Epidemiology and mortality of burns at the Queen Elizabeth Central Hospital Blantyre, Malawi

A CAJM journal article.Objectives: To determine the most common causes, population most at risk and the pattern of mortality of burn injuries at the Queen Elizabeth Central Hospital, Blantyre,Malawi’ Design: Retrospective cross sectional study. Setting: Burns Unit, Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi

Sexually transmitted diseases at Queen Elizabeth Central Hospital, Blantyre, Malawi

Objectives: To re-assess attendance at the sexually transmitted diseases (STDs) clinic in relation to age, sex and seasonal variation over a three-year period, and to determine the pattern of STD syndromes presenting at the STDs clinic, Queen Elizabeth Central Hospital, Blantyre, Malawi.Design: A retrospective study.Setting: STDs clinic, Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi.Results: The study findings indicate that of the 50,524 attendees, 52.72% and 47.28% were males and females respectively. Over the period there was a significant (30.7%) increase in the number of attendees from 14,622 (28.94%) in 1996 and 16,794 (33.24%) in 1997 to 19,008 (37.82%) in 1998, a trend that was also observed among the sexes. The age range was between 11 and 72 years. More than half(53.55%) of the patients were within 21 to 30 years age rangewhile a total of 48,054 (95.11%) were below 50 years. The most frequently presented STDs syndromes among the 21- 30 year age group were genital ulcer disease (GUD) (40.86%), genitourinary symptoms high risk (GUS - HR) (20.46%), urethral discharge (UD) (15.65%) and pelvic inflammatory diseases (PID) (13.37%). The four constituted 90.34% of all case presentations. Balanitis (BA) was the least common at 0.32% or 86 cases in three years. Whilethe incidence of genitourinary symptoms low risk (GUS - LR) decreased over the years and no clear pattern could be established with (GUS - HR), acute scrotal swelling/pain (SS), and BA, numerical increase in the presentation of UD, PID and enlarged inguinal lymph nodes(BU) was observed. However, the phenomenal increase in the prevalence of STDs particularly GUD rising from 2,988 (37.70%) in 1996 and 3,674 (40.27%) in 1997 to 4,392 (43.88%) in 1998 respectively was noted with concern. There seemed to be a link between seasonal variation and attendance at the STD clinic as more cases presented between March and May peaking in April of each year while December period recorded the least attendance.Conclusion: Attendance rate at the STDs clinic, Queen Elizabeth Central Hospital, Blantyre, is still on the increase in spite of the various STDs/HIV/AIDS awareness campaign programmes

The synergism of hepatitis B and aflatoxicosis in hepatocellular carcinoma development: A mini-review

Hepatocellular carcinoma (HCC) is the twelfth most common cancer and the fifth leading cause of worldwide cancer-related death. Chronic hepatitis B infection, caused by the hepatitis B virus (HBV) and exposure to aflatoxins is fundamental in the formation of HCC in developing countries. This review of scientific publications aims to establish the detrimental effects of aflatoxin-contaminated foods and highlights the correlation between aflatoxin and hepatitis B viral-associated hepatocellular carcinoma. Research has shown a significant increase in the occurrence of HCC in HBV-infected individuals exposed to fungal toxins. HBV demonstrates the ability to integrate and bind to p53 protein in the host DNA and propagate hepatocyte vulnerability through carcinogenic aflatoxin B1 (AFB1) damage. Although there has been clear evidence about the synergistic interaction of exposure to AFB1 and HBV infection in the induction of HCC, other literature has shown otherwise, mainly because incomplete and vague findings and hypotheses were made in regions where AFB1 and HBV pose a public health risk. Vaccination against hepatitis B and measures such as robust food safety systems to avoid hepatotoxicity and hepatocellular carcinogenesis induced by AFB1 is the most effective methods in the prevention of HCC induced by HBV and AFB

Small Ruminant Farmers' Perception of Climate Change in Moro Local Government Area, Kwara State, Nigeria

This study examined the small ruminant farmers’ perception of climate change in Moro Local Government Area (LGA) of Kwara State, Nigeria. About 120 small ruminant farmers were selected for the study. Analyticall tools such as descriptive (frequency count, percentage, mean score) and inferential [Pearson product moment correlation (PPMC)] statistics were used to analyse the data. The result revealed that about 57.5% of the respondents were male, average age of 38.3years, income of N56633.33, and household size of about 5 persons. The average number of goat and sheep was 10 and 5 respectively. About 52% of the respondents utilized extensive system of rearing and 60.8% had access to extension services. About 77.5% of the respondents indicated Ministry of Agriculture as their main source of information on small ruminant production. The result revealed that planting of trees/erecting cover to serve as shades to reduce heat stress (90.8%) was the most frequently used adaptation strategies to climate change. About 59.2% of the respondents have high level/status of use of adaptation strategies. The highest ranked perception statement was increase in temperature (4.48), while disease outbreak and high mortality (2.78) ranked highest as factor affecting small ruminant production. It is therefore recommended that there should be provision of information on the adaptation strategies as climate change is now a reality that is not going away and provision of veterinary services to reduce disease outbreak

A quantitative structure-biodegradation relationship (QSBR) approach to predict biodegradation rates of aromatic chemicals

The objective of this work was to develop a QSBR model for the prioritization of organic pollutants based on biodegradation rates from a database containing globally harmonized biodegradation tests using relevant molecular descriptors. To do this, we first categorized the chemicals into three groups (Group 1: simple aromatic chemicals with a single ring, Group 2: aromatic chemicals with multiple rings and Group3: Group 1 plus Group 2) based on molecular descriptors, estimated the first order biodegradation rate of the chemicals using rating values derived from the BIOWIN3 model, and finally developed, validated and defined the applicability domain of models for each group using a multiple linear regression approach. All the developed QSBR models complied with OECD principles for QSAR validation. The biodegradation rate in the models for the two groups (Group 2 and 3 chemicals) are associated with abstract molecular descriptors that provide little relevant practical information towards understanding the relationship between chemical structure and biodegradation rates. However, molecular descriptors associated with the QSBR model for Group 1 chemicals (R2 = 0.89, Q2loo = 0.87) provided information on properties that can readily be scrutinised and interpreted in relation to biodegradation processes. In combination, these results lead to the conclusion that QSBRs can be an alternative tool to estimate the persistence of chemicals, some of which can provide further insights into those factors affecting biodegradation

Implications of Deceptive Practices of Poultry Input Suppliers on Poultry Production in Kwara State, Nigeria

Deceptive practices of poultry input suppliers are partly responsible for inability to meet the consumption of recommended animal protein (35g/person/day). The study examined the prevailing deceptive practices and effects on poultry production in Nigeria. Proportionate random sampling technique was used to select 70 small scale poultry farmers used as respondents. Data were analyzed using percentages and means. The respondents (68.6%) had a minimum of secondary school education and spent averagely 15.7 years in poultry production. The findings showed that deceptive practices include adulteration of feed ingredients, marketing of under‑weighed feeds, lack of proximate analysis of nutrient composition of feeds and use of old bags for packaging. The respondents (81.3%) agreed that deceptive practices delayed the start of growing period of the fowls. Similarly, 79.5% and 61% experienced low meat and egg production, respectively, resulting in expensive animal protein, increased production overheads (83.4%), lowered returns on investment (90.1%). The result of hypothesis indicated a positive significant relationship between the level of educational attainment of respondents and ability to identify deceptive practices in poultry production (R = 0.214, P ≤ 0.05) among respondents. Nigerian Institute of Animal Science and other relevant regulatory agencies should have a structure to regulate and award penalties to culpable individuals in these deceptive practices. Extension organizations should educate poultry producers on the concept of deceptive practices and its consequences. Keywords: adulteration; poultry feeds; egg production; poultry meat production

Determinants of first‐ever stroke severity in West Africans: evidence from the SIREN study

Background: Baseline stroke severity is probably partly responsible for poor stroke outcomes in sub-Saharan Africa. However, there is a paucity of information on determinants of stroke severity among indigenous Africans. We sought to identify the factors associated with stroke severity among West Africans in the SIREN (Stroke Investigative Research and Educational Networks) study. Methods and Results: Stroke was diagnosed clinically and confirmed with brain neuroimaging. Severe stroke was defined as a Stroke Levity Scale score of ≤5. A multivariate logistic regression model was constructed to identify factors associated with stroke severity at 95% CI and a nominal cutoff of 5% type 1 error. A total of 3660 stroke cases were included. Overall, 50.7%% had severe stroke, including 47.6% of all ischemic strokes and 56.1% of intracerebral hemorrhage. Factors independently associated with severe stroke were meat consumption (adjusted odds ratio [aOR], 1.97 [95% CI, 1.43-2.73]), low vegetable consumption (aOR, 2.45 [95% CI, 1.93-3.12]), and lesion volume, with an aOR of 1.67 (95% CI, 1.03-2.72) for lesion volume of 10 to 30 cm3 and aOR of 3.88 (95% CI, 1.93-7.81) for lesion volume \u3e30 cm3. Severe ischemic stroke was independently associated with total anterior circulation infarction (aOR, 3.1 [95% CI, 1.5-6.9]), posterior circulation infarction (aOR, 2.2 [95% CI, 1.1-4.2]), and partial anterior circulation infarction (aOR, 2.0 [95% CI, 1.2-3.3]) compared with lacunar stroke. Increasing age (aOR, 2.6 [95% CI, 1.3-5.2]) and lesion volume \u3e30 cm3 (aOR, 6.2 [95% CI, 2.0-19.3]) were independently associated with severe intracerebral hemorrhage. Conclusions: Severe stroke is common among indigenous West Africans, where modifiable dietary factors are independently associated with it. These factors could be targeted to reduce the burden of severe stroke

An automated process for inclusion of package dies and circuitry within a textile yarn

The integration of small electronic components into textile fabrics, without compromising the textile qualities such as flexibility and conformability, is necessary in ensuring wider adoption of electronic textiles. A solution is to use flexible, electronic yarns that incorporate electronic components within the fibers of the yarn. The production of these novel yarns was initially a craft skill, with inclusion of electronics within each section of yarn taking 60–90 minutes. A prototype, automated production process was developed to speed up the manufacturing process to 6 minutes. This paper describes the process, using machinery and methods from both electronics and textiles applications

Design and Fabrication of an Okra Threshing Machine

A simple Okra threshing machine was designed, fabricated and tested to alleviate the problems associated with Okra processing in Nigeria. It is consists mainly of five units namely, the feeding assembly, the threshing unit, separation unit, power transmission unit. The overall mean threshing and cleaning efficiencies obtained were 93.95 and 99.56% respectively. Drum speed 500rpm combine with 55mm concave clearance gave the highest Threshing efficiency of 99.99%. All speeds, concave clearance combinations gave clearing efficiency above 98%. The machine threshing and cleaning efficiencies increased with increase in drum speed and decrease with increase in concave clearance. The machine is simple to operate and maintain without formal training

Wash testing of electronic yarn

Electronically active yarn (E-yarn) pioneered by the Advanced Textiles Research Group of Nottingham Trent University contains a fine conductive copper wire soldered onto a package die, micro-electro-mechanical systems device or flexible circuit. The die or circuit is then held within a protective polymer packaging (micro-pod) and the ensemble is inserted into a textile sheath, forming a flexible yarn with electronic functionality such as sensing or illumination. It is vital to be able to wash E-yarns, so that the textiles into which they are incorporated can be treated as normal consumer products. The wash durability of E-yarns is summarized in this publication. Wash tests followed a modified version of BS EN ISO 6330:2012 procedure 4N. It was observed that E-yarns containing only a fine multi-strand copper wire survived 25 cycles of machine washing and line drying; and between 5 and 15 cycles of machine washing followed by tumble-drying. Four out of five temperature sensing E-yarns (crafted with thermistors) and single pairs of LEDs within E-yarns functioned correctly after 25 cycles of machine washing and line drying. E-yarns that required larger micro-pods (i.e., 4 mm diameter or 9 mm length) were less resilient to washing. Only one out of five acoustic sensing E-yarns (4 mm diameter micro-pod) operated correctly after 20 cycles of washing with either line drying or tumble-drying. Creating an E-yarn with an embedded flexible circuit populated with components also required a relatively large micro-pod (diameter 0.93 mm, length 9.23 mm). Only one embedded circuit functioned after 25 cycles of washing and line drying. The tests showed that E-yarns are suitable for inclusion in textiles that require washing, with some limitations when larger micro-pods were used. Reduction in the circuit’s size and therefore the size of the micro-pod, may increase wash resilience