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A Nyström method for a class of integral equations on the real line with applications to scattering by diffraction gratings and rough surfaces
We propose a Nystršom/product integration method for a class of second kind integral equations on the real line which arise in problems of two-dimensional scalar and elastic wave scattering by unbounded surfaces. Stability and convergence of the method is established with convergence rates dependent on the smoothness of components of the kernel. The method is applied to the problem of acoustic scattering by a sound soft one-dimensional surface which is the graph of a function f, and superalgebraic convergence is established in the case when f is inïŹnitely smooth. Numerical results are presented illustrating this behavior for the case when f is periodic (the diïŹraction grating case). The Nystršom method for this problem is stable and convergent uniformly with respect to the period of the grating, in contrast to standard integral equation methods for diïŹraction gratings
which fail at a countable set of grating periods
Disentangling performance-monitoring signals encoded in feedback-related EEG dynamics
The feedback-related negativity (FRN) is a well-established electrophysiological correlate of feedback-processing. However, there is still an ongoing debate whether the FRN is driven by negative or positive reward prediction errors (RPE), valence of feedback, or mere surprise. Our study disentangles independent contributions of valence, surprise, and RPE on the feedback-related neuronal signal including the FRN and P3 components using the statistical power of a sample of N = 992 healthy individuals. The participants performed a modified time-estimation task, while EEG from 64 scalp electrodes was recorded. Our results show that valence coding is present during the FRN with larger amplitudes for negative feedback. The FRN is further modulated by surprise in a valence-dependent way being more positive-going for surprising positive outcomes. The P3 was strongly driven by both global and local surprise, with larger amplitudes for unexpected feedback and local deviants. Behavioral adaptations after feedback and FRN just show small associations. Results support the theory of the FRN as a representation of a signed RPE. Additionally, our data indicates that surprising positive feedback enhances the EEG response in the time window of the P3. These results corroborate previous findings linking the P3 to the evaluation of PEs in decision making and learning tasks
Activation dependent clustering of the erbB2 receptor tyrosine kinase detected by scanning near-field optical microscopy
ErbB2 (HER2, Neu), a member of the epidermal growth factor (EGF) receptor tyrosine kinase family, is often overexpressed in breast cancer and other malignancies, ErbB2 homodimerizes but also presents as a common auxiliary subunit of the EGF and heregulin receptors (erbB1 or EGFR; and erbB3-4, respectively), with which it heteroassociates, ErbB2 is generally regarded as an orphan (ligand-less) receptor with a very potent kinase domain activated either via its associated partners or constitutively as a consequence of discrete mutations. It follows that the extent and regulation of its cell surface interactions are of central importance. We have studied the large-scale association pattern of erbB2 in quiescent and activated cells labeled with fluorescent anti-erbB2 monoclonal antibodies using scanning near-field optical microscopy (SNOM), ErbB2 was found to be concentrated in irregular membrane patches with a mean diameter of approx. 0.5 mu m in nonactivated SKBR3 and MDA453 human breast tumor cells. The average number of erbB2 proteins in a single cluster on nonactivated SKBR3 cells was about 10(3). Activation of SKBR3 cells with EGF, heregulin as well as a partially agonistic anti-erbB2 monoclonal antibody led to an increase in the mean cluster diameter to 0.6-0.9 mu m, irrespective of the ligand, The EGF-induced increase in the erbB2 cluster size was inhibited by the EGFR-specific tyrosine kinase inhibitor PD153035, The average size of erbB2 clusters on the erbB2-transfected line of CHO cells (CB2) was similar to that of activated SKBR3 cells, a finding correlated with the increased base-line tyrosine phosphorylation of erbB2 in cells expressing only erbB2, We conclude that an increase in cluster size may constitute a general phenomenon in the activation of erbB2
The equivalence of fluctuation scale dependence and autocorrelations
We define optimal per-particle fluctuation and correlation measures, relate
fluctuations and correlations through an integral equation and show how to
invert that equation to obtain precise autocorrelations from fluctuation scale
dependence. We test the precision of the inversion with Monte Carlo data and
compare autocorrelations to conditional distributions conventionally used to
study high- jet structure.Comment: 10 pages, 9 figures, proceedings, MIT workshop on correlations and
fluctuations in relativistic nuclear collision
Gamma-widths, lifetimes and fluctuations in the nuclear quasi-continuum
Statistical -decay from highly excited states is determined by the
nuclear level density (NLD) and the -ray strength function
(SF). These average quantities have been measured for several nuclei
using the Oslo method. For the first time, we exploit the NLD and SF to
evaluate the -width in the energy region below the neutron binding
energy, often called the quasi-continuum region. The lifetimes of states in the
quasi-continuum are important benchmarks for a theoretical description of
nuclear structure and dynamics at high temperature. The lifetimes may also have
impact on reaction rates for the rapid neutron-capture process, now
demonstrated to take place in neutron star mergers.Comment: CGS16, Shanghai 2017, Proceedings, 5 pages, 3 figure
Physics Analysis Expert PAX: First Applications
PAX (Physics Analysis Expert) is a novel, C++ based toolkit designed to
assist teams in particle physics data analysis issues. The core of PAX are
event interpretation containers, holding relevant information about and
possible interpretations of a physics event. Providing this new level of
abstraction beyond the results of the detector reconstruction programs, PAX
facilitates the buildup and use of modern analysis factories. Class structure
and user command syntax of PAX are set up to support expert teams as well as
newcomers in preparing for the challenges expected to arise in the data
analysis at future hadron colliders.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics
(CHEP03), La Jolla, Ca, USA, March 2003, 7 pages, LaTeX, 10 eps figures. PSN
THLT00
Determining the shape of defects in non-absorbing inhomogeneous media from far-field measurements
International audienceWe consider non-absorbing inhomogeneous media represented by some refraction index. We have developed a method to reconstruct, from far-field measurements, the shape of the areas where the actual index differs from a reference index. Following the principle of the Factorization Method, we present a fast reconstruction algorithm relying on far field measurements and near field values, easily computed from the reference index. Our reconstruction result is illustrated by several numerical test cases
The weak localization for the alloy-type Anderson model on a cubic lattice
We consider alloy type random Schr\"odinger operators on a cubic lattice
whose randomness is generated by the sign-indefinite single-site potential. We
derive Anderson localization for this class of models in the Lifshitz tails
regime, i.e. when the coupling parameter is small, for the energies
.Comment: 45 pages, 2 figures. To appear in J. Stat. Phy
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