Impact of bioactive substances on the gastrointestinal tract and performance of weaned piglets: a review

The EU ban on in-feed antibiotics has stimulated research on weaning diets as a way of reducing post-weaning gut disorders and growth check in pigs. Many bioactive components have been investigated but only few have shown to be effective. Amongst these, organic acids (OA) have been shown to exert a bactericidal action mediated by non-dissociated OA, by lowering gastric pH, increasing gut and pancreas enzyme secretion and improving gut wall morphology. It has been postulated that they may also enhance non-specific immune responses and improve disease resistance. In contrast, relatively little attention has been paid to the impact of OA on the stomach but recent data show they can differently affect gastric histology, acid secretion and gastric emptying. Butyrate and precursors of butyric acid have received special attention and although promising results have been obtained, their effects are dependent upon the dose, treatment duration, initial age of piglets, gastrointestinal site and other factors. The amino acids (AA) like glutamine, tryptophan and arginine are supportive in improving digestion, absorption and retention of nutrients by affecting tissue anabolism, stress and (or) immunity. Glutamine, cysteine and threonine are important for maintaining mucin and permeability of intestinal barrier function. Spray-dried plasma (SDP) positively affects gut morphology, inflammation and reduces acquired specific immune responses via specific and a-specific influences of immunoglobulins and other bioactive components. Effects are more pronounced in early-weaned piglets and under poorer health conditions. Little interaction between plasma protein and antibiotics has been found, suggesting distinct modes of action and additive effects. Bovine colostrum may act more or less similarly to SDP The composition of essential oils is highly variable, depending on environmental and climatic conditions and distillation methods. These oils differ widely in their antimicrobial activity in vitro and some components of weaning diets may decrease their activity Results in young pigs are highly variable depending upon the product and doses used. These studies suggest that relatively high concentrations of essential oils are needed for beneficial effects to be observed and it has been assumed that these plant extracts mimic most of the effects of antibiotics active on gut physiology, microbiology and immunology. Often, bioactive substances protective to the gut also stimulate feed intake and growth performance. New insights on the effects of selected OA and AA, protein sources (especially SDP bovine colostrum) and plant extracts with anti-bacterial activities on the gut are reported in this review

Influence of laser-excited electron distributions on the x-ray magnetic circular dichroism spectra: Implications for femtosecond demagnetization in Ni

In pump-probe experiments an intensive laser pulse creates non-equilibrium excited electron distributions in the first few hundred femtoseconds after the pulse. The influence of non-equilibrium electron distributions caused by a pump laser on the apparent X-ray magnetic circular dichroism (XMCD) signal of Ni is investigated theoretically here for the first time, considering electron distributions immediately after the pulse as well as thermalized ones, that are not in equilibrium with the lattice or spin systems. The XMCD signal is shown not to be simply proportional to the spin momentum in these situations. The computed spectra are compared to recent pump-probe XMCD experiments on Ni. We find that the majority of experimentally observed features considered to be a proof of ultrafast spin momentum transfer to the lattice can alternatively be attributed to non-equilibrium electron distributions. Furthermore, we find the XMCD sum rules for the atomic spin and orbital magnetic moment to remain valid, even for the laser induced non-equilibrium electron distributions.Comment: 6 pages, 3 figure

Gravitational lensing statistics with extragalactic surveys. II. Analysis of the Jodrell Bank-VLA Astrometric Survey

We present constraints on the cosmological constant $\lambda_{0}$ from gravitational lensing statistics of the Jodrell Bank-VLA Astrometric Survey (JVAS). Although this is the largest gravitational lens survey which has been analysed, cosmological constraints are only comparable to those from optical surveys. This is due to the fact that the median source redshifts of JVAS are lower, which leads to both relatively fewer lenses in the survey and a weaker dependence on the cosmological parameters. Although more approximations have to be made than is the case for optical surveys, the consistency of the results with those from optical gravitational lens surveys and other cosmological tests indicate that this is not a major source of uncertainty in the results. However, joint constraints from a combination of radio and optical data are much tighter. Thus, a similar analysis of the much larger Cosmic Lens All-Sky Survey should provide even tighter constraints on the cosmological constant, especially when combined with data from optical lens surveys. At 95% confidence, our lower and upper limits on $\lambda_{0}-\Omega_{0}$, using the JVAS lensing statistics information alone, are respectively -2.69 and 0.68. For a flat universe, these correspond to lower and upper limits on \lambda_{0} of respectively -0.85 and 0.84. Using the combination of JVAS lensing statistics and lensing statistics from the literature as discussed in Quast & Helbig (Paper I) the corresponding $\lambda_{0}-\Omega_{0}$ values are -1.78 and 0.27. For a flat universe, these correspond to lower and upper limits on $\lambda_{0}$ of respectively -0.39 and 0.64.Comment: LaTeX, 9 pages, 18 PostScript files in 6 figures. Paper version available on request. Data available from http://gladia.astro.rug.nl:8000/ceres/data_from_papers/papers.htm

The QED Structure of the Photon

Measurements of the QED structure of the photon based on the reaction ee --> ee \gamma(*)(P^2)\gamma*(Q^2) --> ee mumu are discussed. This review is an update of the discussion of the results on the QED structure of the photon presented in Refs.[1], and covers the published measurements of the photon structure functions F_2, F_A nd F_B and of the differential cross-section dsig/dx for the exchange of two virtual photons.Comment: Invited talk given at the 7th International Workshop on Deep Inelastic Scattering and QCD, April 19 to 23, 1999, Zeuthen, to appear in the proceedings. 8pages 4 figure

Lensing galaxies: light or dark?

In a recent paper, Hawkins (1997) argues on the basis of statistical studies of double-image gravitational lenses and lens candidates that a large population of dark lenses exists and that these outnumber galaxies with more normal mass-to-light ratios by a factor of 3:1. If correct, this is a very important result for many areas of astronomy including galaxy formation and cosmology. In this paper we discuss our new radio-selected gravitational lens sample, JVAS/CLASS, in order to test and constrain this proposition. We have obtained ground-based and HST images of all multiple-image lens systems in our sample and in 12 cases out of 12 we find the lensing galaxies in the optical and/or near infrared. Our success in finding lensing galaxies creates problems for the dark lens hypothesis. If it is to survive, ad hoc modifications seem to be necessary: only very massive galaxies (more than about one trillion solar masses) can be dark, and the cutoff in mass must be sharp. Our finding of lens galaxies in all the JVAS/CLASS systems is complementary evidence which supports the conclusion of Kochanek et al. (1997) that many of the wide-separation optically-selected pairs are physically distinct quasars rather than gravitational lens systems.Comment: 4 pages, 2 included figures, accepted for publication in Astronomy and Astrophysics. Paper version available on request. This replacement amends the text to allow more discussion of the overlap with astro-ph/971016

The Hubble Constant from the Gravitational Lens B1608+656

We present a refined gravitational lens model of the four-image lens system B1608+656 based on new and improved observational constraints: (i) the three independent time-delays and flux-ratios from VLA observations, (ii) the radio-image positions from VLBA observations, (iii) the shape of the deconvolved Einstein Ring from optical and infrared HST images, (iv) the extinction-corrected lens-galaxy centroids and structural parameters, and (v) a stellar velocity dispersion, sigma_ap=247+-35 km/s, of the primary lens galaxy (G1), obtained from an echelle spectrum taken with the Keck--II telescope. The lens mass model consists of two elliptical mass distributions with power-law density profiles and an external shear, totaling 22 free parameters, including the density slopes which are the key parameters to determine the value of H_0 from lens time delays. This has required the development of a new lens code that is highly optimized for speed. The minimum-chi^2 model reproduces all observations very well, including the stellar velocity dispersion and the shape of the Einstein Ring. A combined gravitational-lens and stellar dynamical analysis leads to a value of the Hubble Constant of H_0=75(+7/-6) km/s/Mpc (68 percent CL; Omega_m=0.3, Omega_Lambda=0.7. The non-linear error analysis includes correlations between all free parameters, in particular the density slopes of G1 and G2, yielding an accurate determination of the random error on H_0. The lens galaxy G1 is ~5 times more massive than the secondary lens galaxy (G2), and has a mass density slope of gamma_G1=2.03(+0.14/-0.14) +- 0.03 (68 percent CL) for rho~r^-gamma', very close to isothermal (gamma'=2). (Abridged)Comment: 17 pages, 6 figures, 5 tables; revised version with correct fig.6 and clarified text based on referee report; conclusions unchange

The remittances behaviour of the second generation in Europe: altruism or self-interest?

Whereas most research on remittances focuses on first-generation migrants, the aim of this paper is to investigate the remitting behaviour of the host country-born children of migrants - the second generation - in various European cities. Some important studies found that migrant transnationalism is not only a phenomenon for the first generation, but also apply to the second and higher generations, through, among other things, family visits, elder care, and remittances. At the same time, the maintenance of a strong ethnic identity in the ‘host’ society does not necessarily mean that second-generation migrants have strong transnational ties to their ‘home’ country. The data used in this paper is from “The Integration of the European Second Generation” (TIES) project. The survey collected information on approximately 6,250 individuals aged 18-35 with at least one migrant parent from Morocco, Turkey or former Yugoslavia, in 15 European cities, regrouped in 8 ‘countries’. For the purpose of this paper, only analyses for Austria (Linz and Vienna); Switzerland (Basle and Zurich); Germany (Berlin and Frankfurt); France (Paris and Strasbourg); the Netherlands (Amsterdam and Rotterdam); Spain (Barcelona and Madrid); and Sweden (Stockholm) will be presented.