212 research outputs found

    Conditional BRUNO: A neural process for exchangeable labelled data

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    We present a neural process that models exchangeable sequences of high-dimensional complex observations conditionally on a set of labels or tags. Our model combines the expressiveness of deep neural networks with the data-efficiency of Gaussian processes, resulting in a probabilistic model for which the posterior distribution is easy to evaluate and sample from, and the computational complexity scales linearly with the number of observations. The advantages of the proposed architecture are demonstrated on a challenging few-shot view reconstruction task which requires generalisation from short sequences of viewpoints

    Perspective directions in the development of architecture of the polytechnic museums

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    The museums of science and technology (or polytechnic) highlight the process of the innovational development of the society and have their own place in the system of school-science-industry-technical culture. The innovational activity of certain regions, states or groups of states is comprised of inventions, discoveries, new products and technologies that is all that provides the development of society and its competitive advantages. The modern polytechnic museums combine not only the functions of the demonstration of the achievements of the scientific and technological progress but also training and development of new inventions. In connection with the multifunctional nature of the modern polytechnic museum architects face the challenge of the creation of the architecture with universal dimensional planning elements, with its possible transformation in the course of time.Keywords: museum; science; innovations; technology; typolog

    New personalized genetic mouse model of Lesch-Nyhan syndrome for pharmacology and gene therapy

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    In the current study, we present the results of the generation of a genetically modified mouse strain carrying a deletion in the HPRT1 gene. These mice can be effectively used for the preclinical testing of new drugs aimed at the treatment of Lesch-Nyhan syndrom

    Neyrodoz in the treatment of secondary premature ejaculation in patients with chronic prostatitis

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    Premature ejaculation (PE) is the type of sexual dysfunction, which is characterized by constant or nearly constant uncontrolled ejaculation before vaginal penentration or within minutes of the start of sexual intercourse, that causing a feeling of sexual dissatisfaction and leading to sexual frustration among the partners. It has been shown that the antimicrobial and antiinflammatory therapy of chronic prostatitis (CP) increases the duration of sexual intercourse and improves the control over the ejaculation. PE in the patients with CP may be an independent sexual disorder that may require a specific correction. Antidepressants are the first line of drugs in the treatment of PE according to the recommendations of the European Association of Urology. However, some patients refuse to intake this medicine. The aim of our study was to evaluate the clinical efficacy and safety of Neyrodoz in the treatment of PE in patients with CP.Materials and methods. The study included 32 patients (mean age 37.5 years) who have had complains on PE after the treatment of CP. All the patients were randomly selected into two groups. 1st – basic group (n = 15) and 2nd – control group (n = 17).The first group patients intook Neyrodoz 2 capsules twice a day. The second group got placebo in the same dose during 30 days.Results. The time of intravaginal latency increased from 40,8 ± 9,9 (25–56) to180,1± 41,2 (120–240) seconds in patients of the 1st group after the therapy. The score of tool-PEDT decreased from 15,8 ± 3,1 (11–20) to 3,9 ± 2,9 (0–8). The visual analogue scale (VAS) symptoms improved from 8,6 ± 1,4 (6–10) to 2,5 ± 2,1 (0–5). The time of intravaginal latency increased from 38,4 ± 10,0 (25–59) to 40,7 ± 7,4 (35–59) seconds in 14 of 17 men in the second group of patients. The score of tool-PEDT decreased from 15,6 ± 2,8 (11–20) to 14,3 ± 2,7 (12–19). The VAS symptoms improved from 8,9 ± 1,3 (6–10) to 8,5 ± 1,7 (6–10).Conclusions. Neyrodoz is an effective and safe medicine to the correction of PE in patients with CP, who did not get an effect after the treatment of CP

    SCREENING OF STRAINS OF REGIONAL SPECIALIZED COLLECTION ALKANOTROPHIC MICROORGANISMS TO RESISTANCE OF ORGANIC SOLVENTS

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    Bacterial tolerance and ability to adapt to organic solvents can be of valuable importance in biocatalytic and bioremediation processes. Rhodococcus strains have high resistant to hydrocarbon compounds. The studies have shown different ability to survive and morphological characteristics of cells Rhodococcus after reaction with n-decane, n-hexane, 1-butanol and ethanol.Работа выполнена в рамках Государственного задания Минобрнауки России 6.1194.2014/K

    BIOFUELS THIRD GENERATION

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    The paper describes the main aspects of microalgae usage in fuel production. The shortcomings of existing methods of biofuel production are shown. There is a need to develop new optimal economically justified microalgae cultivation technologies.В работе рассмотрены основные аспекты применения микроводорослей в производстве топлива. Приведены недостатки существующих способов производства биотоплива. Отмечена необходимость разработки новых оптимальных, экономически обоснованных технологий культивирования микроводорослей

    Bruno: A deep recurrent model for exchangeable data

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    We present a novel model architecture which leverages deep learning tools to perform exact Bayesian inference on sets of high dimensional, complex observations. Our model is provably exchangeable, meaning that the joint distribution over observations is invariant under permutation: this property lies at the heart of Bayesian inference. The model does not require variational approximations to train, and new samples can be generated conditional on previous samples, with cost linear in the size of the conditioning set. The advantages of our architecture are demonstrated on learning tasks that require generalisation from short observed sequences while modelling sequence variability, such as conditional image generation, few-shot learning, and anomaly detectio

    Model of vocational school, high school and manufacture integration in the regional system of professional education

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    © 2015, Canadian Center of Science and Education. All rights reserved. Integration of vocational, high schools and manufacture contributes to qualified personnel for the regional oil industry effective training. So this article is aimed at the model development of vocational, high school and manufacture integration in the regional system of vocational education. The basic approach to the structural-functional model development of vocational, high school and manufacture integration in the regional system of vocational education is an integrative one, taking into consideration the integrated system “vocational school-high school-manufacture” components in their unity and cooperation, giving it the integrity and structural and functional stability. Structural-functional model of vocational, high school and manufacture integration in the regional system of vocational education includes functional-target, organizational-structural, content, process and result components
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