, with sTie2 both before surgery (r=0.44) and on postoperative day 7 (r=0.52) and on 30th day (r=0.58), with sVEGF R1 — only on postoperative day 7 (r=0.75). Conclusion: The increased level of serum endoglin in lung cancer patients compared to controls and its changes after surgical treatment suggest potential application of soluble form of endoglin as potential tumor marker
Variation in Seagrass-Associated Macroinvertebrate Communities Along the Gulf Coast of Peninsular Florida: An Exploration of Patterns and Ecological Consequences
Seagrasses form vast meadows of structurally complex habitat that support faunal communities with greater numbers of species and individuals than nearby unstructured habitats. The Gulf coast of peninsular Florida represents a natural laboratory ideally suited to the study of processes that shape seagrass-associated invertebrate and fish communities within meadows of a single species of seagrass, Thalassia testudinum. This suitability arises from a pronounced structural and chemical gradient that exists over ecologically relevant spatial and temporal scales, as revealed by extensive monitoring of water quality and seagrass. We hypothesized that seagrass-associated invertebrate communities would vary across five estuarine systems spread along a spatial gradient in phosphorus concentration, an important driver of seagrass and phytoplankton growth in this region. The quantitative results based on data acquired at 25 stations (75 samples, 52,086 specimens, and 161 taxa) indicated that each of the five estuarine systems were distinct with regard to species composition and differences among systems were driven by abundant or relatively common species. In addition, we found evidence to indicate food webs in seagrass meadows along this gradient may differ, especially in the relative dominance of algal grazers and predatory invertebrates. These changes in species composition and trophic roles could be driven by phosphorus directly, through increases in rates of primary production with higher concentrations of phosphorus, or indirectly, through nutrient-mediated changes in the physical structure of the seagrass canopy. Our results suggest that differences in the habitat created by T. testudinum under differing phosphorus supplies lead to ecologically significant shifts in macroinvertebrate communities
A World Full of Privacy and Security (Mis)conceptions? Findings of a Representative Survey in 12 Countries
Misconceptions about digital security and privacy topics in the general public frequently lead to insecure behavior. However, little is known about the prevalence and extent of such misconceptions in a global context. In this work, we present the results of the first large-scale survey of a global population on misconceptions: We conducted an online survey with n = 12, 351 participants in 12 countries on four continents. By investigating influencing factors of misconceptions around eight common security and privacy topics (including E2EE, Wi-Fi, VPN, and malware), we find the country of residence to be the strongest estimate for holding misconceptions. We also identify differences between non-Western and Western countries, demonstrating the need for region-specific research on user security knowledge, perceptions, and behavior. While we did not observe many outright misconceptions, we did identify a lack of understanding and uncertainty about several fundamental privacy and security topics
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