1,376 research outputs found
Optimal streaks in a Falkner-Skan boundary layer
This paper deals with the optimal streaky perturbations (which maximize the
perturbed energy growth) in a wedge flow boundary layer. These three
dimensional perturbations are governed by a system of linearized boundary layer
equations around the Falkner-Skan base flow. Based on an asymptotic analysis of
this system near the free stream and the leading edge singularity, we show that
for acute wedge semi-angle, all solutions converge after a streamwise transient
to a single streamwise-growing solution of the linearized equations, whose
initial condition near the leading edge is given by an eigenvalue problem first
formulated in this context by Tumin (2001). Such a solution may be regarded as
a streamwise evolving most unstable streaky mode, in analogy with the usual
eigenmodes in strictly parallel flows, and shows an approximate
self-similarity, which was partially known and is completed in this paper. An
important consequence of this result is that the optimization procedure based
on the adjoint equations heretofore used to define optimal streaks is not
necessary. Instead, a simple low-dimensional optimization process is proposed
and used to obtain optimal streaks. Comparison with previous results by Tumin
and Ashpis (2003) shows an excellent agreement. The unstable streaky mode
exhibits transient growth if the wedge semi-angle is smaller than a critical
value that is slightly larger than , and decays otherwise. Thus the
cases of right and obtuse wedge semi-angles exhibit less practical interest,
but they show a qualitatively different behavior, which is briefly described to
complete the analysis
Quantification of myeloperoxidase from human granulocytes as an inflammation marker by enzyme.linked immunosorbent assay
Anisotropic eddy-viscosity concept for strongly detached unsteady flows
The accurate prediction of the flow physics around bodies at high Reynolds number is a challenge in aerodynamics nowadays. In the context of turbulent flow modeling, recent advances like large eddy simulation (LES) and hybrid methods [detached eddy simulation (DES)] have considerably improved the physical relevance of the numerical simulation. However, the LES approach is still limited to the low-Reynolds-number range concerning wall flows. The unsteady Reynolds-averaged NavierâStokes (URANS) approach remains a widespread and robust methodology for complex flow computation, especially in the near-wall region. Complex statistical models like second-order closure schemes [differential Reynolds stress modeling (DRSM)] improve the prediction of these properties and can provide an efficient simulationofturbulent stresses. Fromacomputational pointofview, the main drawbacks of such approaches are a higher cost, especially in unsteady 3-D flows and above all, numerical instabilities
Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophages.
Multiple Imputation Ensembles (MIE) for dealing with missing data
Missing data is a significant issue in many real-world datasets, yet there are no robust methods for dealing with it appropriately. In this paper, we propose a robust approach to dealing with missing data in classification problems: Multiple Imputation Ensembles (MIE). Our method integrates two approaches: multiple imputation and ensemble methods and compares two types of ensembles: bagging and stacking. We also propose a robust experimental set-up using 20 benchmark datasets from the UCI machine learning repository. For each dataset, we introduce increasing amounts of data Missing Completely at Random. Firstly, we use a number of single/multiple imputation methods to recover the missing values and then ensemble a number of different classifiers built on the imputed data. We assess the quality of the imputation by using dissimilarity measures. We also evaluate the MIE performance by comparing classification accuracy on the complete and imputed data. Furthermore, we use the accuracy of simple imputation as a benchmark for comparison. We find that our proposed approach combining multiple imputation with ensemble techniques outperform others, particularly as missing data increases
- âŠ