136 research outputs found

    An integrative model of the personal growth process in a T-group

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    Thesis (S.M.)--Massachusetts Institute of Technology, Sloan School of Management, 1970.Includes bibliographical references (leaves 72-74).by Stanley David Quint and Aaron Kleiner.S.M

    WALLABY Early Science - I. The NGC 7162 Galaxy Group

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    We present Widefield ASKAP L-band Legacy All-sky Blind Survey (WALLABY) early science results from the Australian Square Kilometre Array Pathfinder (ASKAP) observations of the NGC 7162 galaxy group. We use archival HIPASS and Australia Telescope Compact Array (ATCA) observations of this group to validate the new ASKAP data and the data reduction pipeline ASKAPsoft. We detect six galaxies in the neutral hydrogen (HI) 21-cm line, expanding the NGC 7162 group membership from four to seven galaxies. Two of the new detections are also the first HI detections of the dwarf galaxies, AM 2159-434 and GALEXASC J220338.65-431128.7, for which we have measured velocities of cz=2558cz=2558 and cz=2727cz=2727 km s−1^{-1}, respectively. We confirm that there is extended HI emission around NGC 7162 possibly due to past interactions in the group as indicated by the 40∘40^{\circ} offset between the kinematic and morphological major axes for NGC 7162A, and its HI richness. Taking advantage of the increased resolution (factor of ∼1.5\sim1.5) of the ASKAP data over archival ATCA observations, we fit a tilted ring model and use envelope tracing to determine the galaxies' rotation curves. Using these we estimate the dynamical masses and find, as expected, high dark matter fractions of fDM∼0.81−0.95f_{\mathrm{DM}}\sim0.81-0.95 for all group members. The ASKAP data are publicly available.Comment: 20 pages, 11 figures, accepted for publication in MNRA

    WALLABY early science – I. The NGC 7162 galaxy group

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    We present Widefield ASKAP L-band Legacy All-sky Blind Survey (WALLABY) early science results from the Australian Square Kilometre Array Pathfinder (ASKAP) observations of the NGC 7162 galaxy group. We use archival HIPASS and Australia Telescope Compact Array (ATCA) observations of this group to validate the new ASKAP data and the data reduction pipeline ASKAP soft. We detect six galaxies in the neutral hydrogen (H i) 21-cm line, expanding the NGC 7162 group membership from four to seven galaxies. Two of the new detections are also the first H i detections of the dwarf galaxies, AM 2159-434 and GALEXASC J220338.65-431128.7, for which we have measured velocities of cz = 2558 and cz = 2727 km s−1, respectively. We confirm that there is extended H i emission around NGC 7162 possibly due to past interactions in the group as indicated by the 40° offset between the kinematic and morphological major axes for NGC 7162A, and its H i richness. Taking advantage of the increased resolution (factor of ∼1.5) of the ASKAP data over archival ATCA observations, we fit a tilted ring model and use envelope tracing to determine the galaxies’ rotation curves. Using these we estimate the dynamical masses and find, as expected, high dark matter fractions of fDM ∼ 0.81−0.95 for all group members. The ASKAP data are publicly available.Publisher PDFPeer reviewe

    PETG: Applications in Modern Medicine

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    Polyethylene terephthalate glycol, PETG, is a miscible, transparent thermoplastic known to have strong tensile properties, high ductility, as well as resistance to heat and chemical insults. PETG may be manufactured in several ways, most notably 3D printing modalities. As such, PETG has emerged as a viable biomaterial for a variety of medical applications such as tissue engineering, dentistry, optometry, vascular health, cardiology, orthopedics, neurology, gynecology, and surgery. PETG also serves a valuable role in biomedical research and engineering by offering improvements in cell studies, drug carriers, and anti-bacterial measures. Further medical research and innovation utilizing PETG will better characterize its value as an inexpensive and versatile biomaterial

    Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis

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    Lipotoxicity is a key mechanism thought to be responsible for the progression of nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH). Noninvasive diagnosis of NASH is a major unmet clinical need, and we hypothesized that PUFA metabolites, in particular arachidonic acid (AA)-derived eicosanoids, in plasma would differentiate patients with NAFL from those with NASH. Therefore, we aimed to assess the differences in the plasma eicosanoid lipidomic profile between patients with biopsy-proven NAFL versus NASH versus normal controls without nonalcoholic fatty liver disease (NAFLD; based on MRI fat fraction <5%). We carried out a cross-sectional analysis of a prospective nested case-control study including 10 patients with biopsy-proven NAFL, 9 patients with biopsy-proven NASH, and 10 non-NAFLD MRI-phenotyped normal controls. We quantitatively compared plasma eicosanoid and other PUFA metabolite levels between NAFL versus NASH versus normal controls. Utilizing a uniquely well-characterized cohort, we demonstrated that plasma eicosanoid and other PUFA metabolite profiling can differentiate between NAFL and NASH. The top candidate as a single biomarker for differentiating NAFL from NASH was 11,12-dihydroxy-eicosatrienoic acid (11,12-diHETrE) with an area under the receiver operating characteristic curve (AUROC) of 1. In addition, we also found a panel including 13,14-dihydro-15-keto prostaglandin D(2) (dhk PGD2) and 20-carboxy arachidonic acid (20-COOH AA) that demonstrated an AUROC of 1. This proof-of-concept study provides early evidence that 11,12-diHETrE, dhk PGD2, and 20-COOH AA are the leading eicosanoid candidate biomarkers for the noninvasive diagnosis of NASH
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