893 research outputs found

    Knowledge management challenges in corporate venturing and technological capability building through radical innovations

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    radical innovation, technological capability, corporate venturing, knowledge management

    Broadening Accessibility Through Special Interests: A New Approach for Software Customization

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    Individuals diagnosed with autism spectrum disorder (ASD) often fixate on narrow, restricted interests. These interests can be highly motivating, but they can also create attentional myopia, preventing individuals from pursuing a broad range of activities. Interestingly, researchers have found that preferred interests can be used to help individuals with ASD branch out and participate in educational, therapeutic, or social situations they might otherwise shun. When interventions are modified, such that an individual’s interest is properly represented, task adherence and performance can increase. While this strategy has seen success in the research literature, it is difficult to implement on a large scale and therefore has not been widely adopted. This paper describes a software approach designed to solve this problem. The approach facilitates customization, allowing users to easily embed images of almost any special interest into computer-based interventions. Specifically, we describe an algorithm that will: (1) retrieve any image from the Google image database; (2) strip it of its background; and (3) embed it seamlessly into Flash-based computer programs. To evaluate our algorithm, we employed it in a naturalistic setting with eleven individuals (nine diagnosed with ASD and two diagnosed with other developmental disorders). We also tested its ability to retrieve and process examples of preferred interests previously reported in the ASD literature. The results indicate that our method was an easy and efficient way for users to customize our software programs. While we believe this model is uniquely suited for individuals with ASD, we also foresee this approach being useful for anyone that might like a quick and simple way to personalize software programs.Things That Think ConsortiumBank of Americ

    Single electron-phonon interaction in a suspended quantum dot phonon cavity

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    An electron-phonon cavity consisting of a quantum dot embedded in a free-standing GaAs/AlGaAs membrane is characterized in Coulomb blockade measurements at low temperatures. We find a complete suppression of single electron tunneling around zero bias leading to the formation of an energy gap in the transport spectrum. The observed effect is induced by the excitation of a localized phonon mode confined in the cavity. This phonon blockade of transport is lifted at magnetic fields where higher electronic states with nonzero angular momentum are brought into resonance with the phonon energy.Comment: 4 pages, 4 figure

    Electron impact double ionization of helium from classical trajectory calculations

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    With a recently proposed quasiclassical ansatz [Geyer and Rost, J. Phys. B 35 (2002) 1479] it is possible to perform classical trajectory ionization calculations on many electron targets. The autoionization of the target is prevented by a M\o{}ller type backward--forward propagation scheme and allows to consider all interactions between all particles without additional stabilization. The application of the quasiclassical ansatz for helium targets is explained and total and partially differential cross sections for electron impact double ionization are calculated. In the high energy regime the classical description fails to describe the dominant TS1 process, which leads to big deviations, whereas for low energies the total cross section is reproduced well. Differential cross sections calculated at 250 eV await their experimental confirmation.Comment: LaTeX, 22 pages, 10 figures, submitted to J. Phys.

    Semi-Classical Description of Antiproton Capture on Atomic Helium

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    A semi-classical, many-body atomic model incorporating a momentum-dependent Heisenberg core to stabilize atomic electrons is used to study antiproton capture on Helium. Details of the antiproton collisions leading to eventual capture are presented, including the energy and angular momentum states of incident antiprotons which result in capture via single or double electron ionization, i.e. into [He++pˉ^{++}\,\bar p or He+pˉ^{+}\,\bar p], and the distribution of energy and angular momentum states following the Auger cascade. These final states are discussed in light of recently reported, anomalously long-lived antiproton states observed in liquid He.Comment: 15 pages, 9 figures may be obtained from authors, Revte

    Depression and Anxiety Correlate Differently with Salivary Free Cortisol in the Morning in Patients with Functional Somatic Syndrome

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    Patients presenting with functional somatic syndrome (FSS) are common, and the symptoms are persistent and difficult to treat for doctors and costly for society. The aim of this study was to clarify the common pathophysiology of FSS, especially the relationship between hypothalamic-pituitary-adrenal (HPA) axis function and psychological characteristics of patients with FSS. The subjects were 45 patients with FSS and 29 healthy controls. Salivary free cortisol was measured in the morning, and psychological tests examining depression, anxiety and quality of life (QOL) were performed on the same day. In patients with FSS, depressive scores showed a significant negative correlation with salivary free cortisol in the morning, although in healthy controls, cortisol showed a significant positive correlation with depressive scores. In addition, the correlation between other psychological test scores and cortisol secretion in patients with FSS contrasted with that of controls. The relationship between cortisol and depression, anxiety or QOL, suggests that the HPA axis of patients with FSS is dysfunctional and does not function properly when patients with FSS are under stress. This dysfunction may explain the pathology of medically unexplained persistent symptoms of patients with FSS
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