1,535 research outputs found

    Preventing hung juries about therapy studies.

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    EARLY IMPACT MELTING AND SPACE EXPOSURE HISTORY OF THE PAT91501 LCHONDRITE

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    Collisions probably occurred frequently in the early history of the asteroid belt. Their effects, which should be recorded in meteorites, must have included heating and melting along with shock alteration of mineral textures. Some non-chondritic meteorite types e.g., eucrites and IIE and IAB irons - do indeed give evidence of extensive impact heating more than 3.4 Gyr ago. The ordinary chondrites, in contrast, show little evidence of early impact heating. The Ar-Ar and Rb-Sr ages of ordinary chondrites that experienced intense shock are for the most part relatively young, many less than 1.5 Gyr. The numerous L-chondrites with Ar- Ar ages clustering near 0.5 Gy are a well-known example. One of them, the 105-kg Chico Lchondrite, shows the effects of unusually intense heating. It is approximately 60% impact melt and likely formed as a dyke beneath a large crater when the L-chondrite parent body underwent a very large impact approximately 0.5 Gyr ago. In rare instances, older shock dates are indicated for ordinary chondrites. Dixon et al show early impact resetting of Ar-Ar ages of a few LL-chondrites including MIL 99301 at 4.23 0.03 Gyr, but in none of these stones did shock lead to extensive melting. As of 2003, searches for chondritic melts attributable to early shock had turned up only the Shaw L-chondrite, which has an Ar-Ar age of approximately 4.42 Gyr. PAT91501 is an 8.55-kg L-chondrite containing vesicles and metal-troilite nodules. It is a unique, near-total impact melt, unshocked, depleted in siderophile and chalcophile elements, and contains only approximately 10% relic chondritic material. The authors conclude that PAT91501 crystallized rapidly and from a much more homogeneous melt than did Shaw. They suggest that PAT resembles Chico and likely formed as an impact melt vein within an impact crater. To define the history of PAT, we have determined its Ar-39-Ar-40 age and measured several radioactive and stable nuclides produced during its space exposure to cosmic rays

    Space-Time Clustering and Correlations of Major Earthquakes

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    Earthquake occurrence in nature is thought to result from correlated elastic stresses, leading to clustering in space and time. We show that occurrence of major earthquakes in California correlates with time intervals when fluctuations in small earthquakes are suppressed relative to the long term average. We estimate a probability of less than 1% that this coincidence is due to random clustering.Comment: 5 pages, 3 figures. Submitted to PR

    Multiwavelength Observations of Massive Stellar Cluster Candidates in the Galaxy

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    The Galaxy appears to be richer in young, massive stellar clusters than previously known, due to advances in infrared surveys which have uncovered deeply embedded regions of star formation. Young, massive clusters can significantly impact the surrounding interstellar medium (ISM) and hence radio observations can also be an important tracer of their activity. Several hundred cluster candidates are now known by examining survey data. Here we report on multiwavelength observations of six of these candidates in the Galaxy. We carried out 4.9 and 8.5 GHz VLA observations of the radio emission associated with these clusters to obtain the physical characteristics of the surrounding gas, including the Lyman continuum photon flux and ionized gas mass. Spitzer Infrared Array Camera observations were also made of these regions, and provide details on the stellar population as well as the dust continuum and polycyclic aromatic hydrocarbon emission. When compared to the known young, massive clusters in the Galaxy, the six cluster candidates have less powerful Lyman ionizing fluxes and ionize less of the H II mass in the surrounding ISM. Therefore, these cluster candidates appear to be more consistent with intermediate-mass clusters (10^3-10^4 Msun).Comment: 39 pages, 20 figures. Accepted in the Astronomical Journal; to be published Fall 201

    Cognitive-Behavioral Group Therapy versus Phenelzine in Social Phobia: Long-Term Outcome

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    To evaluate the effects of maintenance treatment and durability of gains after treatment discontinuation, responders to either phenelzine (PZ) or cognitive-behavioral group therapy (CBGT) from an acute trial comparing these two treatments as well as pill placebo and a psychotherapy control (educational supportive group therapy) were enrolled into maintenance and treatment-free follow-up phases. Experimental design: Responders to an acute trial contrasting PZ and CBGT entered a six-month maintenance phase. Patients who continued to respond through the maintenance phase entered a six-month treatment-free phase. Patients receiving pill placebo or educational supportive group therapy in the acute trial did not enter the long-term study. Principal observations: PZ patients entered maintenance more improved than CBGT patients, and nonrelapsing PZ patients maintained their superior gains throughout the study. Relapse during maintenance did not differ between treatments. However, PZ patients showed a trend toward greater relapse during treatment-free follow-up. There was a greater relapse among patients with generalized social phobia with phenelzine. Conclusions: PZ and cognitive-behavioral group therapy may differ in their long-term effects. The superiority seen with PZ on some measures in the acute study persisted in patients who maintained their gains over the course of maintenance and treatment-free follow-up. However, CBGT may lead to a greater likelihood of maintaining response after treatment has terminated. Replication with larger samples is needed, as is a study of the acute and long-term efficacy of combined PZ and CBGT

    Genetic nomenclature for the H-2 complex of the mouse

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46730/1/251_2005_Article_BF01564058.pd
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