43 research outputs found

    Print or Perish? Authors’ Attitudes Toward Electronic-Only Publication of Law Journals

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    An increasing number of U.S. law journals post at least current issues in freely accessible PDF and (in some cases) HTML formats on their web sites. Yet, perhaps without exception, the journals that make their articles freely available on their websites also continue to publish print issues in the face of declining subscription numbers, and law libraries\u27 growing disinterest in collecting and preserving journals in print. As universities reduce staff, freeze open positions, eliminate salary increases, and cut library budgets, why have law schools continued to subsidize print publication of journals that are accessible in electronic formats? Among the reasons suggested for this is the possible impact on a journals reputation and ability to attract authors if it moved to electronic-only publication. This paper reports on the results of a survey of law journal authors\u27 attitudes toward electronic-only law journals

    Electoral fraud is less common in proportional representation systems than it is in plurality systems

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    What impact does the electoral system in use have on levels of electoral quality and fraud? Fabrice Lehoucq and Kiril Kolev share research which shows that plurality electoral systems lead to more ballot rigging than do proportional systems, that plurality systems are associated with inferior election quality in the Quality of Elections Database, and that electoral formulae have as much impact as social structure on whether elections are free and fair

    Applications of Monte Carlo Simulation in Modelling of Biochemical Processes

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    The biochemical models describing complex and dynamic metabolic systems are typically multi-parametric and non-linear, thus the identification of their parameters requires nonlinear regression analysis of the experimental data. The stochastic nature of the experimental samples poses the necessity to estimate not only the values fitting best to the model, but also the distribution of the parameters, and to test statistical hypotheses about the values of these parameters. In such situations the application of analytical models for parameter distributions is totally inappropriate because their assumptions are not applicable for intrinsically non-linear regressions. That is why, Monte Carlo simulations are a powerful tool to model biochemical processes

    Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin

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    Background Removal of C-terminal lysine residues that are continuously exposed in lysing fibrin is an established anti-fibrinolytic mechanism dependent on the plasma carboxypeptidase TAFIa, which also removes arginines that are exposed at the time of fibrinogen clotting by thrombin. Objective To evaluate the impact of alterations in fibrin structure mediated by constitutive carboxypeptidase activity on the function of fibrin as a template for tissue plasminogen activator-(tPA) induced plasminogen activation and its susceptibility to digestion by plasmin. Methods and results We used the stable carboxypeptidase B (CPB), which shows the same substrate specificity as TAFIa. If 1.5 – 6 μM fibrinogen was clotted in the presence of 8 U/mL CPB, a denser fibrin network was formed with thinner fibers (the median fiber diameter decreased from 138 – 144 nm to 89 – 109 nm as established with scanning electron microscopy). If clotting was initiated in the presence of 5 – 10 μM arginine, a similar decrease in fiber diameter (82 -95 nm) was measured. The fine structure of arginine-treated fibrin enhanced plasminogen activation by tPA, but slowed down lysis monitored using fluorescent tPA and confocal laser microscopy. However, if lysis was initiated with plasmin in CPB-treated fibrin, the rate of dissolution increased to a degree corresponding to doubling of the plasmin concentration. Conclusion The present data evidence that CPB activity generates fine-mesh fibrin which is more difficult to lyse by tPA, but conversely, CPB and plasmin together can stimulate fibrinolysis, possibly by enhancing plasmin diffusion

    The Contingent Effect of Institutions: Ethno-Cultural Polarization, Electoral Formulas and Election Quality

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    <p>Less democratic countries conduct elections under the majoritarian electoral formula more often than under proportional representation by a wide margin. Yet, robust democratic systems utilize both majoritarian and PR electoral formulas with great success. This dissertation approaches this empirical puzzle and tries to unveil what role, if any, electoral formulas play in politics.</p><p> To do so, it focuses on the electoral process exclusively and utilizes Judith Kelley's recently completed comprehensive dataset on election quality to perform some large-sample statistical analyses of the relationship between the electoral formula, ethno-cultural polarization and election quality. Then, it presents three in-depth case studies of Nigeria, Ghana and Indonesia to unveil in more detail institutional origins and the mechanisms of electoral manipulation, as refracted through the electoral formula. </p><p>The conclusions reached are that PR is much better suited for conducting free and fair elections in ethno-culturally polarized countries. Yet, majoritarian and mixed formulas perform just as well when polarization is low. This finding is directly related to an ongoing debate by institutional designers and academics alike and provides systematic quantitative and detailed qualitative support. The study also suggests that PR might not only mediate inter-ethnic differences when disagreement is high, but also reduces the level of polarization if applied over several electoral cycles.</p>Dissertatio

    Replication Data for: Ethnic Group Inequality, Partisan Networks and Political Clientelism

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    How do ethnic group divisions affect parties' linkage strategies? The provision of private or local club goods favoring co-ethnics by politicians has been well documented in the literature. However, whether clientelism tends to be more widespread in ethnically highly fragmented societies has not been systematically examined. Utilizing a dataset that includes information on more than 450 parties in 80 competitive party systems, we show that the mere presence of multiple ethnic groups does not lead to more clientelistic exchange. Nevertheless, in countries characterized by high levels of economic inequality between politically relevant ethnic groups, parties are more likely to rely on clientelistic strategies to attract votes. In addition, this positive relationship between ethnic income inequality and clientelism is contingent on parties' ties to ethnic social networks. Specifically, in ethnically unequal societies, parties that can rely on existing ethnic organizations particularly engage in clientelistic mode of electoral mobilization
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