Deep excursion beyond the proton dripline. I. Argon and chlorine isotope chains

The proton-unbound argon and chlorine isotopes have been studied by measuring trajectories of their decay-in-flight products by using a tracking technique with micro-strip detectors. The proton (1p) and two-proton (2p) emission processes have been detected in the measured angular correlations “heavy-fragment”+p and “heavy-fragment”+p+p, respectively. The ground states of the previously unknown isotopes 30Cl and 28Cl have been observed for the first time, providing the 1p separation energies Sp of −0.48(2) and −1.60(8) MeV, respectively. The relevant systematics of 1p and 2p separation energies have been studied theoretically in the core+p and core+p+p cluster models. The first-time observed excited states of 31Ar allow to infer the 2p-separation energy S2p of 6(34) keV for its ground state. The first-time observed state in 29Ar with S2p = −5.50(18) MeV can be identified either as a ground or an excited state according to different systematics.Helmholtz Association grant IK-RU-002Helmholtz International Center for FAIR HIC for FAIRRussian Science Foundation grant No. 17-12-01367Polish National Science Center Contract No. UMO- 2015/17/B/ST2/00581Polish Ministry of Science and Higher Education Grant No. 0079/DIA/2014/43, Grant DiamentowyHelmholtz- CAS Joint Research Group grant HCJRG-10

Deep excursion beyond the proton dripline. II. Toward the limits of existence of nuclear structure

Prospects of experimental studies of argon and chlorine isotopes located far beyond the proton dripline are studied by using systematics and cluster models. The deviations from the widespread systematics observed in 28 , 29 Cl and 29 , 30 Ar have been theoretically substantiated, and analogous deviations have been predicted for the lighter chlorine and argon isotopes. The limits of nuclear structure existence are predicted for Ar and Cl isotopic chains, with 26 Ar and 25 Cl found to be the lightest sufficiently long-living nuclear systems. By simultaneous measurements of protons and γ rays following decays of such systems as well as their β -delayed emission, an interesting synergy effect may be achieved, which is demonstrated by the example of 30 Cl and 31 Ar ground-state studies. Such a synergy effect may be provided by the new EXPERT setup (EXotic Particle Emission and Radioactivity by Tracking) being operated inside the fragment separator and spectrometer facility at GSI, Darmstadt.Helmholtz Association de Alemania. IK-RU-002Russian Science Foundation. 17-12-01367Polish National Science Center. UMO2015/17/B/ST2/00581Polish Ministry of Science and Higher Education. 0079/DIA/2014/43Helmholtz- CAS Joint Research Group de Alemania. HCJRG-108Ministerio de Educación y Ciencia, España. FPA2016-77689-C2-1-RMinistry of Education, Youth and Sports de la República Checa. LTT17003 y LM201504

Motor activity of paramecium | Dvigatel'naia aktivnost' parametsii.

A systemic study of the mechanisms of motor activity of paramecium was carried out. The movements of paramecium responding to various influences were photographed. The analysis of the data revealed the time dependences of the rate of movement, rate of rotation, and the radius and the pitch of the helix trajectory. Mathematical models of the membrane and a unit that transforms the calcium signal to programs of regulating the effectors were constructed. A system of equations for constructing the trajectory of movement was proposed. It is concluded that the biomolecular system that involves calmodulin, calmodulin-dependent ionic channels, adenylate cyclase, guanylate cyclase, phosphodiesterases, Ca(2+)-calmodulin, cAMP, cGMP-dependent protein kinases, and phosphoprotein phosphatases is capable of regulating motor reactions necessary for complex maneuvering of paramecium under various conditions

Motor activity of paramecium

A systemic study of the mechanisms of motor activity of paramecium was carried out. The movements of paramecium responding to various influences were photographed. The analysis of the data revealed the time dependences of the rate of movement, rate of rotation, and the radius and the pitch of the helix trajectory. Mathematical models of the membrane and a unit that transforms the calcium signal to programs of regulating the effectors were constructed. A system of equations for constructing the trajectory of movement was proposed. It is concluded that the biomolecular system that involves calmodulin, calmodulin-dependent ionic channels, adenylate cyclase, guanylate cyclase, phosphodiesterases, Ca2+-calmodulin, cAMP, cGMP-dependent protein kinases, and phosphoprotein phosphatases is capable of regulating motor reactions necessary for complex maneuvering of paramecium under various conditions

Superconducting and magnetic properties of a new EuAsFeO0.85F0.15 superconductor

Polycrystalline samples of a new superconducting EuAsFeO0.85F0.15 compound with critical temperature Tc=11K were prepared by solid state synthesis. Its electric and magnetic properties have been investigated in magnetic fields from 0.1 to 140000 Oe. Critical magnetic fields Hc1, and Hc2 were measured and hence the magnetic penetration depths and the coherence length have been estimated. The temperature dependence Hc2 (T) exhibits clear hyperbolic - type behavior starting with the lowest fields. The data derived were used to estimate probable high Tc and Hc2 in compounds doped with rare-earths having small atomic radii.Comment: 12 pages, 10 figures, 13 reference

SCREENING OF RICE ACCESSIONS FOR GREENBUG RESISTANCE

During recent years the harmfulness of greenbug for rice crops has significantly increased. Laboratory experiments were conducted to study insect resistance of 200 accessions from the collection of the Donskoy Agrarian Scientific Center. The overwhelming majority of the studied forms were heterogeneous in their resistance. Twelve forms (5.5%) with the resistance score 2.2-3.0 were identified. The accessions NSH-1 (Hungary), ‘Musa Karem’ (Iran) and Zlatyi х Strelets (Russia) do not contain susceptible components and can be recommended as sources of aphid resistance for breeding rice varieties

Pharmacotherapy in a Multidisciplinary Paediatric Hospital: Polypharmacy and Drug–Drug Interaction Risk Illustrated with a Clinical Case

Nowadays, the problems caused by polypharmacy are recognised and widely discussed in the medical community. Multimorbidity, which is not uncommon in paediatric practice, comes with an increase in the number of prescriptions and necessitates an active search for tools to reduce the potential risk and frequency of adverse drug–drug interactions in paediatric patients.The aim of the study was to use a clinical case to illustrate the need for monitoring, including laboratory monitoring of pharmacokinetic parameters, during concomitant therapy in paediatric practice.Materials and methods: the study consisted in a retrospective analysis of the archived medical records of an 11-year-old child with nephrotic syndrome associated with a concomitant tuberculous process who had been receiving inpatient treatment with immunosuppressants at the Russian Children’s Clinical Hospital from May to July 2018.Results: the prescription of cyclosporine for nephrotic syndrome entailed monitoring of plasma drug levels for potential pharmacokinetic interactions with the medicinal products used to treat the concomitant disease. The monitoring revealed an interaction between cyclosporine and rifampicin at the level of biotransformation. An adjustment of the concomitant therapy (discontinuation of rifampicin) allowed for achieving the target blood cyclosporine concentration, decreasing proteinuria and hypercholesterolemia, and increasing the blood total protein level in the child, which indicated the effectiveness of the ongoing treatment for the chief complaint.Conclusions: the data obtained suggest that laboratory monitoring of pharmacokinetic parameters in paediatric polypharmacy can increase the effectiveness of therapy and prevent adverse reactions and irrational combination of medicinal products