27 research outputs found

    In Vivo Imaging Reveals Dendritic Targeting of Laminated Afferents by Zebrafish Retinal Ganglion Cells

    Get PDF
    SummaryTargeting of axons and dendrites to particular synaptic laminae is an important mechanism by which precise patterns of neuronal connectivity are established. Although axons target specific laminae during development, dendritic lamination has been thought to occur largely by pruning of inappropriately placed arbors. We discovered by in vivo time-lapse imaging that retinal ganglion cell (RGC) dendrites in zebrafish show growth patterns implicating dendritic targeting as a mechanism for contacting appropriate synaptic partners. Populations of RGCs labeled in transgenic animals establish distinct dendritic strata sequentially, predominantly from the inner to outer retina. Imaging individual cells over successive days confirmed that multistratified RGCs generate strata sequentially, each arbor elaborating within a specific lamina. Simultaneous imaging of RGCs and subpopulations of presynaptic amacrine interneurons revealed that RGC dendrites appear to target amacrine plexuses that had already laminated. Dendritic targeting of prepatterned afferents may thus be a novel mechanism for establishing proper synaptic connectivity

    STEPP NVivo file

    No full text
    This is the NVivo file for our article, "A Qualitative Content Analysis of Whitelists vs Blacklists: How do they address the issue of predatory publishing?

    Activism by Accuracy: Women\u27s Health and Hormonal Birth Control

    No full text
    By juxtaposing contemporary hormonal birth control advertisements with naturopathic discourses about women’s hormones, this chapter argues that accurate information about hormonal birth control from alternative practitioners is a powerful form of activism—activism by accuracy. This chapter also explores how alternative and naturopathic discourses provide powerful counter-narratives to existing doxastic beliefs about hormonal birth control by providing patients with accurate hormonal and physiological health information. Furthermore, examining doxa that exist beneath the surface of current medical discourses on hormonal birth control (e.g., prioritizing effectiveness to prevent pregnancy over hormonal health) exposes how doxa persist and the rhetorical work they accomplish

    The Predatory Paradox

    Get PDF
    La vie universitaire ressemble beaucoup à une émission de téléréalité. Dans à la fois la télévision de réalité et la production de connaissances académiques, nous avons ceux qui participent au processus (candidats et chercheurs), nous avons ceux qui profitent du processus (producteurs et éditeurs), et nous avons des consommateurs (téléspectateurs et lecteurs). Bref, la téléréalité expose tout le désordre, la beauté, la complexité, l’élégance et laideur inhérente à toute entreprise qui implique plusieurs humains. La vie académique ne fait pas exception
    corecore