3 research outputs found
Single-Center Experience With the Bare p48MW Low-Profile Flow Diverter and Its Hydrophilically Covered Version for Treatment of Bifurcation Aneurysms in Distal Segments of the Anterior and Posterior Circulation
Background and Purpose: Flow diversion has profoundly changed the way aneurysms
are treated. However, it conventionally requires dual antiplatelet medication and has yet
been considered off-label use in the posterior circulation or within peripheral vessels of the
anterior circulation. Here, we report our experience with the p48MW/p48MW hydrophilic
coating (HPC) in the anterior and posterior circulation. This novel low-profile flow diverter
is specifically designed for treatment of small peripheral vessels, and the p48MW HPC
has an anti-thrombotic polymer coating, which allows application of a single antiplatelet
function medication in conditions that expectably require further surgery.
Materials and Methods: Thirty-two patients were prospectively included. Twenty-six
treatments were performed with one flow diverter, four required two overlapping flow
diverters, one case demanded three overlapping flow diverters, and in one case,
extensive dissecting aneurysm telescoping with eight flow diverters was necessary.
Twenty-two complex bifurcation aneurysms were treated. Three months’ follow-up was
available for 14 patients.
Results: Deployment was uneventful in all cases. In four cases, undersizing was
unavoidable and resulted in significant shortening of the flow diverter, which demanded
implantation of further flow diverters to sufficiently treat the target aneurysm. Three
flow diverters required balloon angioplasty for optimal wall approximation. All parent
vessels remained patent. Available 3-month follow-up studies showed decreased influx
or delayed washout in all aneurysms; none was occluded completely. There were no
device-related clinical complications.
Conclusions: Implantation of the p48MW/p48MW HPC is safe and effective for
treatment of distally located cerebral aneurysms. Considering the reported rates of
ischemic complications associated with flow diversion of complex bifurcation aneurysms,
the p48MW/p48MW HPC potentially provides increased safety for complex bifurcation
aneurysms in the anterior and posterior circulation
Single-Center Experience With the Bare p48MW Low-Profile Flow Diverter and Its Hydrophilically Covered Version for Treatment of Bifurcation Aneurysms in Distal Segments of the Anterior and Posterior Circulation
Background and Purpose: Flow diversion has profoundly changed the way aneurysms
are treated. However, it conventionally requires dual antiplatelet medication and has yet
been considered off-label use in the posterior circulation or within peripheral vessels of the
anterior circulation. Here, we report our experience with the p48MW/p48MW hydrophilic
coating (HPC) in the anterior and posterior circulation. This novel low-profile flow diverter
is specifically designed for treatment of small peripheral vessels, and the p48MW HPC
has an anti-thrombotic polymer coating, which allows application of a single antiplatelet
function medication in conditions that expectably require further surgery.
Materials and Methods: Thirty-two patients were prospectively included. Twenty-six
treatments were performed with one flow diverter, four required two overlapping flow
diverters, one case demanded three overlapping flow diverters, and in one case,
extensive dissecting aneurysm telescoping with eight flow diverters was necessary.
Twenty-two complex bifurcation aneurysms were treated. Three months’ follow-up was
available for 14 patients.
Results: Deployment was uneventful in all cases. In four cases, undersizing was
unavoidable and resulted in significant shortening of the flow diverter, which demanded
implantation of further flow diverters to sufficiently treat the target aneurysm. Three
flow diverters required balloon angioplasty for optimal wall approximation. All parent
vessels remained patent. Available 3-month follow-up studies showed decreased influx
or delayed washout in all aneurysms; none was occluded completely. There were no
device-related clinical complications.
Conclusions: Implantation of the p48MW/p48MW HPC is safe and effective for
treatment of distally located cerebral aneurysms. Considering the reported rates of
ischemic complications associated with flow diversion of complex bifurcation aneurysms,
the p48MW/p48MW HPC potentially provides increased safety for complex bifurcation
aneurysms in the anterior and posterior circulation
Single-Center Experience With the Bare p48MW Low-Profile Flow Diverter and Its Hydrophilically Covered Version for Treatment of Bifurcation Aneurysms in Distal Segments of the Anterior and Posterior Circulation
Background and Purpose: Flow diversion has profoundly changed the way aneurysms
are treated. However, it conventionally requires dual antiplatelet medication and has yet
been considered off-label use in the posterior circulation or within peripheral vessels of the
anterior circulation. Here, we report our experience with the p48MW/p48MW hydrophilic
coating (HPC) in the anterior and posterior circulation. This novel low-profile flow diverter
is specifically designed for treatment of small peripheral vessels, and the p48MW HPC
has an anti-thrombotic polymer coating, which allows application of a single antiplatelet
function medication in conditions that expectably require further surgery.
Materials and Methods: Thirty-two patients were prospectively included. Twenty-six
treatments were performed with one flow diverter, four required two overlapping flow
diverters, one case demanded three overlapping flow diverters, and in one case,
extensive dissecting aneurysm telescoping with eight flow diverters was necessary.
Twenty-two complex bifurcation aneurysms were treated. Three months’ follow-up was
available for 14 patients.
Results: Deployment was uneventful in all cases. In four cases, undersizing was
unavoidable and resulted in significant shortening of the flow diverter, which demanded
implantation of further flow diverters to sufficiently treat the target aneurysm. Three
flow diverters required balloon angioplasty for optimal wall approximation. All parent
vessels remained patent. Available 3-month follow-up studies showed decreased influx
or delayed washout in all aneurysms; none was occluded completely. There were no
device-related clinical complications.
Conclusions: Implantation of the p48MW/p48MW HPC is safe and effective for
treatment of distally located cerebral aneurysms. Considering the reported rates of
ischemic complications associated with flow diversion of complex bifurcation aneurysms,
the p48MW/p48MW HPC potentially provides increased safety for complex bifurcation
aneurysms in the anterior and posterior circulation