The End of the Conservatory” Pre-conferencia en LIX College Music Society Conference

Durante el mes de octubre de 2016 se desarrolló en Santa Fe, Nuevo México, Estados Unidos, la LIX Colle- ge Music Society Conference (Conferencia Nacional de la Sociedad Universitaria de Música), organización profesional que reúne en sus filas a los académicos del área de la música de universidades norteamericanas y extranjeras. Durante la conferencia se presentaron charlas,conciertos, presentaciones, mesas redondas, discusiones y coloquios sobre los más diversos temas relacionados con la innovación, investigación, y el análisis del estado actual de la educación musical a nivel de pre y postgrado. En esa ocasión, además tuve el honor de ser elegida entre un gran número de postulantes para ofrecer un recital con obras del compositor chileno Enrique Soro Barriga (1884-1954), el cual fue acogido con mucho interés y entusiasmo por todos los colegas asistentes. En ese contexto se llevó a cabo una jornada de talleres pre-conferencia denominada "The End of the Conservatory” (El final del conservatorio), y a eso me referiré en el presente texto

New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials.

Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a list of potential therapies. Here, we summarize significant new preclinical and early clinical developments in treatment of MPM, which include mesothelin specific antibody and toxin therapies, interleukin-4 (IL-4) receptor toxins, dendritic cell vaccines, immune checkpoint inhibitors, and gene-based therapies. In addition, several local modalities such as photodynamic therapy, postoperative lavage using betadine, and cryotherapy for local recurrence, have also shown to be effective for local control of disease

Results of Lung Cancer Screening in the Community.

PURPOSE: To address doubts regarding National Lung Screening Trial (NLST) generalizability, we analyzed over 6,000 lung cancer screenings (LCSs) within a community health system. METHODS: Our LCS program included 10 sites, 7 hospitals (2 non-university tertiary care, 5 community) and 3 free-standing imaging centers. Primary care clinicians referred patients. Standard criteria determined eligibility. Dedicated radiologists interpreted all LCSs, assigning Lung Imaging Reporting and Data System (Lung-RADS) categories. All category 4 Lung-RADS scans underwent multidisciplinary review and management recommendations. Data was prospectively collected from November 2013 through December 2018 and retrospectively analyzed. RESULTS: Of 4,666 referrals, 1,264 individuals were excluded or declined, and 3,402 individuals underwent initial LCS. Second through eighth LCSs were performed on 2,758 patients, for a total of 6,161 LCSs. Intervention rate after LCS was 14.6% (500 individuals) and was most often additional imaging. Invasive interventions (n = 226) were performed, including 141 diagnostic procedures and 85 surgeries in 176 individuals (procedure rate 6.6%). Ninety-five lung cancers were diagnosed: 84 non-small cell (stage 1: 60; stage 2: 7; stage 3: 9; stage 4: 8), and 11 small cell lung cancers. The procedural adverse event rate was 23/226 (10.1%) in 21 patients (0.6% of all screened individuals). Pneumothorax (n = 10) was the most frequent, 6 requiring pleural drainage. There were 2 deaths among 85 surgeries or 2.3% surgical mortality. CONCLUSIONS: Our LCS experience in a community setting demonstrated lung cancer diagnosis, stage shift, intervention frequency, and adverse event rate similar to the NLST. This study confirms that LCS can be performed successfully, safely, and with equivalence to the NLST in a community health care setting

REFLECTION OF SEMANTIC VECTORS OF CONSCIOUSNESS IN PROFESSIONAL AND LIFE-RELATED PROJECTS OF THE RUSSIAN STUDENTS

The article deals with the importance of building projects in professional and private life, allowing the person to adequately assess own capabilities, see the most expected things and the most desired things, determine the sequence of upcoming events, adequately distribute own energy etc. On the basis of empirical assessment of life-related projects built by students of the University the psychological description of their professional and life-related projects is given

THE NECESSITY OF THE PREVENTION OF CRISES OF PROFESSIONAL SELF-DETERMINATION OF PSYCHOLOGISTS AT THE STAGE OF HIGH SCHOOL TRAINING

Цель. В статье выявлены особенности переживания кризисов профессионального самоопределения студентов-психологов на разных этапах вузовского обучения.Методы исследования. Диагностика внутреннего конфликта Е.Б. Фанталовой.Результаты. В ходе исследования выявлена динамика кризисов профессионального самоопределения студентов-психологов в процессе вузовской подготовки, дана их содержательная характеристика, выявлены факторы, обусловливающие кризисы по годам их обучения, построена модель их профилактики.Выводы. Отмеченное по окончании формирующего этапа эксперимента сближение эталонов специалиста-психолога, формируемых у студентов в процессе вузовской подготовки и востребованных практикой, снижение уровня выраженности негативных психических проявлений, сопровождающих кризисы профессионального самоопределения студентов-психологов, позволяет говорить об эффективности реализованной программы психопрофилактики кризиса профессионального самоопределения.Goal. In the article are revealed the features of experience of crises of self-determination by students-psychologists at various stages of university education.Methods of research. Diagnosis of internal conflict by E.B. Fantalova.Results. During the study is revealed the dynamic of crises of professional self-determination of students-psychologists in the course of high school preparation, is given their substantial characteristic, are identified factors that contribute the crises by years of training, and is build a model of their prevention.Conclusions. The convergence of standards of specialists-psychologists marked by the end of the formative stage of the experiment, formed by students during the course of high school preparation and popular practices, reducing the severity of adverse psychiatric symptoms that accompany crises of professional self-determination of students-psychologists, let talk about the effectiveness of implemented programs of psychoprophylaxis crisis of professional self-determination

Evaluation of regional climate models ALARO-0 and REMO2015 at 0.22 degrees resolution over the CORDEX Central Asia domain

To allow for climate impact studies on human and natural systems, high-resolution climate information is needed. Over some parts of the world plenty of regional climate simulations have been carried out, while in other regions hardly any high-resolution climate information is available. The CORDEX Central Asia domain is one of these regions, and this article describes the evaluation for two regional climate models (RCMs), REMO and ALARO-0, that were run for the first time at a horizontal resolution of 0.22 degrees (25 km) over this region. The output of the ERA-Interim-driven RCMs is compared with different observational datasets over the 1980-2017 period. REMO scores better for temperature, whereas the ALARO-0 model prevails for precipitation. Studying specific subregions provides deeper insight into the strengths and weaknesses of both RCMs over the CAS-CORDEX domain. For example, ALARO-0 has difficulties in simulating the temperature over the northern part of the domain, particularly when snow cover is present, while REMO poorly simulates the annual cycle of precipitation over the Tibetan Plateau. The evaluation of minimum and maximum temperature demonstrates that both models underestimate the daily temper-ature range. This study aims to evaluate whether REMO and ALARO-0 provide reliable climate information over the CAS-CORDEX domain for impact modeling and environmental assessment applications. Depending on the evaluated season and variable, it is demonstrated that the produced climate data can be used in several subregions, e.g., temperature and precipitation over western Central Asia in autumn. At the same time, a bias adjustment is required for regions where significant biases have been identified

Wheat yield estimation from NDVI and regional climate models in Latvia

Wheat yield variability will increase in the future due to the projected increase in extreme weather events and long-term climate change effects. Currently, regional agricultural statistics are used to monitor wheat yield. Remotely sensed vegetation indices have a higher spatio-temporal resolution and could give more insight into crop yield. In this paper, we (i) evaluate the possibility to use Normalized Difference Vegetation Index (NDVI) time series to estimate wheat yield in Latvia and (ii) determine which weather variables impact wheat yield changes using both ALARO-0 and REMO Regional Climate Models (RCM) output. The integral from NDVI series (aNDVI) for winter and spring wheat fields is used as a predictor to model regional wheat yield from 2014 to 2018. A correlation analysis between weather variables, wheat yield and aNDVI was used to elucidate which weather variables impact wheat yield changes in Latvia. Our results indicate that high temperatures in June for spring wheat and in July for winter wheat had a negative correlation with yield. A linear regression yield model explained 71% of the variability with a residual standard error of 0.55 Mg/ha. When RCM data were added as predictor variables to the wheat yield empirical model a random forest approach resulted in better results compared to a linear regression approach, the explained variance increased up to 97% and the residual standard error decreased to 0.17 Mg/ha. We conclude that NDVI time series and RCM output enabled regional crop yield and weather impact monitoring at higher spatio-temporal resolutions than regional statistics