329 research outputs found
Fast cooling following a Late Triassic metamorphic and magmatic pulse: implications for the tectonic evolution of the Korean collision belt
International audienceWe discuss the evolution of Korea in the context of a relatively short-lived, tectonically induced, magmatic and metamorphic pulse that affected large portions of the crust of the peninsula's southern part during the Late Triassic. Recent 40Ar/39Ar single grain laser step-heating dates imply a prolonged metamorphic recrystallization between 243 and 220 Ma, which occurred in distinct phases that were not coeval throughout the peninsula. We obtained identical plateau ages between 231.4 ± 0.8 and 228.9 ± 0.8 Ma (1σ; 85–95% 39Ar release) on single grains of detrital muscovite from Jurassic sandstones (Gimpo Group). A literature review shows that the ages of detrital muscovites are identical to: (1) concordant 40Ar/39Ar ages of biotite (228 Ma) and amphibole (230 Ma) in amphibolites of the Deokjeongri Gneiss Formation and the Weolhyeonri Complex, pointing to very rapid cooling of 100–150 °C/Ma, and (2) 231–229 Ma muscovite from the low-grade metamorphic mid-Paleozoic turbidites of the Taean Formation. The efficiency of cooling is further underlined by the near-coincidence of these 40Ar/39Ar ages with 243–229 Ma (average: 234.6 Ma) zircon U–Pb ages in the Gyeonggi Massif and the Hongseong belt, in the literature. It is argued that the Late Triassic magmatic and metamorphic pulse is superimposed on an earlier tectono-metamorphic event, possibly related to collision, indicated by: (1) ~ 243–237 Ma muscovite ages, or age components in age spectra, and (2) two generations of folds and associated tectonic foliations truncated by ~ 229.5-Ma-old syenites and earlier mafic dykes. The Late Triassic thermal pulse could have been the result of post-collisional delamination of the lower crust and uppermost mantle, and/or oceanic slab break-off, which is also suggested by almost coeval, widespread mantle-sourced Mg-rich potassic magmatism. Continuing ductile deformation is shown by mylonitization of Late Triassic magmatic rocks; an ~ 220 Ma muscovite age may be related to this
Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
Although little is known on the true prevalence of pancreatic cysts, physicians are currently more frequently confronted with pancreatic cysts because of the increasing use of sophisticated cross-sectional abdominal imaging. Cystic lesions of the pancreas comprise of a heterogeneous group of diagnostic entities, some of which are benign such as inflammatory pseudocysts or serous cystadenomas and do not require resection when asymptomatic. Others like mucinous cysts or intraductal papillary mucinous neoplasms (IPMN) have a malignant potential and in these cases surgical resection is often indicated. For this reason an adequate distinction between the various cysts is crucial to optimize management strategy. Different diagnostic methods that could be of value in the differentiation include radiologic imaging techniques such as CT, MR, and endosonography. In addition, fluid aspiration for cytopathology, tumormarkers or molecular analysis is widely used. Different guidelines are available but so far no optimal diagnostic algorithm exists. We summarize the epidemiology, classification, clinical presentation, diagnostics, management, and future perspectives
Promoting Self-Directed Learning in Simulation-Based Discovery Learning Environments Through Intelligent Support
Longitudinal changes in heart rate after participating in the Groningen Active Living Model (GALM) recreational sports programme
The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement design was conducted; 151 participants were included, providing 398 heart rate files over a period of 18 months. Multi-level analyses were conducted; growth and final models were developed. Significant decreases in mean heart rate over time were observed for all walking speeds. The covariates of sex and body mass index (BMI) were significantly related to mean heart rate at each walking speed, except for BMI at 7 km/h. No significant relationships were observed between energy expenditure for recreational sports activities and leisure-time physical activities and mean heart rate, except for energy expenditure for leisure-time physical activities at 7 km/h. From baseline to December 2002, decreases in predicted mean heart rate were 5.5, 6.0, 10.0, and 9.0 beats/min at walking speeds of 4, 5, 6, and 7 km/h; relative decreases ranged from 5.1 to 7.4%. Significant decreases in heart rate observed during submaximal exercise reflected a potential increase in cardiovascular function after 18 months of participation in the Groningen Active Living Model recreational sports programme. DOI:10.1080/0264041090300874
Highlights lecture EANM 2014: “Gimme gimme gimme those nuclear Super Troupers”
The EANM Congress 2014 took place in Gothenburg, Sweden, from 18 to 22 October under the presidency of Prof. Wim Oyen, chair of the EANM Scientific Committee. Prof. Peter Gjertsson chaired the Local Organizing Committee, according to the standardized EANM congress structure. The meeting was a highlight for the multidisciplinary community that forms the heart and soul of nuclear medicine; attendance was exceptionally high. In total almost 5,300 participants came to Gothenburg, and 1,397 colleagues participated via the EANM LIVE sessions (http://eanmlive.eanm.org/index.php). Participants from all continents were presented with an excellent programme consisting of symposia, scientific and featured sessions, CME sessions, and plenary lectures. These lectures were devoted to nuclear medicine therapy, hybrid imaging and molecular life sciences. Two tracks were included in the main programme, clustering multi-committee involvement: the 5th International Symposium on Targeted Radionuclide-therapy and Dosimetry (ISTARD) and the first Molecules to Man (M2M) track, an initiative of the EANM Committees for Translational Molecular Imaging, Radiopharmacy and Drug Development. The industry made a substantial contribution to the success of the congress demonstrating the latest technology and innovations in the field. During the closing Highlights Lecture, a selection of the best-rated abstracts was presented including diverse areas of nuclear medicine: physics and instrumentation, radiopharmacy, preclinical imaging, oncology (with a focus on the clinical application of newly developed tracers) and radionuclide therapy, cardiology and neurosciences. This Highlights Lecture could only be a brief summary of the large amount of data presented and discussed during the meeting, which can be found in much greater detail in the congress proceedings book, published as Volume 41, Supplement 2 of the European Journal of Nuclear Medicine and Molecular Imaging in October 2014
Novel Surgical Treatment of an Intraretinal Juxtapapillary Hemangioblastoma Using Intraocular Diathermy Forceps:A Case Report
The surgical treatment of intraretinal juxtapapillary retinal hemangioblastomas (JRHs) was previously contraindicated because of the significant risk of collateral damage to the macula and optic nerve. This case report discusses the effectiveness and safety of a novel surgical technique using intraocular bipolar diathermy forceps to coagulate feeder and draining blood vessels of an intraretinal JRH. The patient suffered from bilateral retinal hemangioblastomas with loss of visual function in one eye and the development of an intraretinal JRH in the other eye. Despite intensive treatment with intravitreal bevacizumab and subconjunctival triamcinolone acetonide, growth of the intraretinal JRH continued, macular exudation worsened, and visual acuity decreased. Surgical treatment was undertaken in which, first, the feeder and draining vessels of the JRH were identified by comparing the retinal imaging of the JRH with the imaging before the emergence of the JRH 4 years earlier. Then, retinal incisions were made above the blood vessels and parallel to the nerve fibers during a pars plana vitrectomy. Lastly, these vessels were lifted above the retinal surface and coagulated using intraocular diathermy forceps. Postoperatively, macular edema reduced, and visual acuity increased and remained stable for about 6 months. Using intraocular diathermy forceps, this case report demonstrates effective and safe intraretinal JRH blood vessel coagulation above the retinal surface. This novel surgical approach was able to delay the deterioration of visual acuity due to tumor growth and exudation in this patient. This suggests that coagulation with intraocular diathermy forceps can be considered an additional surgical treatment option for JRHs, especially those with an intraretinal growth pattern.</p
DIACHRONOUS EVOLUTION OF BACK-ARC BASINS IN THE SOUTH TIANSHAN: INSIGHTS FROM STRUCTURAL, GEOCHRONOLOGICAL AND GEOCHEMICAL STUDIES OF THE WUWAMEN OPHIOLITE MÉLANGE
The South Tianshan is located to the north of the Tarim block and defines the southern margin of the Paleozoic Central Asian Orogenic Belt (CAOB). This study presents new structural data, geochronological and geochemical results for the Wuwamen ophiolite mélange in the Chinese segment of the South Tianshan. In the south, the Wuwamen ophiolite mélange shows typical block-in-matrix fabrics and occurs in the footwall of a south-dipping thrust fault, hanging wall of which is composed of weakly metamorphosed and deformed Lower Paleozoic marine to deep marine sequences from the South Tianshan. In the north, a southdipping thrust fault juxtaposes the Wuwamen ophiolite mélange in its hanging wall against the high-grade and strongly deformed metasedimentary rocks from the Central Tianshan in its footwall.The South Tianshan is located to the north of the Tarim block and defines the southern margin of the Paleozoic Central Asian Orogenic Belt (CAOB). This study presents new structural data, geochronological and geochemical results for the Wuwamen ophiolite mélange in the Chinese segment of the South Tianshan. In the south, the Wuwamen ophiolite mélange shows typical block-in-matrix fabrics and occurs in the footwall of a south-dipping thrust fault, hanging wall of which is composed of weakly metamorphosed and deformed Lower Paleozoic marine to deep marine sequences from the South Tianshan. In the north, a southdipping thrust fault juxtaposes the Wuwamen ophiolite mélange in its hanging wall against the high-grade and strongly deformed metasedimentary rocks from the Central Tianshan in its footwall
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