Peter Handke\u27s Kaspar: The Mechanics of Language—A Fractionating Schizophrenic Theatrical Event

Theatre, for Handke, has neither object nor subject. concepts, values, functional systems of signification, verifiable contents are non existent in Kaspar. Words alone are of import; they alone create reality. Words, therefore, and not subjective evaluations of them, are acceptable to Handke, Comparisons, associations, metaphors, or references prevent people from dealing directly with the object itself (the signified), inviting them to have recourse to a system of differences, to use Derrida\u27s expression, thus contrasting or modifying one with the other. Evaluation breeds buffers and hierarchies; it encourages people to rank or compute ideas, notions, or feelings, and therefore prolong illusionism. Reality is not approached forthrightly, but rather experienced through a system of signs—a cultural product. This study aims at discovering Handke\u27s innovative and challenging ideas concerning his manner of subverting conventional systems of relationships and comparisions. Words and figures of speech, as used in Kaspar, are mechanical devices endowed with concretion. Hard, unyielding, feelingless, these machine-like abstractions bludgeon into submission, cutting and dismantling well-worn responses to old ways of thinking and understanding. How the dramatist accomplishes his goals is analyzed

Nathalie Sarraute\u27s Between Life and Death: Androgyny and the Creative Process

Nathalie Sarraute\u27s Between Life and Death deals with the creative process, from the uncreated work of art embedded in the prima materia to its completion in the book. The Writer, the focus of Sarraute\u27s attention, takes the reader through the multiple stages of his literary trajectory: the struggle involved in the transmutation of the amorphous word into the concrete glyph on the blank sheet of paper; the pain and anguish accompanying the birth of the created work, alluded to as the thing or the object ; the attitude of the successful Writer, who postures and panders to his public, and the rebirth of the creative élan following an inner vision. How does the Writer, like the ancient rates inject life into what has previously been dead, or uncreated: the written word? How does the course of the word from the uncreated to concretion in the empirical world affect both the Writer—as androgyne—and the reader during the happenings in Between Life and Death

Inferring causal molecular networks: empirical assessment through a community-based effort

Inferring molecular networks is a central challenge in computational biology. However, it has remained unclear whether causal, rather than merely correlational, relationships can be effectively inferred in complex biological settings. Here we describe the HPN-DREAM network inference challenge that focused on learning causal influences in signaling networks. We used phosphoprotein data from cancer cell lines as well as in silico data from a nonlinear dynamical model. Using the phosphoprotein data, we scored more than 2,000 networks submitted by challenge participants. The networks spanned 32 biological contexts and were scored in terms of causal validity with respect to unseen interventional data. A number of approaches were effective and incorporating known biology was generally advantageous. Additional sub-challenges considered time-course prediction and visualization. Our results constitute the most comprehensive assessment of causal network inference in a mammalian setting carried out to date and suggest that learning causal relationships may be feasible in complex settings such as disease states. Furthermore, our scoring approach provides a practical way to empirically assess the causal validity of inferred molecular networks

Inferring causal molecular networks: empirical assessment through a community-based effort

It remains unclear whether causal, rather than merely correlational, relationships in molecular networks can be inferred in complex biological settings. Here we describe the HPN-DREAM network inference challenge, which focused on learning causal influences in signaling networks. We used phosphoprotein data from cancer cell lines as well as in silico data from a nonlinear dynamical model. Using the phosphoprotein data, we scored more than 2,000 networks submitted by challenge participants. The networks spanned 32 biological contexts and were scored in terms of causal validity with respect to unseen interventional data. A number of approaches were effective, and incorporating known biology was generally advantageous. Additional sub-challenges considered time-course prediction and visualization. Our results suggest that learning causal relationships may be feasible in complex settings such as disease states. Furthermore, our scoring approach provides a practical way to empirically assess inferred molecular networks in a causal sense

Women, myth, and the feminine principle

Women, Myth, and the Feminine Principle focuses on the role played by women in specific religious texts, epic poems, theater pieces, and tales narrating sacred events in which Deities and supernatural or extraordinary beings move through their difficult celestial and earthly trajectories.xviii, 250 hlm.; 23 c

Women, Myth, and The Feminine Principle

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Peter Handke's Kaspar: The Mechanics of Language—A Fractionating Schizophrenic Theatrical Event

Theatre, for Handke, has neither object nor subject. concepts, values, functional systems of signification, verifiable contents are non existent in Kaspar . Words alone are of import; they alone create reality. Words, therefore, and not subjective evaluations of them, are acceptable to Handke, Comparisons, associations, metaphors, or references prevent people from dealing directly with the object itself (the signified ), inviting them to have recourse to a "system of differences," to use Derrida's expression, thus contrasting or modifying one with the other. Evaluation breeds buffers and hierarchies; it encourages people to rank or compute ideas, notions, or feelings, and therefore prolong illusionism. Reality is not approached forthrightly, but rather experienced through a system of signs—a cultural product. This study aims at discovering Handke's innovative and challenging ideas concerning his manner of subverting conventional systems of relationships and comparisions. Words and figures of speech, as used in Kaspar , are mechanical devices endowed with concretion. Hard, unyielding, feelingless, these machine-like abstractions bludgeon into submission, cutting and dismantling well-worn responses to old ways of thinking and understanding. How the dramatist accomplishes his goals is analyzed