Spatio-temporal patterns of recent and future climate extremes in the eastern Mediterranean and Middle East region

Recent and future changes in temperature and precipitation climate extremes are estimated using the Hadley Centre PRECIS ("Providing REgional Climates for Impacts Studies") climate model for the eastern Mediterranean and Middle East region. The area of interest is considered vulnerable to extreme climate events as there is evidence for a temperature rise while precipitation tends to decline, suggesting likely effects on vital socioeconomic sectors in the region. Observations have been obtained for the recent period (1961–1990) and used to evaluate the model output. The spatial distribution of recent temporal trends in temperature indicates strong increasing in minimum temperature over the eastern Balkan Peninsula, Turkey and the Arabian Peninsula. The rate of warming reaches 0.4–0.5 °C decade⁻¹ in a large part of the domain, while warming is expected to be strongest in summer (0.6–0.7 °C decade⁻¹) in the eastern Balkans and western Turkey. The trends in annual and summer maximum temperature are estimated at approximately 0.5 and 0.6 °C decade⁻¹ respectively. Recent estimates do not indicate statistically significant trends in precipitation except for individual sub-regions. Results indicate a future warming trend for the study area over the last 30 years of the 21st century. Trends are estimated to be positive and statistically significant in nearly the entire region. The annual trend patterns for both minimum and maximum temperature show warming rates of approximately 0.4–0.6 °C decade⁻¹, with pronounced warming over the Middle Eastern countries. Summer temperatures reveal a gradual warming (0.5–0.9 °C decade⁻¹) over much of the region. The model projects drying trends by 5–30% in annual precipitation towards the end of the 21st century, with the number of wet days decreasing at the rate of 10–30 days year⁻¹, while heavy precipitation is likely to decrease in the high-elevation areas by 15 days year⁻¹

Sedimentation processes and palaeographic evolution of Makrilia Pliocene deposits, SE Crete.

Η λεπτομερής ιζηματολογική ανάλυση των αποθέσεων της τομής Μακρυλιά, έδειξε την ύπαρξη τουλάχιστον 5 κύκλων ιζηματογένεσης με αυξανόμενο προς τα πάνω κοκκομετρικό μέγεθος που αναπτύχτηκαν σε ένα περιβάλλον υφαλοκρηπίδας. Η κύρια λιθολογία είναι αμμούχος πηλός και τα ιζήματα μεταφέρθηκαν ως ομογενές αιώρημα. Το ποσοστό του ανθρακικού ασβεστίου είναι χαμηλό και τείνει αυξανόμενο προς τα πιο αδρομερή κλάσματα. Οι μετρήσεις του οργανικού υλικού έδειξε την παρουσία αρκετών δειγμάτων με αυξημένο οργανικό υλικό προτείνοντας την ύπαρξη εν δυνάμει μητρικών πετρωμάτων για την γένεση υδρογονανθράκων. Η σχέση μεταξύ του ανθρακικού ασβεστίου και οργανικού υλικού είναι κύρια αρνητική προτείνοντας ανοξικές συνθήκες. Η βιοστρωματογραφική ανάλυση έδειξε Πλειοκαινική ηλικία των ιζημάτων που αποτέθηκαν σε εναλλασσόμενες οξικές – ανοξικές συνθήκες. Από τα παραπάνω αποτελέσματα και περνώντας υπόψη τα υπάρχοντα αποτελέσματα τωνιζημάτων που περιβάλλουν την περιοχή μελέτης φαίνεται πως οι μελετηθείσες αποθέσεις συγκεντρώθηκαν σε μια ρηχή με ήσυχα νερά ενδο-ορεινή λεκάνη στα περιθώρια της κύριας λεκάνης της Ιεράπετρας.Detailed sedimentological analysis in Makrylia cross-section deposits showed at least five coarsening-upward cycles that were developed in a shelf environment. The main lithology is sandy silt and the sediments were transported as homogenous suspension in a low energy environment that deposited in a shallow water basin. The content of calcium carbonate (CaCO3) is low and tends to increase to the coarsegrained clasts. Organic carbon (TOC) measurements showed the presence of many samples with high content in TOC suggesting potential hydrocarbon source rocks. There is mostly a negative correlation between CaCO3 and TOC introducing generally anoxic conditions. Biostratigraphic analysis showed that the studied deposits are of Pliocene age that were precipitated in alternating conditions of oxic- anoxic events. According to the above results and taking into account previous results from the surrounding sediments it seems that the studied deposits accumulated in a shallow, low energy, intra-mountain basin at the margins of the main Ierapetra basin

VisAge: Augmented reality for heritage

In this paper we describe the VisAge project, which explored how a community-based Augmented Reality (AR) system could be used to tell stories and cultural histories about urban environments. Our work focussed on two main themes - user engagement and immersiveness of the experience. To address the first theme, we developed an online portal where anybody could upload digital content and create their own stories using routes through a physical environment. To address the second theme, we developed a flexible, reconfigurable mobile platform to investigate different types and kinds of displays. The performance of the system was assessed in a series of workshops, which have provided insights to inform the development of future systems

Syndromic Forms of Hyperinsulinaemic Hypoglycaemia A 15-year follow-up Study

OBJECTIVE: Hyperinsulinaemic hypoglycaemia (HH) is one of the commonest causes of hypoglycaemia in children. The molecular basis includes defects in pathways that regulate insulin release. Syndromic conditions like Beckwith-Wiedemann (BWS), Kabuki (KS) and Turner (TS) are known to be associated with a higher risk for HH. This systematic review of children with HH referred to a tertiary centre aims at estimating the frequency of a syndromic/multisystem condition to help address stratification of genetic analysis in infants with HH. METHODS: We performed a retrospective study of 69 patients with syndromic features and hypoglycaemia in a specialist centre from 2004 to 2018. RESULTS: Biochemical investigations confirmed HH in all the cases and several genetic diagnoses were established. Responsiveness to medications and the final outcome following medical treatment or surgery were studied. CONCLUSIONS: This study highlights the association of HH with a wide spectrum of syndromic diagnoses and that children with features suggestive of HH-associated syndromes should be monitored for hypoglycaemia. If hypoglycaemia is documented, they should also be screened for possible HH. Our data indicate that most syndromic forms of HH are diazoxide-responsive and that HH resolves over time; however a significant percentage continues to require medications years after the onset of the disease. Early diagnosis of hyperinsulinism and initiation of treatment is important for preventing hypoglycaemic brain injury and intellectual disability

Spatial variability of precipitation regimes over Turkey

Turkish annual precipitation regimes are analysed to provide large-scale perspective and redefine precipitation regions. Monthly total precipitation data are employed for 107 stations (1963–2002). Precipitation regime shape (seasonality) and magnitude (size) are classified using a novel multivariate methodology. Six shape and five magnitude classes are identified, which exhibit clear spatial structure. A composite (shape and magnitude) regime classification reveals dominant controls on spatial variability of precipitation. Intra-annual timing and magnitude of precipitation is highly variable due to seasonal shifts in Polar and Subtropical zones and physiographic factors. Nonetheless, the classification methodology is shown to be a powerful tool that identifies physically-interpretable precipitation regions: (1) coastal regimes for Marmara, coastal Aegean, Mediterranean and Black Sea; (2) transitional regimes in continental Aegean and Southeast Anatolia; and (3) inland regimes across central and Eastern Anatolia. This research has practical implications for understanding water resources, which are under ever growing pressure in Turkey

How strongly programmed is a strong programme building?: A comparative analysis of outpatient clinics in two hospitals

Buildings are traditionally classified in Space Syntax theory as either strongly or weakly programmed. According to this theory, social life in strong programme buildings follows rules and requirements of the organisation, while space usage in weak programme buildings is assumed to follow spatial configuration. However, in recent studies it has been argued that weak programme buildings can show aspects of strong programming, too. This paper aims at a more detailed description of different levels of programming by identifying a set of criteria to differentiate between weak and strong programme. This is derived from early Space Syntax theories as well as from more recent contributions. These criteria are then applied to outpatient clinics in two hospitals using findings from an in-depth study of space usage as evidence. The main hypothesis to be tested is whether the two hospitals show different levels of programming, or are simply strongly programmed, as traditionally assumed in Space Syntax theory. Three different categories of users - physicians, nurses and clerks were observed and their work activities and interaction networks investigated. Results show that none of the two hospitals show aspects of strong programming only, but rather change from strong to weak depending on the different criteria. Moreover, none of the two cases is consistently stronger programmed than the other suggesting that the same building as well as the same building type can show different degrees of programming. The study provides an elaborate analysis of programming in buildings and thus offers a starting point for a renewed debate on programme in order to devise ways of quantifying the level of programming of buildings in the future, which to date has only been done qualitatively. It suggests that other complex building types should be studied and added to the analysis. The paper enhances our current understanding of how space usage patterns in complex buildings evolve and contributes to the articulation of one of the key theoretical concepts in Space Syntax

Mediated Spatial Narratives: Experiencing Archival Material and Shared Memories in Urban Space

In this paper we report on studies we conducted focusing on the use of Augmented Reality to annotate real sites with relevant archival content. This is an interdisciplinary study of novel interactive technologies and supportive platforms such as geolocation-navigation and contextual digital augmentation of archival material in public spaces. We involved community volunteers, experts and public in a participatory heritage initiative. We designed an experience that supported a multi-platform participation, via an online geo-tagging portal and a mixed reality navigational experience. In an iterative design process we explored the use and preference of mobile devices, the controlled design of digital content anchored to real sites and the use of AR to support urban narratives. We did this by conducting a series of user walkthroughs with recruited participants and workshops with local experts related to the case studies. In this paper we argue on the importance of situating urban experience of digital archives and stories in the actual locations of the events they represent as to better support immersion, enhance place experience and reinforce situated learning. Our work contributes to the design of hybrid spatialities and experiences in urban space that relate to local memory and culture

What You Find Depends on How You Measure It: Reactivity of Response Scales Measuring Predecisional Information Distortion in Medical Diagnosis

“Predecisional information distortion” occurs when decision makers evaluate new information in a way that is biased towards their leading option. The phenomenon is well established, as is the method typically used to measure it, termed “stepwise evolution of preference” (SEP). An inadequacy of this method has recently come to the fore: it measures distortion as the total advantage afforded a leading option over its competitor, and therefore it cannot differentiate between distortion to strengthen a leading option (“proleader” distortion) and distortion to weaken a trailing option (“antitrailer” distortion). To address this, recent research introduced new response scales to SEP. We explore whether and how these new response scales might influence the very proleader and antitrailer processes that they were designed to capture (“reactivity”). We used the SEP method with concurrent verbal reporting: fifty family physicians verbalized their thoughts as they evaluated patient symptoms and signs (“cues”) in relation to two competing diagnostic hypotheses. Twenty-five physicians evaluated each cue using the response scale traditional to SEP (a single response scale, returning a single measure of distortion); the other twenty-five did so using the response scales introduced in recent studies (two separate response scales, returning two separate measures of distortion: proleader and antitrailer). We measured proleader and antitrailer processes in verbalizations, and compared verbalizations in the single-scale and separate-scales groups. Response scales did not appear to affect proleader processes: the two groups of physicians were equally likely to bolster their leading diagnosis verbally. Response scales did, however, appear to affect antitrailer processes: the two groups denigrated their trailing diagnosis verbally to differing degrees. Our findings suggest that the response scales used to measure information distortion might influence its constituent processes, limiting their generalizability across and beyond experimental studies

Exploring the effect of spatial layout on mediated urban interactions

In this paper we focus on the spatial configuration and emergent social interactions in two locations in London mediated by interactive and networked urban displays. Our analysis draws upon interactions mediated through displays we implemented in the real world connecting four urban spaces [1]. We outline our case study and the methodology we implemented, including the analysis of the spatial layout on the micro/local scale in two sites, followed by the observations of social behavior and technologically mediated interactions by actors, spectators and passers-by during two community events, before finally outlining the following identified interaction zones: 1) direct interaction space surrounding the display (direct); 2) the surrounding public space (wide); and 3) across spatial boundaries i.e. the remotely connected space through networked displays (connected) over time. We highlight site-specific interactions and compare them to the more generic types of interactions, thus contributing to the understanding of mediated social interactions. We suggest that the properties of the spatial layout play a significant role and, to a certain extent, frame the type of interactions mediated through public displays. We highlight in particular the dynamic and interconnected nature of this mediation, defined through the spatial layout, people, type of social activities, and time of the day