160 research outputs found
Lymphocyte count in peripheral blood is a sensitive tool in pretreatment assessment of patients with urological cancer
Cancer, inflammation and immune surveillance recruit lymphocytes as common key cellular players. The aim of the study was to assess a utility of the absolute and relative lymphocyte counts (ALC and RLC) in peripheral blood of patients with urological cancer as sensitive tool in pretreatment assessment of patient, which correlates with postoperative outcome of the disease, and outlines the overall reactivity of the patient. Materials and Methods: We retrospectively studied correlation between lymphocyte count in peripheral blood of the patients with urological cancer (n = 789) and number of clinical parameters: cancer localization, stage of the disease, treatment outcome, complications. Mann β Whitney two-tailed test and logistic regression models were used. Results: Lymphocyte counts (both absolute and relative) correlate with the cancer stage, and status of the disease, allowing differentiate patients with urological cancer, from healthy individuals, and from the cancer patients after radical surgery. In patients with kidney and bladder cancer, lymphocyte count allowed differentiate the stages of the disease. Lower rate of the reactivity of the patient to the cancer treatment is accurately predicted by the ALC and RLC: those in highest quartile for lymphocytes count have shorter postoperative recovery. Patients in lowest quartile demonstrated worst postoperative performance, including cases of early postoperative mortality due to weak somatic status. Conclusion: The study presents evidence that pretreatment lymphocyte count in the peripheral blood of patients with urological cancer is a sensitive marker of cancer stage, and the reactivity of the patient to the cancer treatment, which can be used in the pretreatment assessment of the patient. Key Words: urological cancer, lymphocytes, postoperative morbidity, reactivity, immune status assessment, treatment outcome
Dynamic changes of Au/ZnO catalysts during methanol synthesis: A model study by temporal analysis of products (TAP) and Zn L<sub>III</sub> near Edge X-Ray absorption spectroscopy
Small gold nanoparticles supported on ZnO have been identified as highly active and selective catalysts for the green synthesis of methanol from CO2 and H2. Furthermore, they can serve also a model system for the mechanistic understanding of methanol synthesis on the industrial Cu/ZnO catalyst. The dynamic changes in the structure of Au/ZnO upon exposure to methanol synthesis gas mixtures were studied using a combination of TAP reactor and near edge X-ray absorption spectroscopy (XANES) measurements at the Zn LIII edge, both in CO2/H2 and CO/H2 gas mixtures. TAP measurements indicated that CO can create significant amounts of O-vacancy defects in ZnO at 240Β°C, while CO2 can re-oxidize a pre-reduced catalyst or maintain this state in the presence of s trongly reducing gases (CO and H2). Furthermore, CO2 present as reactant or resulting from the reactive removal of surface lattice oxygen by interaction with CO can be deposited on the pre-reduced Au/ZnO surface as stable adsorbed carbon containing species, e.g., as surface carbonates, which decompose at Tβ₯250Β°C. In situ XANES measurements at the Zn LIII edge revealed that ZnO is significantly reduced during reaction, both in CO2/H2 and CO/H2 gas mixtures, but with the extent of the reduction being more pronounced in CO/H2 than in CO2/H2. These results will be critically discussed in the light of previous findings on the role of ZnO reduction in the activity of methanol synthesis catalysts
ΠΠΠΠ£ΠΠΠΠΠΠΠ§ΠΠ‘ΠΠΠ ΠΠ‘ΠΠΠΠΠΠΠ‘Π’Π Π₯Π ΠΠΠΠ§ΠΠ‘ΠΠΠΠ ΠΠΠ‘Π’Π’Π ΠΠΠΠΠ’ΠΠ§ΠΠ‘ΠΠΠΠ ΠΠ‘Π’ΠΠΠΠΠΠΠΠ’Π
A comparative study of cellular immunity parameters was performed in patients with long bone chronic posttraumatic osteomyelitis in regard to osteomyelitis stages. Thirty patients with the fistulous form of long bone chronic posttraumatic osteomyelitis and 13 patients with long bone chronic posttraumatic osteomyelitis in the remission stage were examined using laser flow citometry. It was revealed that a moderate leukocytosis, increased monocyte and neutrophile absolute number as well as increased CD25 and HLA-DR-positive T-lymphocyte number are typical for chronic osteomyelitis regardless of the pathological process stages. The remission stage in patients with chronic posttraumatic osteomyelitis is accompanied by moderate activation of humoral immunity (increased B-lymphocyte (CD19+) number and increased production of IgG). The decrease in the peripheral blood lymphocyte number and well as reduction of HLA-DR expression on monocytes creates prerequisites for the development of fistulous osteomyelitis form and can be an indication for administering the preparations of immunomodulating action.ΠΡΠΎΠ²Π΅Π΄ΡΠ½ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡΠ½ΠΈΡΠ΅ΡΠ° Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠΎΠΌ Π΄Π»ΠΈΠ½Π½ΡΡ
ΠΊΠΎΡΡΠ΅ΠΉ Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΡΡΠ°Π΄ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ. ΠΠ΅ΡΠΎΠ΄ΠΎΠΌ Π»Π°Π·Π΅ΡΠ½ΠΎΠΉ ΠΏΡΠΎΡΠΎΡΠ½ΠΎΠΉ ΡΠΈΡΠΎΠΌΠ΅ΡΡΠΈΠΈ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 30 Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠΎ ΡΠ²ΠΈΡΠ΅Π²ΠΎΠΉ ΡΠΎΡΠΌΠΎΠΉ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΡΡΡΡΠ°Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠ° ΠΈ 13 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΏΠΎΡΡΡΡΠ°Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠΎΠΌ Π΄Π»ΠΈΠ½Π½ΡΡ
ΠΊΠΎΡΡΠ΅ΠΉ Π² ΡΡΠ°Π΄ΠΈΠΈ ΡΠ΅ΠΌΠΈΡΡΠΈΠΈ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π΄Π»Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠ°, Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΠΎ ΠΎΡ ΡΡΠ°Π΄ΠΈΠΈ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°, Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ΅Π½ ΡΠΌΠ΅ΡΠ΅Π½Π½ΡΠΉ Π»Π΅ΠΉΠΊΠΎΡΠΈΡΠΎΠ·, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ Π°Π±ΡΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΠΌΠΎΠ½ΠΎΡΠΈΡΠΎΠ² ΠΈ Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»ΠΎΠ², ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΡΠΈΡΠ»Π° CD25 ΠΈ HLA-DR - ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
Π’-Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ². Π‘ΡΠ°Π΄ΠΈΡ ΡΠ΅ΠΌΠΈΡΡΠΈΠΈ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΏΠΎΡΡΡΡΠ°Π²ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠΎΠΌ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π΅ΡΡΡ ΡΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠ΅ΠΉ Π³ΡΠΌΠΎΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΌΡΠ½ΠΈΡΠ΅ΡΠ° (ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° Π-Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ² (CD19+) ΠΈ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠΈ IgG). Π‘Π½ΠΈΠΆΠ΅Π½ΠΈΠ΅ Π² ΠΏΠ΅ΡΠΈΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΡΠΎΠ²ΠΈ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ², Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠΈ HLA-DR Π½Π° ΠΌΠΎΠ½ΠΎΡΠΈΡΠ°Ρ
ΡΠΎΠ·Π΄Π°ΡΡ ΠΏΡΠ΅Π΄ΠΏΠΎΡΡΠ»ΠΊΠΈ Π΄Π»Ρ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ²ΠΈΡΠ΅Π²ΠΎΠΉ ΡΠΎΡΠΌΡ ΠΎΡΡΠ΅ΠΎΠΌΠΈΠ΅Π»ΠΈΡΠ° ΠΈ ΠΌΠΎΠΆΠ΅Ρ ΡΠ»ΡΠΆΠΈΡΡ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠ΅ΠΌ Π΄Π»Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² ΠΈΠΌΠΌΡΠ½ΠΎΠΌΠΎΠ΄ΡΠ»ΠΈΡΡΡΡΠ΅Π³ΠΎ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠ΅ΡΠΈΠΏΡΠΎΡΠ΅Π·Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ ΠΊΡΡΠΏΠ½ΡΡ ΡΡΡΡΠ°Π²ΠΎΠ² Ρ ΠΠΠ§-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ
Relevance. There is a limited number of publications reporting outcomes of primary large joint arthroplasty inΒ patients with human immunodeficiency virus (HIV). The authors were unable to find papers on revision arthroplastyΒ in patients with periprosthetic infection. Purpose of the study β to evaluate short term outcomes after revisionΒ arthroplasty in HIV-positive patients with periprosthetic infection of the hip and knee joint. Materials and methods.Β 13 HIV-positive patients with periprosthetic infection of the hip (10 cases) and knee (3 cases) joint underwentΒ treatment in the period from 2015 to 2019. Patients were examined by clinical, laboratory and roentgenologicalΒ methods. Harris Hip Score and Knee Society Score were used for evaluation prior to and after the surgery. Results.Β Mean follow up period was 21,4Β±2,6 months. Successful two-stage treatment was performed in two (15,4%) outΒ of 13 patients with periprosthetic infection. In 5 cases (38,5%) control over infection was achieved by resectionΒ arthroplasty, and in one case (7,7%) β by arthrodesis. Five patients (38,5%) refused from interchange of spacer toΒ prosthesis. Mean Harris Hip score demonstrated insignificant increase postoperatively β from 45,3Β±2,2 to 52,2Β±4,15Β (Ρ = 0,2). Conclusion. Despite following the international protocols for treatment of implant-associated infection theΒ infection recurrence rate in HIV-positive patients in the asymptomatic phase remains very high. Efficiency of twostageΒ treatment using antibacterial spacers in the present group of patients amounted only to 15,4%.ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ. Π‘ΡΡΠ΅ΡΡΠ²ΡΠ΅Ρ ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½Π½ΠΎΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΉ, Π² ΠΊΠΎΡΠΎΡΡΡ
ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠ³ΠΎ ΡΠ½Π΄ΠΎΠΏΡΠΎΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΊΡΡΠΏΠ½ΡΡ
ΡΡΡΡΠ°Π²ΠΎΠ² Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π²ΠΈΡΡΡΠΎΠΌ ΠΈΠΌΠΌΡΠ½ΠΎΠ΄Π΅ΡΠΈΡΠΈΡΠ° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° (ΠΠΠ§). ΠΡΒ Π½Π΅ ΡΠΌΠΎΠ³Π»ΠΈ ΠΎΠ±Π½Π°ΡΡΠΆΠΈΡΡ ΡΠ°Π±ΠΎΡ, ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π½ΡΡ
ΡΠ΅Π²ΠΈΠ·ΠΈΠΎΠ½Π½ΠΎΠΌΡ ΡΠ½Π΄ΠΎΠΏΡΠΎΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΏΠ΅ΡΠΈΠΏΡΠΎΡΠ΅Π·Π½ΠΎΠΉΒ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ. Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΎΡΠ΅Π½ΠΈΡΡ ΠΊΡΠ°ΡΠΊΠΎΡΡΠΎΡΠ½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ΅Π²ΠΈΠ·ΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΡΠ½Π΄ΠΎΠΏΡΠΎΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½ΠΈΡΒ Ρ ΠΠΠ§-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π½Π°Π»ΠΈΡΠΈΠ΅ΠΌ ΠΏΠ΅ΡΠΈΠΏΡΠΎΡΠ΅Π·Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ ΡΠ°Π·ΠΎΠ±Π΅Π΄ΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΈ ΠΊΠΎΠ»Π΅Π½Π½ΠΎΠ³ΠΎ ΡΡΡΡΠ°Π²ΠΎΠ².Β ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ° ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ 2015 Π³. ΠΏΠΎ 2019 Π³. Π½Π° Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π² ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ Π½Π°Ρ
ΠΎΠ΄ΠΈΠ»ΠΎΡΡ 13 ΠΠΠ§-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΏΠ΅ΡΠΈΠΏΡΠΎΡΠ΅Π·Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ ΡΠ°Π·ΠΎΠ±Π΅Π΄ΡΠ΅Π½Π½ΠΎΠ³ΠΎ (10 ΡΠ»ΡΡΠ°Π΅Π²) ΠΈ ΠΊΠΎΠ»Π΅Π½Π½ΠΎΠ³ΠΎ (3 ΡΠ»ΡΡΠ°Ρ) ΡΡΡΡΠ°Π²ΠΎΠ².Β Π‘ΠΎΡΡΠΎΡΠ½ΠΈΠ΅Β ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΎΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ ΠΏΡΠΈ ΠΏΠΎΠΌΠΎΡΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
, Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΡ
, ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ². ΠΡΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡΒ ΠΎΡΠ΅Π½ΠΊΠ° ΠΏΠΎ ΡΠΊΠ°Π»Π΅ Harris Hip Score ΠΈ Knee Society Score Π΄ΠΎ ΠΈ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π‘ΡΠ΅Π΄Π½ΠΈΠΉ ΡΡΠΎΠΊ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ ΡΠΎΡΡΠ°Π²ΠΈΠ» 21,4Β±2,6 ΠΌΠ΅Ρ. Π£ Π΄Π²ΡΡ
(15,4%) ΠΈΠ· 13 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΏΠ΅ΡΠΈΠΏΡΠΎΡΠ΅Π·Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π±ΡΠ»ΠΎ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΡΡΠΏΠ΅ΡΠ½ΠΎΠ΅ Π΄Π²ΡΡ
ΡΡΠ°ΠΏΠ½ΠΎΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΠ΅. Π ΠΏΡΡΠΈ ΡΠ»ΡΡΠ°ΡΡ
(38,5%) ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π½Π°Π΄ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π±ΡΠ» Π΄ΠΎΡΡΠΈΠ³Π½ΡΡ ΠΏΡΡΠ΅ΠΌΒ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ ΡΠ΅Π·Π΅ΠΊΡΠΈΠΎΠ½Π½ΠΎΠΉ Π°ΡΡΡΠΎΠΏΠ»Π°ΡΡΠΈΠΊΠΈ ΠΈ Π΅ΡΠ΅ Π² ΠΎΠ΄Π½ΠΎΠΌ (7,7%) β Ρ ΠΏΠΎΠΌΠΎΡΡΡ Π°ΡΡΡΠΎΠ΄Π΅Π·Π°. ΠΡΡΠ΅ΡΠΎ Π±ΠΎΠ»ΡΠ½ΡΡ
Β (38,5%) ΠΎΡΠΊΠ°Π·Π°Π»ΠΈΡΡ ΠΎΡ Π·Π°ΠΌΠ΅Π½Ρ ΡΠΏΠ΅ΠΉΡΠ΅ΡΠ° Π½Π° ΡΠ½Π΄ΠΎΠΏΡΠΎΡΠ΅Π·. Π‘ΡΠ΅Π΄Π½ΡΡ ΠΎΡΠ΅Π½ΠΊΠ° ΠΏΠΎ HHS Π²ΠΎΠ·ΡΠΎΡΠ»Π° Π½Π΅Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ βΒ Ρ 45,3Β±2,2 Π΄ΠΎ 52,2Β±4,15 Π±Π°Π»Π»ΠΎΠ² ΠΏΠΎΡΠ»Π΅ Π»Π΅ΡΠ΅Π½ΠΈΡ (Ρ = 0,2). ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ΅ΡΠΌΠΎΡΡΡ Π½Π° ΡΠΎΠ±Π»ΡΠ΄Π΅Π½ΠΈΠ΅ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ
Β ΠΏΡΠΎΡΠΎΠΊΠΎΠ»ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°Ρ-Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ, ΡΠ°ΡΡΠΎΡΠ° ΡΠ΅ΡΠΈΠ΄ΠΈΠ²ΠΎΠ² Ρ ΠΠΠ§-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
Β Π² Π±Π΅ΡΡΠΈΠΌΠΏΡΠΎΠΌΠ½ΠΎΠΉ ΡΡΠ°Π΄ΠΈΠΈ ΠΎΡΡΠ°Π΅ΡΡΡ ΠΎΡΠ΅Π½Ρ Π²ΡΡΠΎΠΊΠΎΠΉ. ΠΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π΄Π²ΡΡ
ΡΡΠ°ΠΏΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌΒ Π°Π½ΡΠΈΠ±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΏΠ΅ΠΉΡΠ΅ΡΠ° Π² Π½Π°ΡΠ΅ΠΉ Π³ΡΡΠΏΠΏΠ΅ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠΎΡΡΠ°Π²ΠΈΠ»Π° Π»ΠΈΡΡ 15,4%
Investigation of Electrocatalysts Produced by a Novel Thermal Spray Deposition Method
Common methods to produce supported catalysts include impregnation, precipitation, and thermal spray techniques. Supported electrocatalysts produced by a novel method for thermal spray deposition were investigated with respect to their structural properties, elemental composition, and electrochemical performance. This was done using electron microscopy, X-ray photoelectron spectroscopy, and cyclic voltammetry. Various shapes and sizes of catalyst particles were found. The materials exhibit different activity towards oxidation and reduction of Fe. The results show that this preparation method enables the selection of particle coverage as well as size and shape of the catalyst material. Due to the great variability of support and catalyst materials accessible with this technique, this approach is a useful extension to other preparation methods for electrocatalysts
Ein aktiver und stabiler Cobaltkatalysator fΓΌr die Sauerstoffentwicklungsreaktion: Polymerisation einer ionischen FlΓΌssigkeit
Inspiriert durch die katalytischen Eigenschaften von Single-site-Katalysatoren und der erhΓΆhten LeistungsfΓ€higkeit von Metallkatalysatoren durch ionische FlΓΌssigkeiten wurde eine Methode zur gezielten und skalierbaren Platzierung von einzelnen Cobaltatomen auf KohlenstoffnanorΓΆhrenoberflΓ€chen mithilfe einer polymerisierten ionischen FlΓΌssigkeit entwickelt. Durch eine ionische FlΓΌssigkeit wurden einzelne, fein verteilte Cobaltionen koordiniert und als heterogener Katalysator fΓΌr die Sauerstoffententwicklungsreaktion (OER) genutzt. Die erhaltenen Daten zeigen eine hohe AktivitΓ€t bei gleichzeitig vorhandener StabilitΓ€t
A new test for unimodality
A distribution function (d.f.) of a random variable is unimodal if there exists a number such that d.f. is convex left from this number and is concave right from this number. This number is called a mode of d.f. Since one may have more than one mode, a mode is not necessarily unique. The purpose of this paper is to construct nonparametric tests for the unimodality of d.f. based on a sample obtained from the general population of values of the random variable by simple sampling. The tests proposed are significance tests such that the unimodality of d.f. can be guaranteed with some probability (confidence level)
Strong Metal Support Interaction as a Key Factor of Au Activation in CO Oxidation
We address the question of the nature of Au NP activation and through a combination of experimental and theoretical techniques. In situ XPS measurements of Au TiO2 during CO oxidation show high catalytic activity can be associated with the formation of an ionic Au species. DFT calculations performed on Au TiO2 show that the formation of such ionic Au is due to a strong metal support interaction between Au and reduced and defective TiO2. TEM supports these findings, indicating the formation of an overlayer of transition metal oxide support on Au NPs after CO oxidation. These results suggest TiO2 lattice oxygen is involved directly in CO oxidation, which was confirmed with labeled 18O2 experiment
Digital technologies in the tax sphere as a factor in the sustainability of economic activity
In the future, digital technologies will make it possible to increase the transparency of the economic activities of tax organizations, the transparency of the economy of all economic entities in Russian Federation, which guarantees the stability of receipts to the country's budget, an improvement in the quality of budget planning and economic stability. The purpose of this study is to substantiate the optimization of the economic activities of tax organizations based on the introduction of digital technologies. The object of the research is the economic activity of tax organizations. The subject of the research is digital technologies as a factor in optimizing economic activity and the sustainability of tax organizations. The analysis of the efficiency of tax organizations is presented. The author's vision of the influence of digital technologies on the optimization of economic activity is given on the example of the branch of the Federal Tax Service of the Russian Federation in terms of tax control and the provision of public services. It is concluded that the optimization of the economic activities of tax organizations based on the introduction of digital technologies will reduce the costs of current activities, tax administration, time costs for tax transactions
βSmartβ transport and logistics complex as a factor of sustainable development of the region (on the example of the Volgograd region)
At the present stage of social development, which is forming a new high-tech world system with all its challenges and problems, it is necessary to provide all participants in social and economic relations with a single and convenient environment for interaction, to improve the level and quality of life, and to ensure sustainable development. Β«Smart cityΒ» technologies, and their further extrapolation to the scale of a regional entity β a Β«smart regionΒ» β make it possible to ensure sustainable development for all residents of the region and consumers of municipal and regional services β citizens, public and business organizations, as well as government. Due to the constant development of the transport industry and new opportunities for the transportation of passengers and goods, it is interesting to study the transport and logistics segment of the Β«smart regionΒ». It explains the relevance and practical significance of this study, which presents a theoretical and methodological substantiation of the formation of a Β«smartΒ» transport and logistics complex with its positioning as a factor of sustainable development of the region, on the example of the Volgograd region. This approach is original, has a high degree of reliability, the ability to build and verify the forecast of the socio-economic development of the region. The developed model in the study represents the authors' vision of the development of the transport and logistics complex of the Volgograd region in the future, defines short, medium and long-term priorities, goals and objectives, proposes the main directions of development, mechanisms for achieving the set goals and objectives, taking into account the achieved level and identified problems. The results of approbation prove the expediency of its use in the development and scientific substantiation of the strategy of socio-economic development at the regional level
- β¦