In Reply : Body Mass Index and the Risk of Poor Outcome in Surgically Treated Patients With Good-Grade Aneurysmal Subarachnoid Hemorrhage

Peer reviewe

Maternal prenatal mood problems and lower maternal emotional availability associated with lower quality of child's emotional availability and higher negative affect during still-face procedure

Our aim was to study the effects of maternal perinatal mood and maternal emotional availability on child emotional availability and negative affect during the still-face procedure (SFP). The sample included 214 women who participated in a prospective study. We assessed maternal mood problems using the Mini International Neuropsychiatric Interview and PRAQ questionnaire during pregnancy and using STAI and EPDS questionnaires during pregnancy and at 6 months after delivery. Maternal and child emotional availability were studied using the Emotional Availability Scales during the SFP at 6 months. We observed and quantified child's negative affect during SFP episodes. We found that mothers with maternal mood problems (anxiety and/or depression) during pregnancy, but not postnatally, showed less optimal maternal structuring during the SFP, and the children showed lower involvement and responsiveness during interactions with their mothers. Furthermore, lower maternal emotional availability was related to the child's higher negative affect during the SFP. Our findings underline the independent roles of both prenatal stress exposure and maternal caregiving behavior in a child's socioemotional development

Fast computation of the geoelectric field using the method of elementary current systems and planar Earth models

International audienceThe method of spherical elementary current systems provides an accurate modelling of the horizontal component of the geomagnetic variation field. The interpolated magnetic field is used as input to calculate the horizontal geoelectric field. We use planar layered (1-D) models of the Earth's conductivity, and assume that the electric field is related to the local magnetic field by the plane wave surface impedance. There are locations in which the conductivity structure can be approximated by a 1-D model, as demonstrated with the measurements of the Baltic Electromagnetic Array Research project. To calculate geomagnetically induced currents (GIC), we need the spatially integrated electric field typically in a length scale of 100km. We show that then the spatial variation of the electric field can be neglected if we use the measured or interpolated magnetic field at the site of interest. In other words, even the simple plane wave model is fairly accurate for GIC purposes. Investigating GIC in the Finnish high-voltage power system and in the natural gas pipeline, we find a good agreement between modelled and measured values, with relative errors less than 30% for large GIC values. Key words. Geomagnetism and paleomagnetism (geomagnetic induction; rapid time variations) ? Ionosphere (electric field and currents

SIFAT KIMIA TANAH PADA HUTAN MANGROVE DI DESA TOLAI BARAT KECEMATAN TORUE KABUPATEN PARIGI MOUTONG

Mangrove forest vegetation in Indonesia is known for its high species diversity. Diverse mangrove vegetation can provide a good contribution to the soil including soil chemical properties such as soil pH, C-organic, nitrogen, phosphorus, potassium and cation exchange capacity. This research was conducted from January to March 2019, located in the West Tolai Village, Torue District, Parigi Moutong Regency. The purpose of this study was to determine the chemical nature of the soil in mangrove forests in Tolai Barat Village, Torue District, Parigi Moutong Regency. The method used is the survey / observation method and soil sampling is done intentionally (purposive sampling). Sampling was carried out in 3 different conditions, which were always inundated, inundated at moderate tides and inundated at high tides at depths of 0-30 and 30-60 cm, and at each point 3 samples were taken so that a total of 18 samples were composite into 6 the sample. Soil samples are then analyzed in the soil science laboratory. The results of this study indicate that the chemical properties of the soil in the mangrove forest of Tolai Barat Village are very diverse in the three different location conditions, which are always inundated, flooded during medium tides and submerged during high tides with depths of 0-30 and 30-60 respectively. cm has a acidic and neutral soil pH with a value of 4.74 -7.46H2O, C-organic from very low to high 0.45-4.75%, N-Total from moderate to low 0.21-0.05%, P-available is very low 9.11-7.94 ppm, K-Total with low to moderate values 15.89-23.18mg100gr-1, Cation Exchange Capacity (CEC) is classified as very low to low 4.16 -5.88 (cmol (+) kg-1)

An educational intervention for NICU staff decreased maternal postpartum depression

BackgroundMothers of preterm infants are at increased risk for postpartum depression, which may disturb parenting and child development. Strategies for prevention are needed. Therefore, we evaluated how an educational intervention for neonatal staff affected depression symptoms among mothers of preterm infants.MethodsThe Close Collaboration with Parents intervention was implemented in the NICU at Turku University Hospital in Finland. Maternal depression was compared between the pre-intervention and post-intervention cohorts using the Edinburgh Postnatal Depression Scale. The eligible infants were born ≤1500 g without major anomalies and survived. Data were available from 145 and 93 mothers in the pre-intervention and post-intervention cohorts, respectively, at 4 and/or 6 months of corrected age.ResultsThe depression scores were significantly lower in the post-intervention cohort than in the pre-intervention cohort; the estimated difference was 2.54 points (95% CI, 1.24–3.83), p p = 0.066.ConclusionThe Close Collaboration with Parents intervention decreased depression symptoms among the mothers of very preterm infants. Systematic educational intervention targeted to the whole NICU staff can potentially prevent postnatal depression among mothers of preterm infants.</p

Screening tools for early neuropsychological impairment after aneurysmal subarachnoid hemorrhage

Background Although most aneurysmal subarachnoid hemorrhage (aSAH) patients suffer from neuropsychological disabilities, outcome estimation is commonly based only on functional disability scales such as the modified Rankin Scale (mRS). Moreover, early neuropsychological screening tools are not used routinely. Objective To study whether two simple neuropsychological screening tools identify neuropsychological deficits (NPDs), among aSAH patients categorized with favorable outcome (mRS 0-2) at discharge. Methods We reviewed 170 consecutive aSAH patients that were registered in a prospective institutional database. We included all patients graded by the mRS at discharge, and who had additionally been evaluated by a neuropsychologist and/or occupational therapist using the Montreal Cognitive Assessment (MoCA) and/or Rapid Evaluation of Cognitive Function (ERFC). The proportion of patients with scores indicative of NPDs in each test were reported, and spearman correlation tests calculated the coefficients between the both neuropsychological test results and the mRS. Results Of the 42 patients (24.7%) that were evaluated by at least one neuropsychological test, 34 (81.0%) were rated mRS 0-2 at discharge. Among these 34 patients, NPDs were identified in 14 (53.9%) according to the MoCA and 8 (66.7%) according to the ERFC. The mRS score was not correlated with the performance in the MoCA or ERFC. Conclusion The two screening tools implemented here frequently identified NPDs among aSAH patients that were categorized with favorable outcome according to the mRS. Our results suggest that MoCA or ERFC could be used to screen early NPDs in favorable outcome patients, who in turn might benefit from early neuropsychological rehabilitation.Peer reviewe

The association of maternal-fetal attachment with smoking and smoking cessation during pregnancy in The FinnBrain Birth Cohort Study

BackgroundSmoking in pregnancy constitutes a preventable risk factor for fetal/child development and maternal-fetal attachment (MFA) seems to contain a momentum that can break the chain of adverse outcomes by promoting maternal prenatal health practices. This study aimed to explore the association of MFA with smoking at any time during pregnancy and smoking cessation in early pregnancy, and the modifying role of MFA on the expected effects of education and prenatal psychological distress (PPD) on prenatal smoking behavior.MethodsThe pregnant women (n=3766) participated in the The FinnBrain Birth Cohort Study in Finland between December 2011 and April 2015. The binary outcomes, smoking at any time during pregnancy and smoking cessation in early pregnancy, were obtained from self-reports at gestational weeks (gwks) 14 and 34 and The Finnish Medical Birth Register. MFA was assessed with the Maternal-Fetal Attachment Scale (MFAS) at gwks 24 and 34. Logistic regression analyses were used to determine the association between MFA and maternal prenatal smoking behavior.FindingsThe prevalence of smoking was 16.5%, and 58.1% of the smokers quit smoking during pregnancy. The independent associations of total MFA scores with prenatal smoking behavior were not established (aOR=1.00-1.02, multiplicity adjusted p>0.05). A higher score in the altruistic subscale of MFA, Giving of self, associated with a higher probability of smoking cessation (24 gwks: aOR=1.13, 95% CI [1.04, 1.24], p=0.007, multiplicity adjusted p=0.062; 34 gwks: aOR=1.17, 95% CI [1.07, 1.29], p<0.001, multiplicity adjusted p=0.008). The modifying effect of MFA on the observed associations between PPD and smoking in pregnancy and between maternal education and smoking in pregnancy / smoking cessation in early pregnancy was not demonstrated. ConclusionsThe altruistic dimension of maternal-fetal attachment associates with an increased probability of smoking cessation during pregnancy and therefore strengthening altruistic maternal-fetal attachment may constitute a promising novel approach for interventions aiming at promoting smoking cessation during pregnancy

Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma

<p>Abstract</p> <p>Background</p> <p>The expression of a neural crest stem cell marker, polysialic acid (polySia), and its main carrier, neural cell adhesion molecule (NCAM), have been detected in some malignant tumors with high metastatic activity and unfavorable prognosis, but the diagnostic and prognostic value of polySia-NCAM in neuroblastoma is unclear.</p> <p>Methods</p> <p>A tumor tissue microarray (TMA) of 36 paraffin-embedded neuroblastoma samples was utilized to detect polySia-NCAM expression with a polySia-binding fluorescent fusion protein, and polySia-NCAM expression was compared with clinical stage, age, <it>MYCN </it>amplification status, histology (INPC), and proliferation index (PI).</p> <p>Results</p> <p>PolySia-NCAM-positive neuroblastoma patients had more often metastases at diagnosis, and polySia-NCAM expression associated with advanced disease (<it>P </it>= 0.047). Most interestingly, absence of polySia-NCAM-expressing tumor cells in TMA samples, however, was a strong unfavorable prognostic factor for overall survival in advanced disease (<it>P </it>= 0.0004), especially when <it>MYCN </it>was not amplified. PolySia-NCAM-expressing bone marrow metastases were easily detected in smears, aspirates and biopsies.</p> <p>Conclusion</p> <p>PolySia-NCAM appears to be a new clinically significant molecular marker in neuroblastoma, hopefully with additional value in neuroblastoma risk stratification.</p