HYDROGEN BONDING IN betabeta-NITRO ALCOHOLS. III. PYRIDINE COMPLEXES

BETA -Nitro alcohols form stable 1:1 complexes with pyridine, examples of which were prepared. In solvents such as dichloromethane and carbon tetrachloride the complexes partially dissociate into their components. The dissociation constants for the equilibria were determined by infrared methods and may be used as a measure of the strength of the complex hydrogen bond. The dissociation constants decrease with increasing number of BETA -nitro groups. Some reactions of the pyridine complexes are described. (auth

Quantum picturalism for topological cluster-state computing

Topological quantum computing is a way of allowing precise quantum computations to run on noisy and imperfect hardware. One implementation uses surface codes created by forming defects in a highly-entangled cluster state. Such a method of computing is a leading candidate for large-scale quantum computing. However, there has been a lack of sufficiently powerful high-level languages to describe computing in this form without resorting to single-qubit operations, which quickly become prohibitively complex as the system size increases. In this paper we apply the category-theoretic work of Abramsky and Coecke to the topological cluster-state model of quantum computing to give a high-level graphical language that enables direct translation between quantum processes and physical patterns of measurement in a computer - a "compiler language". We give the equivalence between the graphical and topological information flows, and show the applicable rewrite algebra for this computing model. We show that this gives us a native graphical language for the design and analysis of topological quantum algorithms, and finish by discussing the possibilities for automating this process on a large scale.Comment: 18 pages, 21 figures. Published in New J. Phys. special issue on topological quantum computin

The GHZ/W-calculus contains rational arithmetic

Graphical calculi for representing interacting quantum systems serve a number of purposes: compositionally, intuitive graphical reasoning, and a logical underpinning for automation. The power of these calculi stems from the fact that they embody generalized symmetries of the structure of quantum operations, which, for example, stretch well beyond the Choi-Jamiolkowski isomorphism. One such calculus takes the GHZ and W states as its basic generators. Here we show that this language allows one to encode standard rational calculus, with the GHZ state as multiplication, the W state as addition, the Pauli X gate as multiplicative inversion, and the Pauli Z gate as additive inversion.Comment: In Proceedings HPC 2010, arXiv:1103.226

Nonequilibrium wetting of finite samples

As a canonical model for wetting far from thermal equilibrium we study a Kardar-Parisi-Zhang interface growing on top of a hard-core substrate. Depending on the average growth velocity the model exhibits a non-equilibrium wetting transition which is characterized by an additional surface critical exponent theta. Simulating the single-step model in one spatial dimension we provide accurate numerical estimates for theta and investigate the distribution of contact points between the substrate and the interface as a function of time. Moreover, we study the influence of finite-size effects, in particular the time needed until a finite substrate is completely covered by the wetting layer for the first time.Comment: 17 pages, 8 figures, revisio

Scholarship and security policy: a review of recent literature

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68058/2/10.1177_002200275900300408.pd

Non-equilibrium Phase Transitions with Long-Range Interactions

This review article gives an overview of recent progress in the field of non-equilibrium phase transitions into absorbing states with long-range interactions. It focuses on two possible types of long-range interactions. The first one is to replace nearest-neighbor couplings by unrestricted Levy flights with a power-law distribution P(r) ~ r^(-d-sigma) controlled by an exponent sigma. Similarly, the temporal evolution can be modified by introducing waiting times Dt between subsequent moves which are distributed algebraically as P(Dt)~ (Dt)^(-1-kappa). It turns out that such systems with Levy-distributed long-range interactions still exhibit a continuous phase transition with critical exponents varying continuously with sigma and/or kappa in certain ranges of the parameter space. In a field-theoretical framework such algebraically distributed long-range interactions can be accounted for by replacing the differential operators nabla^2 and d/dt with fractional derivatives nabla^sigma and (d/dt)^kappa. As another possibility, one may introduce algebraically decaying long-range interactions which cannot exceed the actual distance to the nearest particle. Such interactions are motivated by studies of non-equilibrium growth processes and may be interpreted as Levy flights cut off at the actual distance to the nearest particle. In the continuum limit such truncated Levy flights can be described to leading order by terms involving fractional powers of the density field while the differential operators remain short-ranged.Comment: LaTeX, 39 pages, 13 figures, minor revision

Cost-Effectiveness of Newborn Circumcision in Reducing Lifetime HIV Risk among U.S. Males

BACKGROUND: HIV incidence was substantially lower among circumcised versus uncircumcised heterosexual African men in three clinical trials. Based on those findings, we modeled the potential effect of newborn male circumcision on a U.S. male's lifetime risk of HIV, including associated costs and quality-adjusted life-years saved. METHODOLOGY/PRINCIPAL FINDINGS: Given published estimates of U.S. males' lifetime HIV risk, we calculated the fraction of lifetime risk attributable to heterosexual behavior from 2005-2006 HIV surveillance data. We assumed 60% efficacy of circumcision in reducing heterosexually-acquired HIV over a lifetime, and varied efficacy in sensitivity analyses. We calculated differences in lifetime HIV risk, expected HIV treatment costs and quality-adjusted life years (QALYs) among circumcised versus uncircumcised males. The main outcome measure was cost per HIV-related QALY saved. Circumcision reduced the lifetime HIV risk among all males by 15.7% in the base case analysis, ranging from 7.9% for white males to 20.9% for black males. Newborn circumcision was a cost-saving HIV prevention intervention for all, black and Hispanic males. The net cost of newborn circumcision per QALY saved was $87,792 for white males. Results were most sensitive to the discount rate, and circumcision efficacy and cost. CONCLUSIONS/SIGNIFICANCE: Newborn circumcision resulted in lower expected HIV-related treatment costs and a slight increase in QALYs. It reduced the 1.87% lifetime risk of HIV among all males by about 16%. The effect varied substantially by race and ethnicity. Racial and ethnic groups who could benefit the most from circumcision may have least access to it due to insurance coverage and state Medicaid policies, and these financial barriers should be addressed. More data on the long-term protective effect of circumcision on heterosexual males as well as on its efficacy in preventing HIV among MSM would be useful

320 GHz On-Chip Circularly-Polarized Antenna Array Realized with 0.13 μm BiCMOS Technology

A 320 GHz on-chip circularly-polarized (CP) antenna array that has been facilitated with 0.13 μm SiGe BiCMOS technology is presented. It is the first designed and prototyped THz-band on-chip antenna array with circular polarization and high directivity. The antenna is realized by designing a 4 \times 4 microstrip-fed CP patch antenna array inside the silicon dioxide layer on top of a silicon base. A sequential phase rotation scheme is applied to the four 2 \times 2 subarrays to achieve wide axial ratio (AR) bandwidth (8.7 GHz). The antenna array was successfully prototyped in a 3.6\times 3.6 mm2 area on a silicon wafer. Consequently, it easily combined with other integrated circuit (IC) components. The developed THz on-chip CP antenna is highly desired for the emerging ultra-high speed wireless applications

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of species-specific genes. Initial comparative genome analyses of the human malaria parasite Plasmodium falciparum and rodent malaria parasites (RMPs) revealed a core set of 4,500 Plasmodium orthologs located in the highly syntenic central regions of the chromosomes that sharply defined the boundaries of the variable subtelomeric regions. We used composite RMP contigs, based on partial DNA sequences of three RMPs, to generate a whole-genome synteny map of P. falciparum and the RMPs. The core regions of the 14 chromosomes of P. falciparum and the RMPs are organized in 36 synteny blocks, representing groups of genes that have been stably inherited since these malaria species diverged, but whose relative organization has altered as a result of a predicted minimum of 15 recombination events. P. falciparum-specific genes and gene families are found in the variable subtelomeric regions (575 genes), at synteny breakpoints (42 genes), and as intrasyntenic indels (126 genes). Of the 168 non-subtelomeric P. falciparum genes, including two newly discovered gene families, 68% are predicted to be exported to the surface of the blood stage parasite or infected erythrocyte. Chromosomal rearrangements are implicated in the generation and dispersal of P. falciparum-specific gene families, including one encoding receptor-associated protein kinases. The data show that both synteny breakpoints and intrasyntenic indels can be foci for species-specific genes with a predicted role in host-parasite interactions and suggest that, besides rearrangements in the subtelomeric regions, chromosomal rearrangements may also be involved in the generation of species-specific gene families. A majority of these genes are expressed in blood stages, suggesting that the vertebrate host exerts a greater selective pressure than the mosquito vector, resulting in the acquisition of diversity

Pyrolysis of medium-density fiberboard: optimized search for kinetics scheme and parameters via a genetic algorithm driven by Kissinger's method

The pyrolysis kinetics of charring materials plays an important role in understanding material combustions especially for construction materials with complex degradation chemistry. Thermogravimetric analysis (TGA) is frequently used to study the heterogeneous kinetics of solid fuels; however, there is no agreed method to determine the pyrolysis scheme and kinetic parameters for charring polymers with multiple components and competing reaction pathways. This study develops a new technique to estimate the possible numbers of species and sub-reactions in pyrolysis by analyzing the second derivatives of thermogravimetry (DDTG) curves. The pyrolysis of a medium-density fiberboard (MDF) in nitrogen is studied in detail, and the DDTG curves are used to locate the temperature of the peak mass-loss rate for each sub-reaction. Then, on the basis of the TG data under multiple heating rates, Kissinger’s method is used to quickly find the possible range of values of the kinetic parameters (<i>A</i> and <i>E</i>). These ranges are used to accelerate the optimization of the inverse problem using a genetic algorithm (GA) for the kinetic and stoichiometric parameters. The proposed method and kinetic scheme found are shown to match the experimental data and are able to predict accurately results at different heating rates better than Kissinger’s method. Moreover, the search method (K–K method) is highly efficient, faster than the regular GA search alone. Modeling results show that, as the TG data available increase, the interdependence among kinetic parameters becomes weak and the accuracy of the first-order model declines. Furthermore, conducting TG experiment under multiple heating rates is found to be crucial in obtaining good kinetic parameters