Carcinome adenoide kystique sous-glottique

Introduction: Laryngeal adenoid cystic carcinoma (ACC) is unusual. It accounts for 0.25% of all malignant tumors in the larynx, and only about 120 cases have been reported in the literature until now.Purpose: We report a case of subglottic ACC and examine the clinical, diagnostic, histological and therapeutic features and the outcome of this tumor in this location.Case report: A 75-year-old man, presented with a laryngeal dyspnea. The computed tomography of the larynx showed a posterior subglottic tumor. The panendoscopy revealed a large nonulcerated submucosal tumor in the posterior wall of the subglottic area. Biopsies made the diagnosis of laryngeal ACC. The patient had total laryngectomy with total thyroidectomyand bilateral lateral neck dissection. Histological examination didn't find neck metastases. The surgery was followed by a postoperative radiotherapy. There were no local recurrence or distant metastases during one year and half of follow-up.Conclusions: ACC shows a very slow growth pattern. Its diagnosis is often delayed and its treatment is based on surgery and postoperative radiotherapy. This tumor is characterized by the occurrence of local recurrence and distant metastases often several years after treatment of the primary tumor.Keywords: adenoid cystic carcinoma, subglottic, surgery, postoperative radiotherapy, survival

Efecto del extracto de cáscara de granada tunecina sobre la estabilidad oxidativa del aceite de maíz en condiciones de calentamiento

The effect of pomegranate peel extract (PPE) on the oxidative stability of corn oil during heating was studied. Oxidation was followed by determining peroxide value (PV), p-anisidine value (p-AV), free fatty acid value (FFA), conjugated dienes (CD), conjugated trienes hydroperoxides (CT) and the calculated total oxidation value (TOTOX). Polyphenol (TPC) and ortho-diphenol (TOPC) contents as well as the antioxidant activity of each oil sample were evaluated before and after heating. PPE showed a significant inhibitory effect on lipid oxidation. Heating samples for 8 hours supplemented by PPE to a level of 1000 ppm resulted in the highest significant decreases in investigated indices compared to the control and BHT values. It was concluded that the antioxidant activity of PPE delayed oxidation and can be used in the food industry to prevent and reduce lipid deterioration in oil.Se estudió el efecto del extracto de cáscara de granada (ECG) sobre la estabilidad oxidativa del aceite de maíz durante condiciones de calentamiento. La oxidación se siguió mediante la determinación del índice de peróxido (IP), el índice de p-anisidina (p-AV), el índice de acidez (IA), los dienos conjugados (DC), los hidroperóxidos de trienos conjugados (TC) y el valor calculado de la oxidación total (TOTOX). Se evaluó el contenido de polifenoles totales (PT) y de orto-difenoles (o-DF), así como la actividad antioxidante de cada muestra de aceite, antes y después del calentamiento. El ECG mostró un efecto inhibidor significativo sobre la oxidación de lípidos. El calentamiento de las muestras, durante 8 horas suplementadas con ECG a un nivel de 1000 ppm, dio como resultado una significativa disminución de los índices investigados en relación con los valores de control y con BHT. Se concluyó que la actividad antioxidante de los ECG retrasó la oxidación y que se puede utilizar en la industria alimentaria para prevenir y reducir el deterioro de los lípidos del aceite

Adénome pléomorphe de l’espace parapharyngé

Les tumeurs de l’espace parapharyngé sont rares, elles représentent 0,5% de l’ensemble des tumeurs de la tête et du cou. elles sont bénignes dans 70 à 80 % des cas selon les séries. elles ont pour origine les glandes salivaires dans 40 à 50% des cas, dominés par les adénomes pléomorphes. Nous rapportons un cas d’adénome pléomorphe de l’espace parapharyngé chez une femme âgée de 38 ans. La patiente a été opérée par voie trans-orale avec exérèse complète de la tumeur. L’examen anatomopathologique définitif a conclu à un adénome pléomorphe. Les suites opératoires étaient simples. on n’a pas noté de récidive après un recul de 2 ans.Mots clés : tumeur para pharyngé, glandes salivaires, adénome pléomorphe

Carcinome parathyroidien

Parathyroid cancer is uncommon and its etiology is largely unknown. It is difficult to diagnose. The preoperative syndrome is unusually severe primary hyperparathyroidism. Intraoperatively, many characteristics of the tumor may be highly suggestive. Confirmation requires pathological analysis of the operative specimens and the diagnosis is strengthened in the presence of associated Shantz and Castelman criteria. Specific immunohistochemical techniques have been shown to be contributive. The diagnosis can be further supported by the clinical course of local recurrence or metastatic spread.Treatment of this tumor is primarly surgical. In some cases, postoperative radiotherapy may improve locoregional control of the tumor. The disease control can be monitored by regula assay of serum calcium and the parathormone. We report a case of parathyroid carcinoma, with special emphasis on the diagnostic modalities of this tumor, its treatmentand its prognosis.Keywords: Hypercalcemia, Primary Hyperparathyroidism, Parathyroid carcinoma, Surgery

Lung function profiles and aerobic capacity of adult cigarette and hookah smokers after 12 weeks intermittent training

Introduction: Pulmonary function is compromised in most smokers. Yet it is unknown whether exercise training improves pulmonary function and aerobic capacity in cigarette and hookah smokers and whether these smokers respond in a similar way as do non-smokers.Aim: To evaluate the effects of an interval exercise training program on pulmonary function and aerobic capacity in cigarette and hookah smokers.Methods: Twelve cigarette smokers, 10 hookah smokers, and 11 non-smokers participated in our exercise program. All subjects performed 30 min of interval exercise (2 min of work followed by 1 min of rest) three times a week for 12 weeks at an intensity estimated at 70% of the subject’s maximum aerobic capacity (VO2max). Pulmonary function was measured using spirometry, and maximum aerobic capacity was assessed by maximal exercise testing on a treadmill before the beginning and at the end of the exercise training program.Results: As expected, prior to the exercise intervention, the cigarette and hookah smokers had significantly lower pulmonary function than the non-smokers. The 12-week exercise training program did not significantly affect lung function as assessed by spirometry in the non-smoker group. However, it significantly increased both forced expiratory volume in 1 second and peak expiratory flow (PEF) in the cigarette smoker group, and PEF in the hookah smoker group. Our training program had its most notable impact on the cardiopulmonary system of smokers. In the non-smoker and cigarette smoker groups, the training program significantly improved VO2max (4.4 and 4.7%, respectively), v VO2max (6.7 and 5.6%, respectively), and the recovery index (7.9 and 10.5%, respectively).Conclusions: After 12 weeks of interval training program, the increase of VO2max and the decrease of recovery index and resting heart rate in the smoking subjects indicated better exercise tolerance. Although the intermittent training program altered pulmonary function only partially, both aerobic capacity and life quality were improved. Intermittent training should be advised in the clinical setting for subjects with adverse health behaviors.Keywords: cigarette smokers; hookah smokers; pulmonary function; aerobic capacity; interval trainin

Decomposition-based mission planning for fixed-wing UAVs surveying in wind

This paper presents a new method for planning fixed-wing aerial survey paths that ensures efficient image coverage of a large complex agricultural field in the presence of wind. By decomposing any complex polygonal field into multiple convex polygons, the traditional back-and-forth boustrophedon paths can be used to ensure coverage of these decomposed regions. To decompose a complex field in an efficient and fast manner, a top-down recursive greedy approach is used to traverse the search space in order to minimise flight time of the survey. This optimisation can be computed fast enough for use in the field. As wind can severely affect flight time, it is included in the flight time calculation in a systematic way using a verified cost function that offer greatly reduced survey times in wind. Other improved cost functions have been developed to take into account real world problems, e.g. No Fly Zones, in addition to flight time. A number of real surveys are performed in order to show the flight time in wind model is accurate, to make further comparisons to previous techniques and to show that the proposed method works in real-world conditions providing total image coverage. A number of missions are generated and flown for real complex agricultural fields. In addition to this, the wind field around a survey area is measured from a multi-rotor carrying an ultrasonic wind speed sensor. This shows that the assumption of steady uniform wind holds true for the small areas and time scales of a Unmanned Aerial Vehicle (UAV) aerial survey.</div

Tumeur Germinale De L\'espace Para Pharynge : A Propos D\'un Cas

Les tumeurs germinales à localisation cervico-faciale sont rares. Nous rapportons l\'observation d\'une une fillette de 7 ans porteuse d\'une tumeur maligne à cellules germinales de l\'espace para-pharyngé droit traité par chimiothérapie. Les particularités étiopathogéniques, thérapeutiques, et pronostiques de cette tumeur sont rappelées après une revue des données de la littérature.Extragonadal germ cell tumors of the head and neck are very rare. We report the case of a 7-year-old girl with malignant germ cell tumor of the right parapharyngeal space treated by chemotherapy. Etiopathogenic, therapeutic, and prognostic characteristics of this tumour are recalled after a review of the literature data. Keywords: Extragonadal germ cell tumors, parapharyngeal tumors. Journal Tunisien d\'ORL et de chirurgie cervico-faciale Vol. 18 2007: pp. 61-6

Teratome mature de la parotide : a propos d’une observation

Le tératome de la parotide est une malformation tumorale vestigiale rare contenant des dérivés plus ou moins différenciés, des trois feuillets embryonnaires. A la lumière d’une nouvelle observation et des données de la littérature, on se propose de mettre l’accent sur les aspects cliniques, histologiques et thérapeutiques de cette affection exceptionnelle dans cette localisation.Mots-clés : tératome, glande parotide, chirurgie, matureTeratoma of the parotid is a rare remnant malformation tumor containing undifferenciated derivatives of three germ layers. Through a new observation and literature review, authors proposed to focus on the clinical, histological and treatment of this lesion in this exceptionallocation.Key-words : teratoma, parotid gland, sugery, matur

Adenome pleomorphe a localisation extra-parotidienne

Objectives : Pleormorphic adenoma is a benign tumor of salivary gland. It mainly occurs in the parotid gland. The submandibular and minor salivary glands are rarely sites of occurrence. We describe the features of pleomorphic adenoma occurring at these sites.Material and methods: Between 2000 and 2009, 15 cases of pleomorphic adenoma occurring externly to the parotid have been collected.Results: Tumors were seen in the submandibular gland in 40 % of cases, in the hard palate in 33 % of cases, in the upper lip in 20 % of cases and in the parapharyngeal space in 7 % of cases. The mean age of patients was 48 years. The majority of cases were female. All patients were operated. We didn't report recurrence or malignants tumors after one year follow-up.Conclusion: After the parotid gland, the most common site of a pleomorphic adenoma is the submandibular gland followedby minor salivary gland of palate and lips. Each localisation has his clinical and therapeutic particularities.Key words : pleomorphic adenoma, submandibular gland, minor salivary glan

Cholesteatome Congenital De L’oreille Moyenne A Propos De Deux Cas

But :Le cholesteatome congenital de l’oreille moyenne est une entite rare. L’objectif de ce travail est de discuter les particularites cliniques et therapeutiques de cette pathologie a travers deux observations de malades presentant un cholesteatome congenital operes et suivis au service d’ORL et de chirurgie cervico-faciale Fattouma Bourguiba Monastir, entre 2002 et 2008. Résultats : Il s’agissait de deux garcons, ages de 5 et 7 ans. La symptomatologie etait dominee par l’apparition d’une hypoacousie et l’examen otologique a revele un tympan complet dans les deux cas. La TDM des rochers a permis d’evoquer le diagnostic du cholesteatome congenital et d’apprecier les extensions locales des lesions. Les deux malades ont eu une tympanoplastie en technique fermee. Conclusion : L’evolution du cholesteatome congenital est insidieuse et le diagnostic est souvent tardif. Le traitement est chirurgical, domine par la tympanoplastie en technique fermee. Mots clès : Chlolesteatome congenital, hypoacousie, tympan complet, tympanoplastie en technique fermee, technique ouverte