35 research outputs found
Intercostal lung herniation mimicking retroperitoneal bleeding in a patient with obstructive sleep apnea treated with continuous positive-pressure ventilation
Abdominal pain : diagnostic issues in patient with coexisting Takayasu's arteritis and ulcerative colitis
Cytomegalovirus gastroenteritis with pyloric stenosis and persistent malabsorption in a patient with common variable immunodeficiency
Kimura disease and immunoglobulin G4-related disease : a possible overlap in a patient with severe systemic symptoms
Granulomatosis with polyangiitis (Wegener's granulomatosis) with hard palate and bronchial perforations treated with rituximab : a case report
We present a case of a 57-year-old woman suffering from granulomatosis with polyangiitis (GPA), who in the seventh months of immunosuppressive treatment (cyclophosphamide) progressed with new pulmonary changes and perforations of the hard palate and bronchi. Rituximab was introduced resulting in B-cell depletion and disappearance of anti-PR3 antibody. Palatal holes have substantially diminished and all bronchial perforations disappeared, covered by fibrous tissue. In the fourth month after rituximab administration, large scarring obstruction of the right main bronchus with upper and middle lobes atelectasis emerged. Because of increasing dyspnoea, stenotic bronchus was re-opened by bronchoscopy. Intervention was complicated by bilateral pneumothorax and later, on the seventh day, by fatal pulmonary bleeding. To our knowledge, this is the first report of GPA refractory to cyclophosphamide complicated by palatal and bronchial perforations
Cough-induced lung intercostal hernia
A 73-year-old male with marked emphysema was admitted to the 2nd Department of Internal Medicine, University Hospital in Krakow because of chronic obstructive pulmonary disease (COPD) exacerbation. His medical history was significant for total laryngectomy due to laryngeal cancer in 2010