The infrastructure of public catering in the context of tourist city space development

To assess the impact of environmental factors on the activities of catering enterprises of the Belgorod region and the quality of customer service, the authors proposed a method using STEP-analysis and SWOT-analysis. The analysis of environmental factors was carried out on the basis of the expert evaluation results conducted in two stage

Transformation of museum product

Today, each museum needs to develop an active strategy of market development, which is preceded by a comprehensive analysis of potential consumers of the museum product, on the basis of which the directions of development will be proposed. The conducted research allowed us to reveal a number of problems which are connected with necessity of transformation of the museum product providing satisfaction of visitor’s requirements and, at the same time, increase in the income of the museu

Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation in vitro and in vivo

BACKGROUND: The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are one of the major sources of reactive oxygen species during cold stress. Recently it has been suggested that uncoupling of oxidation and phosphorylation in mitochondria during oxidative stress can decrease ROS formation by mitochondrial respiratory chain generation. At the same time, it is known that plant uncoupling mitochondrial protein (PUMP) and other UCP-like proteins are not the only uncoupling system in plant mitochondria. All plants have cyanide-resistant oxidase (AOX) whose activation causes an uncoupling of respiration and oxidative phosphorylation. Recently it has been found that in cereals, cold stress protein CSP 310 exists, and that this causes uncoupling of oxidation and phosphorylation in mitochondria. RESULTS: We studied the effects of CSP 310-like native cytoplasmic proteins from a number of cereal species (winter rye, winter wheat, Elymus and maize) on the energetic activity of winter wheat mitochondria. This showed that only CSP 310 (cold shock protein with molecular weight 310 kD) caused a significant increase of non-phosphorylative respiration. CSP 310-like proteins of other cereals studied did not have any significant influence on mitochondrial energetic activity. It was found that among CSP 310-like proteins only CSP 310 had prooxidant activity. At the same time, Elymus CSP 310-like proteins have antioxidant activity. The study of an influence of infiltration by different plant uncoupling system activators (pyruvate, which activates AOX, and linoleic acid which is a substrate and activator for PUMP and CSP 310) showed that all of these decreased lipid peroxidation during cold stress. CONCLUSIONS: Different influence of CSP 310-like proteins on mitochondrial energetic activity and lipid peroxidation presumably depend on the various subunit combinations in their composition. All the plant cell systems that caused an uncoupling of oxidation and phosphorylation in plant mitochondria can participate in plant defence from oxidative damage during cold stress

Automated Information System for Personnel Training in the Field of Professional Education

Рассматривается концепция автоматизированной информационной системы, которую можно использовать в сфере профессионального образования для подготовки кадров. Приведена классификация необходимой ERP-системы. Выведены основные особенности подготовки кадров в цифровом производстве.The concept of an automated information system that can be used in the field of education for staff training is considered. The classification of the ERP system is given. The main features of staff training in digital production are formulated

Study of the composition of potatoes by agronomic traits determining its suitability for industrial processing

The study of biochemical quality indicators of 26 new potato hybrids was carried out in order to determine the ones mostly suitable for processing into starch and potato products and for use as table variety. An express method was used to determine dry matter (DM), Evers method was used to determine the total starch content of tubers, the polarimetric method and a glucometer test were used to determine reducing sugars, glycoalkaloids and inorganic phosphorus were determined by spectrophotometric method. There have been selected 5 hybrids suitable for industrial processing and as a source material for breeding. One potato hybrid with 25,06 % content of DM, more than 18,22 % of starch met the requirements for potatoes used for processing into starch and starch products; another potato hybrid can be recommended for the production of fried potato products according to the parameters: DM – 22.40 % starch – 16.18 %, reducing sugars – 0.23 %, glycoalkaloids – 62,0 mg/kg. Three of the studied hybrids with the content of DM of more than 22 %, starch not less than 16%, reducing sugars 0.2-0.4 % and glycoalkaloids 60-126 mg / kg may be used for the production of other types of potato products. The rest of the hybrids can only be recommended for use as table potatoes. The relationship between indicators affecting the quality of potato products has been revealed. Correlations were established between the mass fractions of: dry matter and starch in the tuber (r = 0.98) – high correlation; reducing sugars and glycoalkaloids (r = 0.68); tuber dry matter and glycoalkaloids (r = 0.59); dry matter and glucose (r = -0.61); starch and glucose (r = -0.58) – average correlations. It has been established that the mass fraction of reducing sugars and the direction of rotation of the plane of polarization of light by sugars change non-linearly under different temperature conditions of sample storage

Theoretical Justification of the Use Smart-Technologies in Eco-Projects

The article discusses the use of smart technologies in the creation of scavenger robots. Various inventions in this field are considered. The main technical characteristics are given. Conclusions are drawn.В статье рассматривается использование smart-технологий при создании роботов-мусорщиков. Рассмотрены различные изобретения в этой области. Приведены основные технические характеристики. Сделаны выводы

Diabetes mellitus associated with the mutation of the ABCC8 gene (MODY 12): features of clinical course and therapy

Maturity-Onset Diabetes of the Young (MODY) is a heterogeneous group of diseases associated with genes mutations leading to dysfunction of pancreatic β-cells. Among the 14 identified MODY variants, MODY 1–5 are the most studied. The article reports a MODY 12 clinical case, with mutation in ABCC8, encoding the sulphonylurea receptor. Diabetes mellitus manifested in a 27-year-old man with hyperglycaemia up to 24 mmol/L, without ketosis. Non-proliferative diabetic retinopathy, microalbuminuria, dyslipidaemia and carotid atherosclerosis were revealed upon initial examination. The levels of pancreatic islet cell antibodies and glutamate decarboxylase antibodies were negative, while the level of C-peptide was within the normal range. Insulin therapy in the basal-bolus regimen was provided with a gradual dose reduction due to frequent hypoglycaemia. The preproliferative retinopathy with macular oedema was revealed after 4 months of therapy, and panretinal photocoagulation of both eyes was performed. A molecular genetics study revealed a mutation in the gene ABCC8, the same mutation was found in patient’s mother and uncle. Insulin therapy was cancelled, and the treatment of gliclazide MR 60 mg/day was initiated, which resulted in extreme glycaemic excursions. Thereby, sodium–glucose cotranporter-2 (SGLT2) inhibitor dapagliflozin 10 mg/day was added. A reduction in glucose variability parameters were observed on combination therapy. After 6 months till 1.5 years of treatment, glycaemic control was optimal, no hypoglycaemic episodes were observed. This case study demonstrates clinical features of MODY 12, and the potential of combination of sulfonylurea and SGLT2 inhibitor in the treatment of this disease

Papillomatosis of the largent in children's age. Use of argon plasma in surgical treatment

The purpose of the study. Case history review of a patient with a benign laryngeal mass with the use of modern surgical treatment techniques.Цель исследования. Разбор истории болезни больного с доброкачественным образованием гортани с применением современной методики хирургического лечения

Ce-doped Li6Ln(BO3)3 (Ln = Y, Gd) Single crystals fibers grown by micro-pulling down method and luminescence properties

Ce3+-doped borate crystal fibers of Li6Gd(BO 3)3 (LGBO) and Li6Y(BO3)3 (LYBO) compositions are grown by the micro-pulling down (μ-PD) method for potential application in developing new neutron detectors. The ternary equilibrium diagram of Li2O-Gd2O3-B 2O3 is drawn and the preparations of homogeneous mixed LGBO and LYBO powders and growth conditions for single crystal fibers are discussed. Absorption, excitation and X-ray luminescence spectra are investigated. Absolute light yield derived from energy spectra and kinetic decay curves measured under α- and γ-scintillations of Ce 3+-doped LGBO and LYBO single crystal fibers is provided. © 2012 Elsevier B.V. All rights reserved

Double Spin Asymmetries A_NN and A_SS at sqrt{s}=200 GeV in Polarized Proton-Proton Elastic Scattering at RHIC

We present the first measurements of the double spin asymmetries A_NN and A_SS at sqrt{s}=200 GeV, obtained by the pp2pp experiment using polarized proton beams at the Relativistic Heavy Ion Collider (RHIC). The data were collected in the four momentum transfer t range 0.01<|t|<0.03 (GeV/c)^2. The measured asymmetries, which are consistent with zero, allow us to estimate upper limits on the double helicity-flip amplitudes phi_2 and phi_4 at small t as well as on the difference Delta(sigma_T) between the total cross sections for transversely polarized protons with antiparallel or parallel spin orientations.Comment: 13 pages with 3 figures. Final version accepted by Phys. Lett.