Experience of electronic educational resources application in teaching medical University students

The article describes the experience of using electronic educational resources for mastering the main educational professional program in the disciplines "Microbiology", "Microbiology, Virology", "Microbiology, Virology, Immunology" by students of the medical university. The advantages of the ESM for self-training of students are indicatedВ статье изложен опыт применения электронных образовательных ресурсов для освоения основной образовательной профессиональной программы по дисциплинам «Микробиология», «Микробиология, вирусология», «Микробиология, вирусология, иммунология» студентами медицинского университета. Обозначены преимущества электронного образовательного ресурса (ЭОР) для самостоятельной подготовки обучающихс

Assessment of the quality of measures of child oral health-related quality of life

Background Several measures of oral health-related quality of life have been developed for children. The most frequently used are the Child Perceptions Questionnaire (CPQ), the Child Oral Impacts on Daily Performances (C-OIDP) and the Child Oral Health Impact Profile (COHIP). The aim of this study was to assess the methodological quality of the development and testing of these three measures. Methods A systematic search strategy was used to identify eligible studies published up to December 2012, using both MEDLINE and Web of Science. Titles and abstracts were read independently by two investigators and full papers retrieved where the inclusion criteria were met. Data were extracted by two teams of two investigators using a piloted protocol. The data were used to describe the development of the measures and their use against existing criteria. The methodological quality and measurement properties of the measures were assessed using standards proposed by the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) group. Results The search strategy yielded 653 papers, of which 417 were duplicates. Following analysis of the abstracts, 119 papers met the inclusion criteria. The majority of papers reported cross-sectional studies (n = 117) with three of longitudinal design. Fifteen studies which had used the original version of the measures in their original language were included in the COSMIN analysis. The most frequently used measure was the CPQ. Reliability and construct validity appear to be adequate for all three measures. Children were not fully involved in item generation which may compromise their content validity. Internal consistency was measured using classic test theory with no evidence of modern psychometric techniques being used to test unidimensionality of the measures included in the COSMIN analysis. Conclusion The three measures evaluated appear to be able to discriminate between groups. CPQ has been most widely tested and several versions are available. COHIP employed a rigorous development strategy but has been tested in fewer populations. C-OIDP is shorter and has been used successfully in epidemiological studies. Further testing using modern psychometric techniques such as item response theory is recommended. Future developments should also focus on the development of measures which can evaluate longitudinal change

Dental caries in primary and permanent teeth in children's worldwide, 1995 to 2019: a systematic review and meta-analysis

Background: Early childhood caries (ECC) is a type of dental caries in the teeth of infants and children that is represented as one of the most prevalent dental problems in this period. Various studies have reported different types of prevalence of dental caries in primary and permanent teeth in children worldwide. However, there has been no comprehensive study to summarize the results of these studies in general, so this study aimed to determine the prevalence of dental caries in primary and permanent teeth in children in different continents of the world during a systematic review and meta-analysis. Methods: In this review study, articles were extracted by searching in the national and international databases of SID, MagIran, IranMedex, IranDoc, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (ISI) between 1995 and December 2019. Random effects model was used for analysis and heterogeneity of studies was evaluated by using the I2 index. Data were analyzed by using the Comprehensive Meta-Analysis (Version 2) software. Findings: In this study, a total of 164 articles (81 articles on the prevalence of dental caries in primary teeth and 83 articles on the prevalence of dental caries in permanent teeth) were entered the meta-analysis. The prevalence of dental caries in primary teeth in children in the world with a sample size of 80,405 was 46.2% (95% CI: 41.6–50.8%), and the prevalence of dental caries in permanent teeth in children in the world with a sample size of 1,454,871 was 53.8% (95% CI: 50–57.5%). Regarding the heterogeneity on the basis of meta-regression analysis, there was a significant difference in the prevalence of dental caries in primary and permanent teeth in children in different continents of the world. With increasing the sample size and the year of study, dental caries in primary teeth increased and in permanent teeth decreased. Conclusion: The results of this study showed that the prevalence of primary and permanent dental caries in children in the world was found to be high. Therefore, appropriate strategies should be implemented to improve the aforementioned situation and to troubleshoot and monitor at all levels by providing feedback to hospitals

FORMATION OF THE PROFESSIONAL SCOPES DURING THE STUDY OF COURSE “TECHNOGENIC SYSTEMS AND ECOLOGICAL RISK”

This article examines matters relating to the formation of one of the key professional competencies for standard undergraduate specializations "ecology and management of natural resources"-knowledge of theoretical bases of ecological monitoring, regulation and reducing environmental pollution, man-made systems and environmental risk and the ability to use theoretical knowledge in practice. Study of the environmental aspects of the interaction of technological systems with the natural environment, the analysis of the environmental risks, study modern ways to ensure safe interaction of technological systems with the natural environment within the concept of sustainable development is an essential element of the mandate. The article presents issues that are necessary for the development of course content, structure and principles of selection of the contents, requirements to the level of preparation of students

The Correlation Between External and Internal Factors of the Libyan Crisis

Abstract: Nowadays, the region of Middle East and North Africa has become a "testing ground" where the competition between the great powers takes place . The importance of this region is determined by its geopolitical position, concentration of large natural resources, as well as the fact that it represents the greatest threat to the international security - the bases of terrorist organizations, the strengthening role of the group "Islamic State", drug trafficking and the proliferation of weapons of mass destruction (WMD). Socialist People's Libyan Arab Jamahiriya was one of the most developed and richest countries on the African continent: the crisis events of 2011, which resulted in the overthrow of the government, the murder of Muammar Gaddafi and the crisis in the country. From the viewpoint of the neoclassical realism the Libyan crisis is explored in the article. The causes of the crisis (both internal and external) as as well as the interests of the great powers - the United States of America, France and Britain are analyzed

Isolation and Characterization of Two Novel Siphoviruses Novomoskovsk and Bolokhovo, Encoding Polysaccharide Depolymerases Active against <em>Bacillus pumilus</em>

This study describes two novel bacteriophages infecting members of the Bacillus pumilus group. Even though members of the group are not recognized as pathogenic, several strains belonging to the group have been reported to cause infectious diseases in plants, animals and humans. Bacillus pumilus group species are highly resistant to ultraviolet radiation and capable of forming biofilms, which complicates their eradication. Bacteriophages Novomoskovsk and Bolokhovo were isolated from soil samples. Genome sequencing and phylogenetic analysis revealed that the phages represent two new species of the genus Andromedavirus (class Caudoviricetes). The phages remained stable in a wide range of temperatures and pH values. A host range test showed that the phages specifically infect various strains of B. pumilus. The phages form clear plaques surrounded by halos. Both phages Novomoskovsk and Bolokhovo encode proteins with pectin lyase domains—Putative depolymerases. Obtained in a purified recombinant form, the proteins produced lysis zones on the lawn of a B. pumilus strain. This suggests that Novomoskovsk and Bolokhovo may be effective for the eradication of B. pumilus biofilms