Evolution of ecological specialization and venom of a predatory marine gastropod

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74591/1/j.1365-294X.2007.03627.x.pd

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer.

Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance (neor). The infected cells were infused back into the lethally irradiated donor animals. Several monkeys fully reconstituted and were shown to express the h-ADA and neor genes at low levels in their recirculating hematopoietic cells for short periods of time

Depicting combinatorial complexity with the molecular interaction map notation

To help us understand how bioregulatory networks operate, we need a standard notation for diagrams analogous to electronic circuit diagrams. Such diagrams must surmount the difficulties posed by complex patterns of protein modifications and multiprotein complexes. To meet that challenge, we have designed the molecular interaction map (MIM) notation (http://discover.nci.nih.gov/mim/). Here we show the advantages of the MIM notation for three important types of diagrams: (1) explicit diagrams that define specific pathway models for computer simulation; (2) heuristic maps that organize the available information about molecular interactions and encompass the possible processes or pathways; and (3) diagrams of combinatorially complex models. We focus on signaling from the epidermal growth factor receptor family (EGFR, ErbB), a network that reflects the major challenges of representing in a compact manner the combinatorial complexity of multimolecular complexes. By comparing MIMs with other diagrams of this network that have recently been published, we show the utility of the MIM notation. These comparisons may help cell and systems biologists adopt a graphical language that is unambiguous and generally understood

Use of Repeated Within-Subject Measures to Assess Infants’ Preference for Similar Others

Research employing single-choice paradigms in which an infant is asked to make a single choice between two puppets suggest that infants show a preference for prosocial others and those who are similar to themselves. However, the extent to which infants’ preference for similar others is stable is unknown, as are other factors within the paradigm that may influence infants’ choices. The purpose of this study (two experiments, N = 44 infants, aged 8–15 months) was to replicate and extend previous work by including (1) within-subject repeated measures and (2) an experimental manipulation of a plausible demand characteristic. Results for the first-choice trial indicated a majority of the infants did not choose the similar puppet. Results from the within-subject repeated trials also indicated that a majority of the infants did not choose the similar puppet but a majority did choose a puppet from the same side. The experimental manipulation of the demand characteristic showed no effect on infant puppet choices. These results suggest that a closer examination of the single-choice puppet paradigm for assessing infants’ social evaluation is warranted. These findings also support recommendations made by others, including publishing null findings, standardizing data collection and reporting methods, and examining individual differences by employing within-subject designs with repeated measures

Density functional theory calculations on magnetic properties of actinide compounds

We have performed a detailed analysis of the magnetic (collinear and noncollinear) order and atomic and the electron structures of UO2, PuO2 and UN on the basis of density functional theory with the Hubbard electron correlation correction (DFT+U). We have shown that the 3-k magnetic structure of UO2 is the lowest in energy for the Hubbard parameter value of U=4.6 eV (and J=0.5 eV) consistent with experiments when Dudarev's formalism is used. In contrast to UO2, UN and PuO2 show no trend for a distortion towards rhombohedral structure and, thus, no complex 3-k magnetic structure is to be anticipated in these materials.Comment: 5 pages, 3 figures 1 table, submitted to Phys. Chem. Chem. Phy

The Ursinus Weekly, March 1, 1965

Junior class extends invitation to Carousel: Al Raymond band at Sunnybrook • Pi Nu Epsilon sponsors annual Greek song fest • Students and faculty contribute to art show: Prizes awarded to varied entries in 3 day exhibit • Spring Festival adopts South Pacific theme, selects committees • WSGA plans to adopt a child • Students to dramatize un-American hearing • Collegeville coffee house provides weekend activity • Whitians greet scholastic women in biannual tea • Rushing, or - a puzzled frosh asks Why am I so popular? • Baseball season starts tomorrow • Editorial: Cheating • Frosh to receive colors in annual ceremony • Letters to the editor • Customs: Its development and its demise • Bears end week 1 for 2; Finish season 8-9: Troster and Parker standouts • Ursinus splits two games; Beats Beaver, loses to W.C. • Ursinus matmen lose two; Swath. & Drexel are close • Badminton team • Year in review • Advice columnhttps://digitalcommons.ursinus.edu/weekly/1241/thumbnail.jp

Variation and evolution of toxin gene expression patterns of six closely related venomous marine snails

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75661/1/j.1365-294X.2008.03804.x.pd

Broadband laser cooling of trapped atoms with ultrafast pulses

We demonstrate broadband laser cooling of atomic ions in an rf trap using ultrafast pulses from a modelocked laser. The temperature of a single ion is measured by observing the size of a time-averaged image of the ion in the known harmonic trap potential. While the lowest observed temperature was only about 1 K, this method efficiently cools very hot atoms and can sufficiently localize trapped atoms to produce near diffraction-limited atomic images