241 research outputs found

    Managing global expansion of media products and brands: A case study of FHM

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    By focusing on the case study of For Him Magazine (FHM)—a magazine that currently sells in 30 editions across 5 continents—this article explores the economics and main managerial challenges associated with global expansion of media products. The success of FHM demonstrates that, to calculate the full returns available from the brand image created by a magazine title, publishers will take into account not only opportunities for domestic and international exploitation of the magazine, but also the potential to extend the brand across additional media platforms and additional complementary product markets. This study focuses on how global expansion of FHM has been managed

    Decarbonising heating and cooling using temperature setback and geothermal energy

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    \ua9 2023 Institute of Physics Publishing. All rights reserved. The lion’s share of buildings’ energy consumption is used for maintaining a thermally comfortable indoor environment. Strategies of reducing heating and cooling demand can thus be crucial for buildings to achieve net zero. This research aims to investigate the extent to which an occupancy-based temperature setback strategy and geothermal energy supply can decarbonise an office building. The objectives include: 1) exploring the optimal setback temperature for maximum energy savings, both in present time and under the future climate scenarios, and 2) evaluating the extent to which a geothermal borehole can meet the building’s energy demand. The outcome shows that a temperature setback strategy coupled with geothermal energy supply can decarbonise heating and cooling by around half. As for overall building energy demand, temperature setback can make demand reduction by over a tenth while the geothermal energy can meet the demand by a minimum of a fifth

    Acromioplasty during repair of rotator cuff tears removes only half of the impinging acromial bone.

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    To date, there is no consensus on when and how to perform acromioplasty during rotator cuff repair (RCR). We aimed to determine the volume of impinging bone removed during acromioplasty and whether it influences postoperative range of motion (ROM) and clinical scores after RCR. Preoperative and postoperative computed tomography scans of 57 shoulders that underwent RCR were used to reconstruct scapula models to simulate volumes of impinging acromial bone preoperatively and then compare them to the volumes of bone resected postoperatively to calculate the proportions of desired (ideal) vs. unnecessary (excess) resections. All patients were evaluated preoperatively and at 6 months to assess ROM and functional scores. The volume of impinging bone identified was 3.5 ± 2.3 cm <sup>3</sup> , of which 1.6 ± 1.2 cm <sup>3</sup> (50% ± 27%) was removed during acromioplasty. The volume of impinging bone identified was not correlated with preoperative critical shoulder angle (r = 0.025, P = .853), nor with glenoid inclination (r = -0.024, P = .857). The volume of bone removed was 3.7 ± 2.2 cm <sup>3</sup> , of which 2.1 ± 1.6 cm <sup>3</sup> (53% ± 24%) were unnecessary resections. Multivariable analyses revealed that more extensive removal of impinging bone significantly improved internal rotation with the arm at 90° of abduction (beta, 27.5, P = .048) but did not affect other shoulder movements or clinical scores. Acromioplasty removed only 50% of the estimated volume of impinging acromial bone. More extensive removal of impinging bone significantly improved internal rotation with the arm at 90° of abduction

    Adaptive isogeometric analysis for phase‐field modeling of anisotropic brittle fracture

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    The surface energy a phase‐field approach to brittle fracture in anisotropic materials is also anisotropic and gives rise to second‐order gradients in the phase field entering the energy functional. This necessitates C 1 continuity of the basis functions which are used to interpolate the phase field. The basis functions which are employed in isogeometric analysis (IGA), such as nonuniform rational B‐splines and T‐splines naturally possess a higher order continuity and are therefore ideally suited for phase‐field models which are equipped with an anisotropic surface energy. Moreover, the high accuracy of spline discretizations, also relative to their computational demand, significantly reduces the fineness of the required discretization. This holds a fortiori if adaptivity is included. Herein, we present two adaptive refinement schemes in IGA, namely, adaptive local refinement and adaptive hierarchical refinement, for phase‐field simulations of anisotropic brittle fracture. The refinement is carried out using a subdivision operator and exploits the Bézier extraction operator. Illustrative examples are included, which show that the method can simulate highly complex crack patterns such as zigzag crack propagation. An excellent agreement is obtained between the solutions from global refinement and adaptive refinement, with a reasonable reduction of the computational effort when using adaptivity

    Scrub typhus ecology: a systematic review of Orientia in vectors and hosts

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    Abstract Scrub typhus, caused by Orientia tsutsugamushi, is an important and neglected vector-borne zoonotic disease with an expanding known distribution. The ecology of the disease is complex and poorly understood, impairing discussion of public health interventions. To highlight what we know and the themes of our ignorance, we conducted a systematic review of all studies investigating the pathogen in vectors and non-human hosts. A total of 276 articles in 7 languages were included, with 793 study sites across 30 countries. There was no time restriction for article inclusion, with the oldest published in 1924. Seventy-six potential vector species and 234 vertebrate host species were tested, accounting for over one million trombiculid mites (‘chiggers’) and 83,000 vertebrates. The proportion of O. tsutsugamushi positivity was recorded for different categories of laboratory test and host species. Vector and host collection sites were geocoded and mapped. Ecological data associated with these sites were summarised. A further 145 articles encompassing general themes of scrub typhus ecology were reviewed. These topics range from the life-cycle to transmission, habitats, seasonality and human risks. Important gaps in our understanding are highlighted together with possible tools to begin to unravel these. Many of the data reported are highly variable and inconsistent and minimum data reporting standards are proposed. With more recent reports of human Orientia sp. infection in the Middle East and South America and enormous advances in research technology over recent decades, this comprehensive review provides a detailed summary of work investigating this pathogen in vectors and non-human hosts and updates current understanding of the complex ecology of scrub typhus. A better understanding of scrub typhus ecology has important relevance to ongoing research into improving diagnostics, developing vaccines and identifying useful public health interventions to reduce the burden of the disease.</jats:p

    Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

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    Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining https://researchonline.ljmu.ac.uk/images/research_banner_face_lab_290.jpgunderweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity

    Step by step. Erfolgsfaktoren wissensbasierter Unternehmensnetze

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    Die Vernetzung von Wissensressourcen wird für Unternehmen ein entscheidender Erfolgsfaktor des modernen Managements, denn Wissen gewinnt als immaterieller Produktionsfaktor zunehmend an Bedeutung. Folgerichtiges und stufenweises Vorgehen beim Aufbau wissenbasierter Unternehmensnetze sind dabei besonders wichtig für Akzeptanz und Nachhaltigkeit

    Visionen zur Mediennutzung im privaten Sektor - Potentiale und Hemmschwellen

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    Based on a survey among experts to the future use of media in the private sector statements on two time horizons (2005 and 2015) will be made. These statements concern: the significance of different personal or private needs, the aspects of hard-/software-design that are important for user-acceptance, the signicance of the context in which usage takes place as well as the competences of the users, the importance that is attached to user benefits when comparing new and tranditional media. The share of new media products and services will be predicted. Furthermore the time scale as the dissemination of new products and services will be assessed
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