184 research outputs found

    Ideology and Entry Policy: Why Non-Socialist Parties in Sweden Support Open Door Migration Policies

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    While the continued growth of far-right populist parties across Europe has led to a rich body of literature detailing the impact of anti-immigrant parties on entry policies, less attention has been directed towards analyzing how mainstream non-socialist parties formulate their migration policy preferences. In this paper, we seek to correct this imbalance by addressing the case of Sweden. The conventional wisdom frequently portrays non-socialist parties as proponents of restrictive entry policies for labor migrants and asylum seekers. However, we show that center-right parties and the Greens have largely been the driving force behind key Swedish migration policy developments over the past several decades, allowing greater numbers of migrants to enter and settle permanently. Our analysis shows that non-socialist support for generous entry policies is largely consistent over time, regardless of efforts by far-right populist parties, or the socialist left, to see more restrictive entry policies enacted. To account for this stance, we focus on the role of party ideology as the missing factor. While vote maximization and inter-party competition have their place in accounts of entry policy preference formation, a more nuanced analysis requires examining the role of ideology. Long-held ideological principles help parties evaluate societal change, leading them to formulate generous entry policies in the face of pressure from both the left and the right for stricter migration policies

    Phase Retrieval for Partially Coherent Observations

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    Phase retrieval is in general a non-convex and non-linear task and the corresponding algorithms struggle with the issue of local minima. We consider the case where the measurement samples within typically very small and disconnected subsets are coherently linked to each other - which is a reasonable assumption for our objective of antenna measurements. Two classes of measurement setups are discussed which can provide this kind of extra information: multi-probe systems and holographic measurements with multiple reference signals. We propose several formulations of the corresponding phase retrieval problem. The simplest of these formulations poses a linear system of equations similar to an eigenvalue problem where a unique non-trivial null-space vector needs to be found. Accurate phase reconstruction for partially coherent observations is, thus, possible by a reliable solution process and with judgment of the solution quality. Under ideal, noise-free conditions, the required sampling density is less than two times the number of unknowns. Noise and other observation errors increase this value slightly. Simulations for Gaussian random matrices and for antenna measurement scenarios demonstrate that reliable phase reconstruction is possible with the presented approach.Comment: 12 pages, 14 figure

    Linear Phase Retrieval for Near-Field Measurements with Locally Known Phase Relations

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    A linear and thus convex phase retrieval algorithm for the application in phaseless near-field far-field transformations is presented. The formulation exploits locally known phase relations among sets of measurement samples, which can in practice be acquired with multi-channel receivers. Due to the linearity of the formulation, a reliable phaseless transformation is achieved, which completely avoids the problem of local minima - the Achilles heel of most existing phase retrieval techniques. Furthermore, the necessary number of measurements are kept close to that of fully-coherent antenna measurements. Comparisons with an already existing approach exploiting local phase relations demonstrate the accuracy and reliability for synthetic data.Comment: 5 pages, 3 figures, 1 table, submitted to the 15th European Conference on Antennas and Propagation 2021 (EuCAP

    Autonomous Load Profile Recognition in Industrial DC-Link Using an Audio Search Algorithm

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    Industrial manufacturing plants, including machine tools, robots, and elevators, perform dynamic acceleration and braking processes. Recuperative braking results in an increased voltage in the machines' direct current (DC) links. In the case of a diode rectifier, a braking resistor turns the surplus of energy into lost heat. In contrast, active rectifiers can feed the braking energy back to the AC grid, though they are more expensive than diode rectifiers. DC link-coupled energy storage systems are one possible solution to downsize the supply infrastructure by peak shaving and to harvest braking energy. However, their control heavily depends on the applied load profiles that are not known in advance. Especially for retrofitted energy storage systems without connection to the machine control unit, load profile recognition imposes a major challenge. A self-tuning framework represents a suitable solution by covering system identification, proof of stability, control design, load profile recognition, and forecasting at the same time. This paper introduces autonomous load profile recognition in industrial DC links using an audio search algorithm. The method generates fingerprints for each measured load profile and saves them in a database. The control of the energy storage system then has to be adapted within a critical time range according to the identified load profile and constraints given by the energy storage system. Three different load profiles in four case studies validate the methodology

    Source Management In DC Microgrids: An Industrial Application

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    Industrial direct current (DC) microgrids offer multiple advantages for production factories. They enable higher energy and resource efficiency not only for the production energy supply but also for integrating renewable energy resources. The basic control method of DC microgrids, namely droop control, fits the industrial application due to its decentralized and robust nature. However, in the case of droop control, the DC bus voltage deviates from the nominal value for slowly fluctuating load situations. For this reason, an additional control level for voltage restoration, called secondary control or source management, is necessary. This paper presents hierarchical control for voltage restoration in industrial DC microgrids. The control shifts the current supplied to the DC bus in case the load increases over or decreases below a defined voltage band for a certain period. In addition, the designed control is tested on a real industrial DC microgrid which includes typical industrial loads of up to 50 kW, such as robots of different sizes and CNC machine tools. The control performance with different parameters of the source management is assessed. The results show that the designed control restores the voltage level without creating instabilities in the microgrid for all tested scenarios

    Powikłania wymiany stymulatora serca — opis przypadku pacjentki z zakrzepicą żył głębokich kończyny górnej

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    Deep venous thrombosis of the upper extremity (UEDVT) after pacemaker implantation (PM) is often an underestimated problem, but should be considered as a potential complication, because the number of implanting PM is increasing every year. This case report presents a history of a 57-years old woman with a pacemaker implanted in 1996 due to the 3rd-degree atrioventricular block. The patient was admitted to the hospital for the replacement of the stimulating system. The procedure was complicated by hemorrhage from the pocket of the device and in the postoperative period — the left upper extremity deep vein thrombosis.Zakrzepica żył głębokich kończyny górnej po implantacji stymulatora serca jest często bagatelizowanym problemem, chociaż powinna być brana pod uwagę jako potencjalne powikłanie zabiegu w związku z rosnącą liczbą implantowanych stymulatorów serca każdego roku. W niniejszym tekśćie opisano przypadek 57-letniej pacjentki po wszczepieniu stymulatora serca z powodu bloku przedsionkowo-komorowego III stopnia w 1996 r., która została przyjęta do szpitala w celu wymiany urządzenia. Zabieg był powikłany krwawieniem z loży stymulatora oraz masywną zakrzepicą żył głębokich kończyny górnej lewej w okresie pozabiegowym

    Automated Real-Time Control of Fluidic Self-Assembly of Microparticles

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    Self-assembly is a key coordination mechanism for large multi-unit systems and a powerful bottom-up technology for micro/nanofabrication. Controlled self-assembly and dynamic reconfiguration of large ensembles of microscopic particles can effectively bridge these domains to build innovative systems. In this perspective, we present SelfSys, a novel platform for the automated control of the fluidic self-assembly of microparticles. SelfSys centers around a water-filled microfluidic chamber whose agitation modes, induced by a coupled ultrasonic actuator, drive the assembly. Microparticle dynamics is imaged, tracked and analyzed in real-time by an integrated software framework, which in turn algorithmically controls the agitation modes of the microchamber. The closed control loop is fully automated and can direct the stochastic assembly of microparticle clusters of preset dimension. Control issues specific to SelfSys implementation are discussed, and its potential applications presented. The SelfSys platform embodies at microscale the automated self-assembly control paradigm we first demonstrated in an earlier platform

    Accuracy and Conditioning of Surface-Source Based Near-Field to Far-Field Transformations

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    The conditioning and accuracy of various inverse surface-source formulations are investigated. First, the normal systems of equations are discussed. Second, different implementations of the zero-field condition are analyzed regarding their effect on solution accuracy, conditioning, and source ambiguity. The weighting of the Love-current side constraint is investigated in order to provide an accurate problem-independent methodology. The transformation results for simulated and measured near-field data show a comparable behavior regarding accuracy and conditioning for most of the formulations. Advantages of the Love-current solutions are found only in diagnostic capabilities. Regardless of this, the Love side constraint is a computationally costly way to influence the iterative solver threshold, which is more conveniently controlled with the appropriate type of normal equation. The solution behavior of the inverse surface-source formulations is mostly influenced by the choice of the reconstruction surface. A spherical Huygens surface leads to the best conditioning, whereas the most accurate solutions are found with a tight, possibly convex hull around the antenna under test.Comment: 15 pages, 13 figures, 4 tables, accepted for publication in IEEE Transactions on Antennas and Propagatio

    DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma

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    The two p53 homologues p63 and p73 regulate transcriptional programs in epithelial tissues and several cell types in these tissues express both proteins. All members of the p53 family form tetramers in their active state through a dedicated oligomerization domain that structurally assembles as a dimer of dimers. The oligomerization domain of p63 and p73 share a high sequence identity, but the p53 oligomerization domain is more divergent and it lacks a functionally important C-terminal helix present in the other two family members. Based on these structural differences, p53 does not hetero-oligomerize with p63 or p73. In contrast, p63 and p73 form hetero-oligomers of all possible stoichiometries, with the hetero-tetramer built from a p63 dimer and a p73 dimer being thermodynamically more stable than the two homo-tetramers. This predicts that in cells expressing both proteins a p632_{2}/p732_{2} hetero-tetramer is formed. So far, the tools to investigate the biological function of this hetero-tetramer have been missing. Here we report the generation and characterization of Designed Ankyrin Repeat Proteins (DARPins) that bind with high affinity and selectivity to the p632_{2}/p732_{2} hetero-tetramer. Using these DARPins we were able to confirm experimentally the existence of this hetero-tetramer in epithelial mouse and human tissues and show that its level increases in squamous cell carcinoma

    Identification of de novo variants in nonsyndromic cleft lip with/without cleft palate patients with low polygenic risk scores

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    [Background]: Nonsyndromic cleft lip with/without cleft palate (nsCL/P) is a congenital malformation of multifactorial etiology. Research has identified >40 genome-wide significant risk loci, which explain less than 40% of nsCL/P heritability. Studies show that some of the hidden heritability is explained by rare penetrant variants. [Methods]: To identify new candidate genes, we searched for highly penetrant de novo variants (DNVs) in 50 nsCL/P patient/parent-trios with a low polygenic risk for the phenotype (discovery). We prioritized DNV-carrying candidate genes from the discovery for resequencing in independent cohorts of 1010 nsCL/P patients of diverse ethnicities and 1574 population-matched controls (replication). Segregation analyses and rare variant association in the replication cohort, in combination with additional data (genome-wide association data, expression, protein–protein-interactions), were used for final prioritization. [Conclusion]: In the discovery step, 60 DNVs were identified in 60 genes, including a variant in the established nsCL/P risk gene CDH1. Re-sequencing of 32 prioritized genes led to the identification of 373 rare, likely pathogenic variants. Finally, MDN1 and PAXIP1 were prioritized as top candidates. Our findings demonstrate that DNV detection, including polygenic risk score analysis, is a powerful tool for identifying nsCL/P candidate genes, which can also be applied to other multifactorial congenital malformations.The present study was supported by the German Research Foundation (DFG)-Grants BE 3828/8-1, LU 1944/2-1, MA 2546/5-1, and LU1944/3-1
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