BioGlue® coronary embolism during open heart surgery

AbstractIn cases of iatrogenic coronary embolism during cardiac surgery or percutaneous coronary intervention, small air bubbles or foreign bodies are directly injected, which usually result in serious adverse events if not treated promptly. We herein describe the case of a patient who developed acute myocardial infarction resulting in shock due to BioGlue® (CryoLife, Atlanta, GA, USA)-induced coronary embolism during the surgical repair of aortic dissection and was treated for retrieval of the material using a thrombectomy catheter.<Learning objective: Coronary embolism caused by surgical adhesives is a rare but potentially life-threatening complication. It is important for surgeons to promptly recognize and treat this serious condition in consultation with cardiologists.

NMR study in the superconducting silicon clathrate compound NaxBaySi46

29Si, 23Na, 137Ba, and 135Ba NMR experiments were carried out in the superconducting silicon clathrate compound NaxBaySi46 to study the electronic states above the superconducting transition temperature. We observed three distinct 29Si signals with different Knight shift (2036, 862, and 720 ppm at 90 K with a small temperature dependence of ∼10%), which were ascribed to inequivalent Si sites in the Si46 structure. The results indicate that the conduction-electron spin and/or charge density is strongly site-dependent. At all the atomic sites, the Korringa relation in NMR relaxation was observed, indicative of metallic electronic structure with moderate electronic correlation. The Na and Ba atoms are partially ionized in NaxBaySi46, which shows the noticeable difference from the system of alkali-metal-doped fullerides. The comparison with band calculations is discussed

Novel anti‐tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102710/1/cas12315.pd

No association between CEL-HYB hybrid allele and chronic pancreatitis in Asian populations

International audienceA hybrid allele between the carboxyl ester lipase gene (CEL) and its pseudogene, CELP (called CEL–HYB), generated by non-allelic homologous recombination between CEL intron 10 and CELP intron 10′, was found to increase susceptibility to chronic pancreatitis in a case–control study of patients of European ancestry. We attempted to replicate this finding in 3 independent cohorts from China, Japan, and India, but failed to detect the CEL–HYB allele in any of these populations. The CEL–HYB allele might therefore be an ethnic-specific risk factor for chronic pancreatitis. An alternative hybrid allele (CEL–HYB2) was identified in all 3 Asian populations (1.7% combined carrier frequency), but was not associated with chronic pancreatitis

The Japanese Clinical Practice Guideline for acute kidney injury 2016

Acute kidney injury (AKI) is a syndrome which has a broad range of etiologic factors depending on different clinical settings. Because AKI has significant impacts on prognosis in any clinical settings, early detection and intervention are necessary to improve the outcomes of AKI patients. This clinical guideline for AKI was developed by a multidisciplinary approach with nephrology, intensive care medicine, blood purification, and pediatrics. Of note, clinical practice for AKI management which was widely performed in Japan was also evaluated with comprehensive literature search