2,059 research outputs found
Visual argumentation in an Al Gore keynote presentation on climate change
The use of digital presentation tools such as PowerPoint is ubiquitous; however we still do not know much about the persuasiveness of these programs. Examining the use of visual analogy and visual chronology, in particular, this paper explores the use of visual argumentation in a Keynote presentation by Al Gore. It illustrates how images function as an integrated part of Gores reasoning
How to optimize the use of diuretics in patients with heart failure?
Considering the pathophysiology and clinical presentation of heart failure, using diuretics or drugs with diuretic properties is indispensable for adequate management of heart failure patients. However, in clinical practice, fluid expansion is often undiagnosed, and diuretic therapy is not always adequately titrated. Today, several drug classes with diuretic properties are available in addition to classical thiazides, thiazide-like, and loop diuretics. The purpose of this short review is to discuss different ways to optimize diuretic therapy using currently available drugs. Several approaches are considered, including a combination of diuretics to obtain a sequential nephron blockade, use of a drug combining a blocker of the renin-angiotensin system (RAS) and an inhibitor of the metabolism of natriuretic peptides (ARNI), prescription of potassium binders to maintain and up-titrate RAS blockers and mineralocorticoid antagonists, and finally use of inhibitors of renal reabsorption of glucose through the sodium-glucose cotransporter 2 system. Optimal use of these various drug classes should improve the quality of life and reduce the need for hospital admissions and mortality in heart failure patients
Vibrational excitation of diatomic molecular ions in strong-field ionization of diatomic molecules
A model based on the strong-field and Born-Oppenheimer approximations
qualitatively describes the distribution over vibrational states formed in a
diatomic molecular ion following ionization of the neutral molecule by intense
laser pulses. Good agreement is found with a recent experiment [X. Urbain et
al., Phys. Rev. Lett. 92, 163004 (2004)]. In particular, the observed deviation
from a Franck-Condon-like distribution is reproduced. Additionally, we
demonstrate control of the vibrational distribution by a variation of the peak
intensity or a change of frequency of the laser pulse.Comment: 4 pages, 4 figure
Complete genome sequence of Desulfocapsa sulfexigens, a marine deltaproteobacterium specialized in disproportionating inorganic sulfur compounds
Desulfocapsa sulfexigens SB164P1 (DSM 10523) belongs to the deltaproteobacterial family Desulfobulbaceae and is one of two validly described members of its genus. This strain was selected for genome sequencing, because it is the first marine bacterium reported to thrive on the disproportionation of elemental sulfur, a process with a unresolved enzymatic pathway in which elemental sulfur serves both as electron donor and electron acceptor. Furthermore, in contrast to its phylogenetically closest relatives, which are dissimilatory sulfate-reducers, D. sulfexigens is unable to grow by sulfate reduction and appears metabolically specialized in growing by disproportionating elemental sulfur, sulfite or thiosulfate with CO2 as the sole carbon source. The genome of D. sulfexigens contains the set of genes that is required for nitrogen fixation. In an acetylene assay it could be shown that the strain reduces acetylene to ethylene, which is indicative for N-fixation. The circular chromosome of D. sulfexigens SB164P1 comprises 3,986,761 bp and harbors 3,551 protein-coding genes of which 78% have a predicted function based on auto-annotation. The chromosome furthermore encodes 46 tRNA genes and 3 rRNA operons
Solving the m-mixing problem for the three-dimensional time-dependent Schr\"{o}dinger equation by rotations: application to strong-field ionization of H2+
We present a very efficient technique for solving the three-dimensional
time-dependent Schrodinger equation. Our method is applicable to a wide range
of problems where a fullly three-dimensional solution is required, i.e., to
cases where no symmetries exist that reduce the dimensionally of the problem.
Examples include arbitrarily oriented molecules in external fields and atoms
interacting with elliptically polarized light. We demonstrate that even in such
cases, the three-dimensional problem can be decomposed exactly into two
two-dimensional problems at the cost of introducing a trivial rotation
transformation. We supplement the theoretical framework with numerical results
on strong-field ionization of arbitrarily oriented H2+ molecules.Comment: 5 pages, 4 figure
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