Generalization of perturbed trapezoid formula and related inequalities

We derive some new inequalities for perturbed trapezoid formula and give some sharp and best possible constants

IMPACT OF GLOBAL WARMING ON AVERAGE ANNUAL AIR TEMPERATURE IN VARAŽDIN

Climate change implies a statistically significant change in the long-term mean state or characteristics of the variability of climate elements. It can be caused by natural and/or anthropogenic factors. Recent global warming is often cited as an example of human-induced climate change. Global warming refers to the increasing trend of the average global surface temperature of the Earth, defined as the global average of the mean annual surface temperature of the ocean, usually to a depth of 30-100 cm, and the mean annual surface temperature of the air above the land at a height of 1-2 m above the ground. In 1988, the World Meteorological Organization (WMO) and the United Nations Environment Program (UNEP) established the International Panel on Climate Change (IPCC), which assesses the state of the climate and the risk of climate change caused by human activities.To project climate change, it is necessary to determine the future emissions of greenhouse gases in the atmosphere. According to the IPCC, with appropriate scenarios of greenhouse gas emissions, an increase in the average global surface temperature of 1.5 °C to 4 °C is predicted by the end of the 21st century. The purpose of this paper is to show the relationship between the trend and variability of the global average of the mean annual surface temperature on Earth and the trend of the mean annual air surface temperature in Varaždin for the period 1949-2021. The results show significant correlations among them because Varaždin is located in an big area of surface air temperature anomalies which has a significant contribution to a global average anomalies in several last decades

Klinički i elektrofiziološki znaci dijabetične polineuropatije – utjecaj glikemije i trajanja šećerne bolesti

Diabetic polyneuropathy occurs in around 50% of diabetic patients. Its pathophysiological mechanism is not completely clarified and major occurrences boil down to the change in neural phenotype and vasa nervorum. As glucose neurotoxicity has been suggested by plenty of evidence, the aim of the study was to assess the effect of glycemia on the severity of diabetic polyneuropathy. Considering that some practical experiences point to serious complications in patients suffering from diabetes of shorter duration, another aim was to assess the effect of diabetes duration on the severity of related neuropathy. Clinical and electromyoneurographic examinations were performed in 100 patients with diabetic polyneuropathy free from any laboratory signs of renal failure. The effect of HbA1c value and duration of disease on clinical symptoms, signs and electrophysiological indicators of polyneuropathy was analyzed. Study results indicated that 78% of patients with diabetic polyneuropathy did not have well-regulated glycemia. Diabetes duration was associated with a growing number of sensory symptoms, among which the sensation of pain similar to electric shock was present in 63% of patients. In addition, it also had negative impact on the sensory and motor nerve conduction velocity. HbA1c influenced the whole range of electrophysiological indicators of diabetic polyneuropathy.Dijabetična polineuropatija javlja se u oko 50% bolesnika s dijabetesom. Njezin patofiziološki mehanizam nastanka nije u potpunosti razjašnjen, a glavna zbivanja svode se na promjenu neuralnog fenotipa i vasa nervorum. Kako postoje mnogi dokazi o neurotoksičnosti glukoze, cilj studije bio je ispitati utjecaj glikemije na težinu dijabetične polineuropatije. Budući da neka iskustva u praksi upućuju na prisutnost teških komplikacija u bolesnika koji imaju dijabetes kraćeg trajanja, ispitao se utjecaj dužine trajanja dijabetesa na težinu pridružene neuropatije. Klinički i elektromioneurografski je ispitano 100 bolesnika s dijabetičnom polineuropatijom. Uvjet je bio da bolesnici nemaju laboratorijske znakove bubrežnog oštećenja, a analizirao se utjecaj vrijednosti HbA1c i trajanja bolesti na kliničke simptome, znakove i elektrofiziološke pokazatelje polineuropatije. Rezultati su pokazali da 78% bolesnika s dijabetičnom polineuropatijom nema dobro reguliranu glikemiju. Trajanje dijabetesa utječe na pojavu većeg broja senzornih simptoma, od kojih se osjećaj boli poput udara struje javlja u 63% bolesnika, a utječe i na pogoršanje brzine provodljivosti senzornih i motornih živaca. HbA1c utječe na čitav niz elektrofizioloških pokazatelja dijabetične polineuropatije

Generalization of perturbed trapezoid formula and related inequalities

We derive some new inequalities for perturbed trapezoid formula and give some sharp and best possible constants

DEPENDENCE OF CONCENTRATION OF RADON ON ENVIRONMENTAL PARAMETERS – MULTIPLE LINEAR REGRESSION MODEL

Radon (222Ra) is a colourless and odourless natural radioactive element in gaseous state. The concentration of radon in the air is usually low, but it can be very high inside of a living space, because of its possibility to penetrate from a foundation soil over a basement into a building itself. People are daily exposed to a certain concentration of radon that is found in soil, water, air and food. This paper shows a correlation analysis of environmental parameters by using the model of multiple regressions. It defines certain statistical relations between environmental parameters such as temperature, humidity, and atmospheric pressure with measured values of radon concentrations. Measurements were carried out at several locations in various residential buildings in north-western Croatia. The results indicated that individual environmental parameters and radon concentration at individual locations were connected. For example, at one location the concentration of radon was decreasing if atmospheric pressure was increasing. Measurements at another location indicated that the concentration of radon was increasing if air humidity was increasing. Due to large number of different parameters affecting the concentration of radon in residential buildings, a satisfactory statistical model to predict the concentration of radon with environmental parameters is not easy to achieve since it was observed variability of radon concentrations with environmental parameters within different local sites. It is necessary to consider a longer period to determine with certainty a mathematical model that would give the most accurate prediction of radon concentration dependence on environmental parameters which can affect human health and quality of life

Domestic Homicide Cases Related to Schizophrenic Offenders

The goal of this study was identification of highly specific patterns of schizophrenia related domestic homicides by comparing schizophrenic homicide offenders with related domestic homicide group of offenders diagnosed with other psychiatric disorders. This study was based on the comparison of schizophrenic homicide group and other homicide group of offenders on the basis of differences in psychosocial and sociodemographic patterns and the modality of crime. The survey was conducted on mentally insane domestic homicide offenders diagnosed with schizophrenia (n=44) and second group of mentally insane offenders diagnosed with other psychiatric diagnosis (n=43). All offenders were admitted to Department of Forensic Psychiatry (Neuropsychiatric Hospital »Dr. Ivan Barbot«, Popovaca, Croatia) for psychiatric evaluation. They have undergone psychological testing and psychiatric evaluation in order to make forensic expert analyses of each case particularly. This study showed some specific characteristics in the cases of schizophrenic offenders; they are more often commit parricides and siblicides, the victims are often males with their own physical strength. Furthermore, schizophrenic offenders were indifferent upon killing their victim; they were less often provoked by a victim itself and were sober tempore criminis. Moreover, in the same homicide group we found young, single offenders with high school education, average intelligence and with positive psychiatric heredity. Finally, in the same group of offenders we have found no history of military serving, less social developmental disruptions, less history of drug and alcohol abuse during adolescence and adult age

Correlation analysis of water quality indicators for Lake Motičnjak

U radu je provedena korelacijska analiza pojedinih pokazatelja kakvoće vode te je pomoću linearnog modela regresije i modela višestruke regresije određena statistička povezanost između fizikalno-kemijskih i mikrobioloških pokazatelja kakvoće vode za kupanje na primjeru jezera Motičnjak. Fizikalno–kemijski i mikrobiološki pokazatelji kakvoće vode određivani su na uzorcima vode tijekom kupališnih sezona na dvije lokacije jezera Motičnjak od 2010. do 2015. godine. Rezultati su pokazali na postojanje povezanosti između pojedinih fizikalno-kemijskih pokazatelja i mikrobioloških pokazatelja Escherichiae coli (EC) i crijevnih enterokoka (CE).The paper contains a correlation analysis of individual water quality indicators. A linear regression model and multiple regression model were used for determining a statistical connection between the physicochemical indicators and microbiological indicators of bathing water quality exemplified by Lake Motičnjak. The physico-chemical indicators and microbiological indicators of water quality were determined on the water samples during bathing seasons in two locations at Lake Motičnjak in the period from 2010 to 2015. The results indicated that there was a connection between individual physico-chemical indicators and microbiological indicators of Escherichia coli (E.coli) and intestinal enterococci (IE)

Uticaj DOAK i DOAC-REMOVE® na testove koagulacije u toku testiranja trombofilije kod bolesnika lečenih primenom DOAK

Background/Aim. Direct oral anticoagulants (DOACs) administration significantly interferes with coagulation as-says. The aim of the study was to evaluate the effect of DOACs and DOAC-Remove® on coagulation assays dur-ing thrombophilia testing. Methods. The study was car-ried out from January 2019 to the end of June 2020. It in-cluded 30 DOAC-treated patients, 14 females and 16 males aged 23 to 63 (median age 47.6 years), tested for thrombophilia due to venous thromboembolism (VTE). Thrombophilia testing was performed using DOAC-Remove® tablets (activated charcoal). The results before and after DOAC-Remove® were compared. Results. Posi-tive lupus anticoagulant (LA) results were observed in 20% apixaban, 100% dabigatran, and 70% rivaroxaban-treated patients, while in samples after DOAC-Remove®, the LA positivity was observed only in one from the apix-aban group. Before DOAC-Remove®, the activated pro-tein C (APC) resistance (APC-R) was measurable in 40% dabigatran and 80% rivaroxaban-treated patients, while, after using DOAC-Remove®, the APC-R was measurable in all cases. Comparing the results obtained from the sam-ples before and after DOAC-Remove®, a difference was noted in relation to all dilute Russell's viper venom time (dRVVT) coagulation tests, except for the dRVVT ratio in the apixaban group. Clot-based methods for detecting the APC resistance were significantly affected by dabigatran and less by rivaroxaban. Conclusion. DOACs were prac-tically inactivated after the addition of the DOAC-Remove®, which made it possible to perform analyses for the LA and APC-R testing freely and obtain relevant re-sults.Uvod/Cilj. Primena direktnih oralnih antikoagulansa (DOAK) značajno utiče na testove koagulacije. Cilj rada bio je da se pro- ceni uticaj DOAK i DOAC-Remove® tableta (aktivni ugalj) na testove koagulacije tokom ispitivanja trombofilije. Metode. Istraživanjem, sprovedenim od januara 2019. do juna 2020. godine, obuhvaćeno je 30 bolesnika lečenih DOAK-om i testiranih na trombofiliju zbog venskog tromboembolzma (VTE). Bilo je 14 žena i 16 muškaraca, starosti od 23 do 63 godine (medijana 47,6 godina). Ispitivanje trombofilije izvršeno je upotrebom DOAC-Remove® tableta (aktivni ugalj). Upoređivani su rezultati pre i posle primene DOAC-Remove®. Rezultati. Pozitivni rezultati za lupus antikoagulantni (LA) test dobijeni su kod 20% bolesnika lečenih apiksabanom, kod 100% bolesnika lečenih dabigatranom i kod 70% lečenih riva- roksabanom, a u uzorcima posle DOAC-Remove® pozitivnost na LA dobijena je samo kod jednog bolesnika iz grupe lečnih apiksabanom. Pre primene DOAC-Remove®, rezistencija na aktivisani protein C (activated protein C resistance – APC-R) bila je merljiva kod 40% i 80% bolesnika lečenih dabigatranom, od- nosno rivaroksabanom, dok je posle primene DOAC- Remove®, APC-R bila merljiva u svim slučajevima. Upoređivanjem rezultata dobijenih iz uzoraka pre i posle primene DOAC-Remove®, primećena je razlika u odnosu na sve testove vremena koagulacije izvršene razblaženim Russell- ovim zmijskim otrovom (dilute Russell’s viper venom time – dRVVT), osim dRVVT u grupi bolesnika lečenih apiksabanom. Na koagulacionu metodu za otkrivanje APC-R značajno je uti- cao dabigatran, a manje rivaroksaban. Zaključak. Nakon primene DOAC-Remove® tableta, DOAK su praktično inaktivisani što je omogućilo izvođenje analiza za LA i APC-R i dobijanje relevantnih rezultata testova