Digital twin control of multi-axis wood CNC machining center based on LinuxCNC

Abstrack: This paper presents an application of an open architecture control system implemented on a multi-axis wood computer numerical control milling machining center, as a digital twin control. The development of the digital twin control system was motivated by research and educational requirements, especially in the field of configuring a new control system by “virtual commissioning”, enabling the validation of the developed controls, program verification, and analysis of the machining process and monitoring. The considered wood computer numerical control (CNC) machining system is supported by an equivalent virtual machine in a computer-aided design and computer-aided manufacturing (CAD/CAM) environment, as well as in the control system, as a digital twin. The configured virtual machines are used for the verification of the machining program and programming system via machining simulation, which is extremely important in multi-axis machining. Several test wood workpieces were machined to validate the effectiveness of the developed control system based on LinuxCNC

USING PROC NLMIXED TO ANALYZE A TIME OF WEED REMOVAL STUDY

Many studies in weed science involve fitting a nonlinear model to experimental data. Examples of such studies include dose-response experiments and studies to determine the critical period of weed control. The experiments typically use block designs and often have additional complexity such as split-plot features. However, nonlinear models are typically fit using software such as SAS PROC NLIN that are limited to a single error term and whose ability to account for blocking is either awkward or lacking entirely. For example, Seefeldt et al. (1995) only proceeded in fitting the nonlinear model after establishing that the block effect was negligible. Issues such as multiple error terms in split-plot designs are simply not dealt with at all. In this paper, we examine a weed removal study carried out as a split-plot design with blocks and illustrate the use of SAS PROC NLMIXED to account for blocks and the two-level error structure

Early-season insect defoliation influences the critical time for weed removal in soybean

To develop more effective pest-management strategies, it is essential to understand how different pests interact with each other and the crop. Field studies were conducted in 2003 and 2004 at two Nebraska locations to determine the effects of early-season crop defoliation on the critical time for weed removal (CTWR) in narrow-row soybean. Three soybean defoliation levels were selected to simulate 0, 30, and 60% leaf tissue removal by the bean leaf beetle. Weeds were allowed to compete with the crop until V2, V4, V6, R3, and R5 growth stages. There were also season-long weedy and weed-free treatments. Results indicated that the CTWR in soybean occurred earlier as defoliation levels increased from 0 to 60%. The CTWR occurred at V3, V2, and V1 growth stage for 0, 30, and 60% defoliation levels, respectively. Overall, 60% defoliation resulted in earlier CTWR by at least 14 d. Yield losses from defoliation and weed interference were primarily associated with a reduction in number of pods per plant-1

EC02-173 Spotted and Diffuse Knapweed

Spotted knapweed (Centaure amaculosa Lam. = C. biebersteinii DC.) and diffuse knapweed (C.diffusa Lam.) are two of Nebraska’s seven noxious weeds. They are also noxious in at least 17 other states. These are closely related species that are well adapted to a variety of habitats including open forests, rangelands and pastures, Conservation Reserve Program lands, roadsides, and ditch banks. Centaurea is a large genus of over 400 species, 32 of which are common weeds of the United States and several of which [e.g., yellowstar thistle, C. solstitalis L, and Russian knapweed, C. repens L. =Acroptilon repens (L.) DC.] have been identified officially as noxious weeds in nearby western states. Other Centaurea species areused as ornamentals. The knapweeds were introduced to the United States from the grasslands of southeastern Europe and Asia. Spotted knapweed now infests more than seven million acres and diffuse knapweed more than three million acres of rangeland and pastures in the western United States

EC02-173 Spotted and Diffuse Knapweed

Spotted knapweed (Centaure amaculosa Lam. = C. biebersteinii DC.) and diffuse knapweed (C.diffusa Lam.) are two of Nebraska’s seven noxious weeds. They are also noxious in at least 17 other states. These are closely related species that are well adapted to a variety of habitats including open forests, rangelands and pastures, Conservation Reserve Program lands, roadsides, and ditch banks. Centaurea is a large genus of over 400 species, 32 of which are common weeds of the United States and several of which [e.g., yellowstar thistle, C. solstitalis L, and Russian knapweed, C. repens L. =Acroptilon repens (L.) DC.] have been identified officially as noxious weeds in nearby western states. Other Centaurea species areused as ornamentals. The knapweeds were introduced to the United States from the grasslands of southeastern Europe and Asia. Spotted knapweed now infests more than seven million acres and diffuse knapweed more than three million acres of rangeland and pastures in the western United States

Reversing resistance to tembotrione in an Amaranthus tuberculatus (var. rudis) population from Nebraska, USA with cytochrome P450 inhibitors

Background: A population of Amaranthus tuberculatus (var. rudis) was confirmed resistant to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicides (mesotrione, tembotrione, and topramezone) in a seed corn/soybean rotation in Nebraska. Further investigation confirmed a non-target-site resistance mechanism in this population. The main objective of this study was to explore the role of cytochrome P450 inhibitors in restoring the efficacy of HPPD-inhibitor herbicides on the HPPD-inhibitor resistant A. tuberculatus population from Nebraska, USA (HPPD-R). Background: A population of Amaranthus tuberculatus (var. rudis) was confirmed resistant to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicides (mesotrione, tembotrione, and topramezone) in a seed corn/soybean rotation in Nebraska. Further investigation confirmed a non-target-site resistance mechanism in this population. The main objective of this study was to explore the role of cytochrome P450 inhibitors in restoring the efficacy of HPPD-inhibitor herbicides on the HPPD-inhibitor resistant A. tuberculatus population from Nebraska, USA (HPPD-R). Results: Enhanced metabolism via cytochrome P450 enzymes is the mechanism of resistance in HPPD-R. Amitrole partially restored the activity of mesotrione, whereas malathion, amitrole, and piperonyl butoxide restored the activity of tembotrione and topramezone in HPPD-R. Although corn was injured through malathion followed by mesotrione application a week after treatment, the injury was transient, and the crop recovered. Includes supplementary file

Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules

New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for their antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. The derivatives showed moderate, nM range antimalarial activities and low cytotoxicity. The N-phenylurea derivative 24 exhibited the best resistance indices (RIW2 = 0.44, RITM91C235 = 0.80) and was not toxic against human normal peripheral blood mononuclear cells (IC50 gt 200 mu M). Seven derivatives were tested in vitro against four human cancer cell lines and they demonstrated high selectivity toward leukaemia K562 cells. One compound, derivative 21 with a primary amino group, was the first tetraoxane tested in vivo against Toxoplasma gondii as another apicomplexan parasite. Subcutaneous administration at a dose of 10 mg kg(-1) day(-1) for 8 days allowed the survival of 20 % of infected mice, thus demonstrating the high potential of tetraoxanes for the treatment of apicomplexan parasites