Group theoretical studies of the periodic chart and of configuration mixing in the ground state of helium

Recently Wulfman found great merit in Barut\u27s idea on atomic super-multiplets, and he introduced the concept of the generalized Hamiltonian that is the Hamiltonian of all atoms. 24 Investigating the Schrodinger equation with this generalized Hamiltonian, it should be possible to relate the properties of different atoms and find the structure of the periodic chart from fundamental principles of dynamics and group theory. One can can use the same kinds of methods for relating the properties of different states of a single hydrogen atom with the aid of the degeneracy group S0 (4) and dynamical group SO (4, 2). These groups represent the symmetries of the time-independent and time-dependent Schrodinger equations with ordinary Hamiltonian.(25,26) The idea then is to apply these methods to the system defined by a generalized Hamiltonian. In chapter II of this thesis, we will consider the classification of chemical elements, in the light of the concept of the generalized Hamiltonian. We will make a group theoretical classification based on the characteristics of the outermost electrons in the central-field model of atomic ground states. We conclude that the classification group may be SO (p,q) with p+q≧, p ≧4. In chapter III of this thesis, we will review Wulfman\u27s work briefly and consider an application of his idea to the ground state of helium making use of the group SO (4,1) xSO (4,1). We arrive at the conclusion that we can obtain physically significant configuration mixing using SO (4,1) xSO (4,1) or SO (4,2) xSO (4,2) in a manner analogous to the way in which SO (4) xSO (4) is used to determine configuration mixing in doubly excited states of helium-like systems

Novel Bioactivation Pathway of Benzbromarone Mediated by Cytochrome P450

ABSTRACT Benzbromarone (BBR) is a hepatotoxic drug, but the detailed mechanism of its toxicity remains unknown. We identified 2,6-dibromohydroquinone (DBH) and mono-debrominated catechol (2-ethyl-3-(3-bromo-4,5-dihydroxybenzoyl)benzofuran; CAT) as novel metabolites of BBR in rat and human liver microsomal systems by comparison with chemically synthesized authentic compounds, and we also elucidated that DBH is formed by cytochrome P450 2C9 and that CAT is formed mainly by CYP1A1, 2D6, 2E1, and 3A4. Furthermore, CAT, DBH, and the oxidized form of DBH are highly cytotoxic in HepG2 compared with BBR. Taken together, our data demonstrate that DBH, a novel reactive metabolite, may be relevant to BBR-induced hepatotoxicity

digital design and wooden architecture for arte sella land art park

Digital design is increasingly sinking the construction sector, shaping and validating architecture according to various criteria and introducing the wood industry to the 4.0 approach. Within the study entitled "Architecture at Arte Sella", parametric design, structural validations and CNC procedures are exploited to help define, control and assess several architectural woodworks, created with famous designers. This contribution describes the design and construction experiences of Atsushi Kitagawara (2017) and Kengo Kuma (2018–2019), the two masterpieces installed in the land art park of Arte Sella (Trento, Italy) and developed, thanks to the Politecnico di Milano team, from design to mock-ups, testing and construction

Kinetic energy bounds for particles confined in spherically-symmetric traps with non-standard dimensions

The kinetic energy of non-relativistic single-particle systems with arbitrary D-dimensional central potentials is found to be bounded from below by means of the orbital hyperangular quantum number, the dimensionality and some radial and logarithmic expectation values of the form langrkrang and langrk (ln r)mrang. Beyond the intrinsic physico-mathematical interest of this problem, we want to contribute to the current development of the theory of independent particles confined in spherically symmetric traps with non-standard dimensions. The latter has been motivated by the recent experimental achievements of the evaporative cooling of dilute (i.e. almost non-interacting) fermions in magnetic traps.We are very grateful for partial support from Junta de Andalucía (under the grants FQM-0207 and FQM-481), Ministerio de Educación y Ciencia (under the project FIS2005-00973), and the European Research Network NeCCA (under the project INTAS-03-51-6637). RGF acknowledges the support of Junta de Andalucía under the program of Retorno de Investigadores a Centros de Investigación Andaluces, and PSM the support of Ministerio de Educación y Ciencia under the program FPU

Group theoretical studies of the periodic chart and of configuration mixing in the ground state of helium

Recently Wulfman found great merit in Barut\u27s idea on atomic super-multiplets, and he introduced the concept of the generalized Hamiltonian that is the Hamiltonian of all atoms. 24 Investigating the Schrodinger equation with this generalized Hamiltonian, it should be possible to relate the properties of different atoms and find the structure of the periodic chart from fundamental principles of dynamics and group theory. One can can use the same kinds of methods for relating the properties of different states of a single hydrogen atom with the aid of the degeneracy group S0 (4) and dynamical group SO (4, 2). These groups represent the symmetries of the time-independent and time-dependent Schrodinger equations with ordinary Hamiltonian.(25,26) The idea then is to apply these methods to the system defined by a generalized Hamiltonian. In chapter II of this thesis, we will consider the classification of chemical elements, in the light of the concept of the generalized Hamiltonian. We will make a group theoretical classification based on the characteristics of the outermost electrons in the central-field model of atomic ground states. We conclude that the classification group may be SO (p,q) with p+q≧, p ≧4. In chapter III of this thesis, we will review Wulfman\u27s work briefly and consider an application of his idea to the ground state of helium making use of the group SO (4,1) xSO (4,1). We arrive at the conclusion that we can obtain physically significant configuration mixing using SO (4,1) xSO (4,1) or SO (4,2) xSO (4,2) in a manner analogous to the way in which SO (4) xSO (4) is used to determine configuration mixing in doubly excited states of helium-like systems